Novel Oral Drug Delivery Systems69

Issue No #69 July 25th, 2016

Inside the magazine

SELECTING OPTIMAL FORMULATION TECHNOLOGY FOR BETTER TREATMENT

SELECTING OPTIMAL FORMULATION TECHNOLOGY FOR BETTER TREATMENT

Stephen Tindal provides reviews strategies for oral formulation selection which can lower attrition rates, and therefore development costs and time to market.

ACCU-BREAK’S INNOVATIVE TABLET TECHNOLOGY – 2016 ADVANCEMENTS

Accu-Break Pharmaceuticals

ACCU-BREAK’S INNOVATIVE TABLET TECHNOLOGY – 2016 ADVANCEMENTS

David Beach provides a run-down of Accu-Break Pharmaceuticals’ tablet technologies which, among other benefits, allow patients to split tablets readily and reliably.

AN INNOVATIVE SMART ORAL DELIVERY TECHNOLOGY FOR PROTEINS AND PEPTIDES

AN INNOVATIVE SMART ORAL DELIVERY TECHNOLOGY FOR PROTEINS AND PEPTIDES

Andrea Engel, Anne Benedikt and Hans Baer explain how their recently introduced new modular platform technology for improving the oral bioavailability of peptides may offer a feasible solution to the problem of compliance with peptide drugs.

THE EMERGENCE OF CONTROLLED-RELEASE POWDERS FOR ORAL ADMINISTRATION

Dr Cory Berkland

THE EMERGENCE OF CONTROLLED-RELEASE POWDERS FOR ORAL ADMINISTRATION

Cory Berkland and Nathan Dormer look at what controlled-release powder delivery systems can offer, noting that a rising number of pharmaceutical companies and manufacturing organisations are incorporating controlled-release powder manufacturing to their portfolios.

THIN FILM EVOLVES TO LEVERAGE MUCOSAL DRUG DELIVERY BENEFITS

THIN FILM EVOLVES TO LEVERAGE MUCOSAL DRUG DELIVERY BENEFITS

Megan Greth and Scott Barnhart describe how thin film drug delivery systems are growing in importance as the benefits, such as improved drug bioavailability, reduced adverse events and avoidance of the first pass metabolism, are increasingly being recognised.

DIAL THE DOSE: A CLEVER DISPENSER FOR NON-STERILE LIQUIDS

DIAL THE DOSE: A CLEVER DISPENSER FOR NON-STERILE LIQUIDS

Paul Wismer explains how Balda's Dial-the-Dose product can help avoid the dangers of accidental overdose from using teaspoon- or tablespoon-based instructions for liquid medications, highlighted in several reports and studies, by improving the accuracy of liquid dosing.

NOVEL ORAL DRUG DELIVERY: INNOVATING TO SIMPLIFY

Dr Reddy's Laboratories

NOVEL ORAL DRUG DELIVERY: INNOVATING TO SIMPLIFY

Rashmi Nair and Praveen Raheja use case studies to illustrate their company’s approach to simplifying existing oral drug delivery systems, including osmotic and matrix tablet technologies.

A NOVEL APPROACH TO THE ORAL DELIVERY OF BIOLOGICS, PEPTIDES AND ANTIBODIES

A NOVEL APPROACH TO THE ORAL DELIVERY OF BIOLOGICS, PEPTIDES AND ANTIBODIES

Mir Imran provides an exclusive update on his company's groundbreaking robotic Auto-Pill™, which delivers a pain-free intestinal injection using a dissolvable needle made from materials that can be absorbed or easily passed out of the body.

ORAL THIN FILMS – REALMS OF POSSIBILITY?

LTS Lohmann Therapie-Systeme

ORAL THIN FILMS – REALMS OF POSSIBILITY?

Rick Chan, PhD, Executive Scientific Officer, LTS Lohmann Therapy Systems, discusses the fundamentals of transmucosal absorption and how formulation effort and the drug properties influence drug absorption in the buccal cavity.

WHY ORAL DISINTEGRATING TABLETS?

Dr Carmen Popescu

WHY ORAL DISINTEGRATING TABLETS?

Carmen Popescu provides an overview of the Orally Disintegrating Tablet (ODT) landscape, describing how these dosage forms can be used to improve and differentiate drug products, different manufacturing methods and how this class of oral delivery system might be applied in the future.

METHODOLOGIES FOR DEVELOPING s-SEDDS

Dr John Tillotson

ABITEC Corporation

METHODOLOGIES FOR DEVELOPING s-SEDDS

John Tillotson looks at the various methods available for manufacturing solid self-emulsifying drug delivery systems (s-SEDDS) and explores future possibilities of optimising these methods, which are growing in popularity as they offer advantages over liquids.