SUSTAINABILITY

REAL-TIME LCAs: CREATING “A SINGLE SOURCE OF TRUTH” FOR SUSTAINABILITY

Serena Grace and Marina Dumont offer insight into the development of a real-time operational model for lifecycle assessments, and detail how organisations can transform these analyses into robust decision-making tools.

RETHINKING DRUG DELIVERY: ENABLING RECYCLING AND MATERIAL EFFICIENCY IN HEALTHCARE

Dr Bernd Garska and Sven Schlecht highlight how single-use drug delivery devices can be re-thought to help solve the climate and environmental challenges in the healthcare sector.

MAINTAINING RELIABLE DRUG DELIVERY THROUGH SUSTAINABLE OPERATIONS

MAINTAINING RELIABLE DRUG DELIVERY THROUGH SUSTAINABLE OPERATIONS

Henryk Badack considers how a holistic approach to sustainability can enable CDMOs to implement efficient operations strategically – while introducing initiatives that address environmental, economic and social elements.

LATE-STAGE MATERIAL SUBSTITUTION: AMBITION FOR SUSTAINABILITY OR TRANSFER-TIME RISK?

LATE-STAGE MATERIAL SUBSTITUTION: AMBITION FOR SUSTAINABILITY OR TRANSFER-TIME RISK?

Kiara Taylor delves into the challenges of changing materials to enhance sustainability after a design has been transferred to manufacturing, considering the reasons that might drive such a change, the issues involved and the benefits that can be gained.

BIO-BASED PLASTICS IN DRUG DELIVERY: FROM MATERIAL EQUIVALENCE TO SYSTEMIC DECARBONISATION

Nadine Kaufmann

BIO-BASED PLASTICS IN DRUG DELIVERY: FROM MATERIAL EQUIVALENCE TO SYSTEMIC DECARBONISATION

Nadine Kaufmann and Michael Schori analyse the feasibility of introducing sustainable materials within current regulatory frameworks, demonstrating this with a range of Ypsomed products and illustrating ways to further integrate sustainable principles into the value chain.

SUSTAINABILITY IN DRUG DELIVERY

SUSTAINABILITY IN DRUG DELIVERY

Adam Tilley and David Cook explore how carbon footprint considerations can be integrated into the drug delivery device design lifecycle, highlighting key sustainability decisions faced by design engineers and emerging tools that support those evaluations.

Exclusive Interview: Taking Sustainability Beyond Compliance

Prof Hanns-Christian Mahler

Exclusive Interview: Taking Sustainability Beyond Compliance

Prof Hanns-Christian Mahler engages in a wide-ranging discussion about current challenges and trends in the drug delivery industry, particularly on the topic of sustainability – it’s advantages, difficulties and why companies should aim to do more than the bare minimum required by the regulation.

ECO-DESIGN DRIVING NEST AND READY-TO-USE PACKAGING INNOVATION

ECO-DESIGN DRIVING NEST AND READY-TO-USE PACKAGING INNOVATION

Lionel Maritan and François Ciavatti discuss RayDyLyo^®, an eco-designed nest developed to reduce the overall impact of ready-to-use components, reflecting on insights gained from lifecycle assessments, outlining the progress still to be made and illustrating how a pragmatic, inventive, eco-centric design approach can drive the development of packaging solutions with a measurably lower environmental footprint.

CHALLENGES & OPPORTUNITIES TO OPTIMISE SUSTAINABILITY IN PHARMACEUTICAL PACKAGING & COMBINATION DEVICES

CHALLENGES & OPPORTUNITIES TO OPTIMISE SUSTAINABILITY IN PHARMACEUTICAL PACKAGING & COMBINATION DEVICES

Greg Anderson discusses the need to improve the sustainability and circularity of pharmaceutical packaging and drug delivery devices, looking at the challenges and providing a clear outline of the potential opportunities for improvement.

REINVENTING THE pMDI: EVOLVING A PROVEN PLATFORM FOR A LOW-GWP FUTURE

REINVENTING THE pMDI: EVOLVING A PROVEN PLATFORM FOR A LOW-GWP FUTURE

Chris Baron discusses how lower-global warming potential pressurised metered dose inhalers are moving from development to commercialisation and explains why manufacturing readiness and supply resilience are critical, going on to introduce Aptar Pharma’s ZEN30 Futurity^®, designed to anticipate current and emerging regulatory expectations.

ENABLING A SUSTAINABLE FUTURE FOR pMDIs WITH LOW-GWP MEDICAL PROPELLANTS

Markus Laubscher

ENABLING A SUSTAINABLE FUTURE FOR pMDIs WITH LOW-GWP MEDICAL PROPELLANTS

Markus Laubscher discusses the role of pressurised metered dose inhalers in the context of healthcare’s drive towards sustainability, considering the need for lower-global-warming-potential propellants and why it is important to preserve these inhalers as a key aspect of respiratory care.

THE PHYSICS OF THE SWITCH: OPTIMISING pMDI DESIGN FOR LOW-CARBON LUNG DELIVERY

THE PHYSICS OF THE SWITCH: OPTIMISING pMDI DESIGN FOR LOW-CARBON LUNG DELIVERY

Thomas Daly and Tony Mallett discuss the transition to low-global warming potential propellants, examining the vital adjustments to the whole inhalation system necessary to support effective and safe dosing without hydrofluorocarbons.

Sustainable Packaging and Patient-Centric Design

Cambridge Design Partnership

Sustainable Packaging and Patient-Centric Design

Steve Augustyn and Jon Powell discuss a range of key topics in the drug delivery industry, including design complexity, sustainable materials and patient-centric design.

Sustainability, Balancing Priorities, and Bringing New Solutions to Market

Sustainability, Balancing Priorities, and Bringing New Solutions to Market

Steven Kaufman discusses the return of sustainability to the centre of drug delivery conversation and how Eco-Inject's novel autoinjector brings fresh thinking to the sector.

DESIGNING SUSTAINABLE DRUG DELIVERY DEVICE PACKAGING: TRENDS, CHALLENGES AND REGULATORY IMPLICATIONS

DESIGNING SUSTAINABLE DRUG DELIVERY DEVICE PACKAGING: TRENDS, CHALLENGES AND REGULATORY IMPLICATIONS

Angela Shotton and Nic Hunt, look at the evolving landscape of the pharmaceutical packaging landscape and consider how the industry is meeting sustainability and regulatory requirements.

CLOSING THE LOOP: DESIGNING THE FUTURE OF SUSTAINABLE DRUG DELIVERY DEVICES

CLOSING THE LOOP: DESIGNING THE FUTURE OF SUSTAINABLE DRUG DELIVERY DEVICES

Thuysi Dao outlines a two-pronged approach to improving the sustainability profile of drug delivery devices, combining sustainable device design with real-world take-back and recycling initiatives, and explores how Ypsomed’s new YpsoLoop autoinjector platform embodies this vision.

A BREATH OF FRESH AIR: PHARMA’S PUSH FOR SUSTAINABLE pMDIs

A BREATH OF FRESH AIR: PHARMA’S PUSH FOR SUSTAINABLE pMDIs

Andy Burns considers the driving factors for the transition to more sustainable propellants, as well as explaining the benefits and challenges of these next-generation propellants in terms of compatibility, performance, safety and global warming potential.

SCALING LOW-CARBON pMDI PRODUCTION WITHOUT DISRUPTING PATIENT ACCESS

SCALING LOW-CARBON pMDI PRODUCTION WITHOUT DISRUPTING PATIENT ACCESS

Simon Gardner looks at how the pharmaceutical industry is scaling up production of low-carbon pressurised metered dose inhalers to cut emissions without disrupting patient care. The article considers the challenges faced by the industry, as well as the role of CDMOs in creating sustainable, scalable solutions.

FROM PAPER TO PLANET: REVOLUTIONISING ENVIRONMENTAL RESPONSIBILITY IN PHARMA

PCI Pharma Services

FROM PAPER TO PLANET: REVOLUTIONISING ENVIRONMENTAL RESPONSIBILITY IN PHARMA

Lori Jackson and Tim Hansen look at the rise of electronic batch records and the role they play in environmental sustainability in the pharmaceutical landscape.

Interview: A Structured Approach to the Eco-Design Process

Fabien de Coninck

Interview: A Structured Approach to the Eco-Design Process

Fabien De Coninck and Bruno Morchain discuss Aptar Pharma’s eco-design philosophy with ONdrugDelivery’s Guy Furness. They cover how Aptar Pharma has implemented lifecycle assessments as a key tool to elucidate the environmental footprint of the company’s rubber components for primary packaging for injectable systems, including how they tackled the unique challenges presented by the complex, proprietary formulations involved in elastomer component design.

CIRCULAR DESIGN FOR SPRINGS AND PRESSINGS IN DRUG DELIVERY DEVICES

Bianca Plankenhorn

CIRCULAR DESIGN FOR SPRINGS AND PRESSINGS IN DRUG DELIVERY DEVICES

Bianca Plankenhorn discusses how sustainability is becoming an increasingly prominent and important part of the drug delivery industry, and how collaboration across the value chain – including steel spring and stampings manufacturers such as Lesjöfors – is critical for the industry to achieve its climate and emissions goals.

ADOPTION OF SUSTAINABILITY PRACTICES WITHIN SUBCUTANEOUS DRUG DELIVERY: INDUSTRY INSIGHTS

ADOPTION OF SUSTAINABILITY PRACTICES WITHIN SUBCUTANEOUS DRUG DELIVERY: INDUSTRY INSIGHTS

Conor O’Neill (GSK), Duncan Paterson (AstraZeneca) and Dr Monica Adams (GSK) come together to discuss a recent study conducted by the Subcutaneous Drug Development & Delivery Consortium among its member organisations, digging into the pharmaceutical industry’s progress and priorities when it comes to improving the environmental impact of subcutaneous medicines.

SUSTAINABLE DRUG DELIVERY SYSTEMS: COLLABORATIVE INNOVATION TO SHRINK PHARMA’S PACKAGING FOOTPRINT

SUSTAINABLE DRUG DELIVERY SYSTEMS: COLLABORATIVE INNOVATION TO SHRINK PHARMA’S PACKAGING FOOTPRINT

Maria Riccius and Dr Uwe Hanenberg explore how CDMOs are playing a pivotal role in driving drug delivery’s transformation towards sustainability, examining the most promising advances and highlighting why collaborative innovation is essential to achieving measurable environmental gains, both within organisations and across the pharmaceutical value chain.

SUSTAINABILITY AS STRATEGY: HOW PHARMA IS DRIVING CLIMATE INNOVATION

Dr Sofia Sotiropoulou

SUSTAINABILITY AS STRATEGY: HOW PHARMA IS DRIVING CLIMATE INNOVATION

Dr Sofia Sotiropoulou discusses the increasing emphasis that pharma companies are putting on sustainability metrics, and how they are extending this emphasis to their entire supply chains, placing expectations on design and manufacturing partners to participate in meeting sustainability targets.

Interview: Steven Kaufman. Delivering the Future – Inside the World of Autoinjector Innovation

Portal Instruments

Interview: Steven Kaufman. Delivering the Future – Inside the World of Autoinjector Innovation

Steven Kaufman talks with ONdrugDelivery’s Guy Furness about the world of autoinjectors, looking at the current status quo in the industry, using Portal’s PRIME Nexus™ smart reusable electromechanical autoinjector as a lens to bring into focus how things have changed and where they might be going.

SMARTER FOR BUDGETS & KINDER TO THE PLANET: ECOSAFE<sup>®</sup> SAFETY SYRINGE PLATFORM

SMARTER FOR BUDGETS & KINDER TO THE PLANET: ECOSAFE^® SAFETY SYRINGE PLATFORM

Tim Holden describes the key objectives behind Owen Mumford’s 1 mL safety syringe injection platform and how the company sought to provide a single platform for all patients (able, less dexterous and needle-phobic) while minimising cost, waste and carbon footprint impact.

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