Skin Drug Delivery: Dermal, Transdermal & Microneedles65

Issue No #65 March 30th, 2016

Inside the magazine

VACCINE DELIVERY USING THE NEMAURA SOLID DOSE INJECTOR

VACCINE DELIVERY USING THE NEMAURA SOLID DOSE INJECTOR

Joanne Broadhead and Karmen Cheung report an investigation into the delivery of two vaccines using Nemaura Pharma’s solid-dose injection technology.

US FDA ISSUES GUIDANCE ON HUMAN FACTORS STUDIES FOR COMBINATION PRODUCTS

Dr Michael Gross

Chimera Consulting

US FDA ISSUES GUIDANCE ON HUMAN FACTORS STUDIES FOR COMBINATION PRODUCTS

Adam Shames and Michael Gross summarise the US FDA’s recently released draft Guidance: “Human Factors Studies and Related Clinical Study Considerations in Combination Product Design and Development”.

THE RAPID EVOLUTION OF THE TRANSDERMAL DRUG DELIVERY INDUSTRY SPAWNS INNOVATION

Trelleborg Sealing Solutions

THE RAPID EVOLUTION OF THE TRANSDERMAL DRUG DELIVERY INDUSTRY SPAWNS INNOVATION

Luis Tissone outlines technological developments behind microneedle design including the use of advanced liquid silicone rubber (LSR) and two-component injection technology, and explores the advantages this route offers over traditional intramuscular routes.

THE CRITICALITY OF ADHESIVE SELECTION FOR OPTIMAL TRANSDERMAL DRUG DELIVERY SYSTEMS

THE CRITICALITY OF ADHESIVE SELECTION FOR OPTIMAL TRANSDERMAL DRUG DELIVERY SYSTEMS

Megan Greth and Gozde Karabiyik discuss why selecting the right adhesive for body-worn drug delivery systems – be they transdermal patches or wearable injection devices or pumps – is critical for a successful outcome.

OPTIMISING <i>IN VITRO</i> TESTING FOR TRANSDERMAL AND TOPICAL DRUG PRODUCTS

Copley Scientific

OPTIMISING IN VITRO TESTING FOR TRANSDERMAL AND TOPICAL DRUG PRODUCTS

Tony Copley examines the regulatory framework for transdermal and topical products and popular, effective and cost-efficient in vitro testing techniques for quantifying their release characteristics.

NEW RESEARCH TOOLS FOR TOPICAL & TRANSDERMAL DEVELOPMENT

Prof Marc Brown

NEW RESEARCH TOOLS FOR TOPICAL & TRANSDERMAL DEVELOPMENT

Marc Brown, Rob Turner and James Gibbons provide a view on the current topical and transdermal market, elaborate on some of the common approaches to product development in this area, and reveal the company’s newest model, the MedFlux-HT™ system.

MICROBRISTLE APPLICATOR (MBA™) SYSTEMS FOR TOPICAL AND TRANSDERMAL DRUG APPLICATION

Pierre Michelet

GEKA Healthcare

MICROBRISTLE APPLICATOR (MBA™) SYSTEMS FOR TOPICAL AND TRANSDERMAL DRUG APPLICATION

Pierre Michelet, Karl Hartstock-Martin, and Moritz Beyhl present the innovative technology of microbristle applicators (MBA™) for a more precise and hygienic application within topical and transdermal treatment. MBA™ comprises a platform of moulded, pure plastic applicators with very fine bristles to apply liquid and semi-liquid formulations.