EXPERT VIEW

EXPERT VIEW

EXTRACTABLES/LEACHABLES TESTING CONSIDERATIONS FOR SINGLE-USE SYSTEMS

Sandi Schaible discusses testing considerations for extractables and leachables along with the regulatory environment for single-use systems.

EXPERT VIEW

CONNECTED DRUG DELIVERY DEVICES: BENEFITS AND CYBERSECURITY

João Budzinski discusses the benefits of connected drug delivery devices and the importance of cybersecurity when developing them, including the threats, key considerations and potential solutions.

EXPERT VIEW

Dr Yannick Baschung

EXPANDING THE DESIGN OF CHARACTERISATION STUDIES FOR ACCURATE HANDLING-ERROR ASSESSMENT

Yannick Baschung discusses the importance of a comprehensive and accurate assessment of patient handling errors when it comes to inhaled product development.

EXPERT VIEW

James Silk

THE INFLUENCE OF UNCERTAINTY ON CHEMICAL CHARACTERISATION

James Silk discusses the importance of accounting for uncertainty when characterising the extractables profile of a medication, with particular reference to the ISO 10993 standard.

EXPERT VIEW

Marco Franza

THE INNOVATIONS TACKLING CHALLENGES & MAXIMISING OPPORTUNITIES IN INHALATION

Marco Franza and Nadine Khoury look at how the latest digital technologies, manufacturing techniques and packaging materials are combining to take the manufacture of inhalers to a new level.

EXPERT VIEW

Dr Heather Jameson

TAKING THE STING OUT OF VACCINES

Heather Jameson, Juliette Ngan and Omar Shah discuss the potential advantages and challenges of intranasal and inhaled vaccines in the context of global respiratory pandemics.

EXPERT VIEW

Dr Paul Kippax

SOLVING COMPLEX FORMULATION & DELIVERY CHALLENGES FOR INTRANASAL DRUGS

Paul Kippax discusses the analytical techniques used for in vitro characterisation of nasal sprays, and how their use can accelerate and de-risk both innovator and generic nasal drug development.

EXPERT VIEW

Mark Ignaczak

NASAL DELIVERY – A GALAXY NOT SO FAR AWAY… A BRIEF MARKET HISTORY OF THE NASAL DELIVERY LANDSCAPE

Mark Ignaczak provides an insight into the history of nasal drug delivery and looks at the advantages of the nasal delivery route.

EXPERT VIEW

Cormac O'Prey

SUSTAINABLE DESIGN & MANUFACTURE IN MEDICAL DEVICES: WHERE TO START

Cormac O’Prey discusses the challenges and advantages of implementing circular economy principles in the medical device sector, with a particular consideration of the difficulty of making remanufacturing work for high-volume, low-value devices.

EXPERT VIEW

Alastair Willoughby

THE ENVIRONMENTAL IMPACT OF GLOBAL SUPPLY CHAIN LOGISTICS & SUPPLIER SELECTION

Alastair Willoughby looks at the factors affecting sustainability when considering global supply chain logistics and supplier selection.

EXPERT VIEW

Catriona Eldridge

CLIMATE CHANGE AND THE PHARMACEUTICAL INDUSTRY: TOO LITTLE, TOO LATE?

Catriona Eldridge and Omar Shah discuss the findings of a recent investigative assessment into the environmental impact of healthcare products, and consider whether or not the pharmaceutical industry is doing enough to combat climate change.

EXPERT VIEW

Richard Whelton

AUTOINJECTORS: HISTORICAL ACHIEVEMENTS & COMPELLING NEEDS DRIVING NEXT-GENERATION DEVICES

Richard Whelton and Philip Green summarise the history of autoinjectors, highlight success stories to date, review the unmet needs that remain and consider emerging needs that could drive continued innovation in autoinjectors to ensure safety, patient satisfaction and pharma commercial success.

EXPERT VIEW

Tom Oakley

ON-BODY DELIVERY SYSTEMS – NEWS AND TRENDS

Tom Oakley discusses the current state of play in the on-body delivery system space, reviews recent milestones and proposes directions for the future.

EXPERT VIEW

Dave Beckstoffer

KEY CONSIDERATIONS WHEN SPECIFYING A MOTION SYSTEM FOR WEARABLE INJECTORS

The reliable performance of a wearable drug delivery device is understandably paramount, so optimising the motion solution that drives it is crucial. Dave Beckstoffer discusses how best to achieve this and ensure the best match between the motion solution and the characteristics of the specified drug or drug range.

EXPERT VIEW

Sara Dorman

IMPROVE YOUR BIOPHARMACEUTICAL WORKFLOW: 6 BENEFITS OF SINGLE-USE SYSTEM TECHNOLOGIES

Sara Dorman discusses the benefits of single-use systems, including how they help accelerate a drug product’s journey to market securely and more sustainably.

EXPERT VIEW

Jeff Lowe

SINGLE USE SYSTEMS – THE FUTURE OF BIOPHARMACEUTICAL PROCESSING

 Jeff Lowe considers single-use systems and looks at their role in the future of biopharmaceutical processing.

EXPERT VIEW

Dr Yongdong Zhou

DISSECTING THE DELICATE DELIVERY PROCESS FOR OCULAR GENE THERAPY

Yongdong Zhou considers the challenges of ocular gene therapy delivery approaches.

EXPERT VIEW

Rina Chokshi

FORMULATING SUPERIOR ORAL SUSPENSIONS FOR BETTER PATIENT COMPLIANCE

Rina Chokshi and Dago Caceres discuss how leveraging key ingredients in oral suspensions can enhance stability and sensory attributes, as well as encourage patient compliance.

EXPERT VIEW

Dr Bernard Vrijens

FOCUS ON ADHERENCE TO EMBRACE DCT BENEFITS

Bernard Vrijens looks at the effect of decentralised clinical trials on medication adherence in clinical studies.

EXPERT VIEW

Dr Ben Cox

HOW DIGITAL UX IN CLINICAL TRIALS CAN IMPROVE MEASURES

Ben Cox discusses the key challenges, principles and advantages of following a user-experience approach to digital health technologies in clinical trials.

EXPERT VIEW

Sylvia Kaiser

HOW RECENT NFC ADVANCES ENABLE ANTI-COUNTERFEIT DRUG CONTAINMENT & SUPPORT ADHERENCE

Sylvia Kaiser-Kershaw discusses how recent near-field communication tagging advancements can enable pharmaceutical companies to protect the authenticity and integrity of their products, while also making it easier for healthcare professionals and patients to use medications more effectively through intelligent drug delivery systems.

EXPERT VIEW

Gabrielle Whitworth-Smith

CYBERSECURITY AND THE CHALLENGES OF CLOUD CONNECTIVITY

Gabrielle Whitworth-Smith and Thomas Watts look at the benefits and risks associated with cloud connectivity and the accompanying cybersecurity challenges.

EXPERT VIEW

Napoleon Monroe

CONNECTIVITY IN HEALTHCARE – FROM THE MILLENNIUM TO THE PANDEMIC AND BEYOND

Napoleon Monroe looks back at the factors that influenced the underwhelming uptake of connectivity-enabling technologies in the healthcare sector over the first two decades of the 21st century, how the covid-19 pandemic changed everything and what current healthcare challenges connectivity might solve.

EXPERT VIEW

Paul Edalat

SMART DRUG DELIVERY DEVICES IMPROVE MEDICATION ADHERENCE: HERE’S HOW

Paul Edalat and Mehdi Hatamian take an in-depth look at medication non-adherence and how technology can be used to improve compliance rates and optimise patient outcomes.

EXPERT VIEW

Dr Anna Cifuentes-Rius

EXTRACELLULAR VESICLE ENGINEERING: OPTIMISING NATURE’S NON-IMMUNOGENIC, DRUG DELIVERY PLATFORM

Anna Cifuentes-Rius discusses the exciting potential of extracellular vesicles to advance drug delivery, in particular their natural ability to carry API payloads across difficult-to-traverse biological barriers.

EXPERT VIEW

Dr Martin Gonzalez

RECENT TRENDS & DEVELOPMENTS IN INJECTABLE FORMULATION & DELIVERY

Martin Gonzalez details current trends in sterile injectable formulations and their delivery devices, and the challenges pharma and its contract development and manufacturing company partners face in bringing emerging breakthroughs to market.

EXPERT VIEW

Rob Udale

ARE GOVERNMENTS BANNING THE MOST ENVIRONMENTALLY FRIENDLY INHALER?

Rob Udale, Catriona Eldridge and Omar Shah assess the assertion that pMDIs are the most environmentally damaging of the available pulmonary drug delivery device archetypes, and explore some of the intricacies not accounted for in the public discourse surrounding pMDIs.

EXPERT VIEW

Dr Jnanadeva Bhat

CAPSULES: CLASSIC DRUG DELIVERY FORM HOLDS POTENTIAL FOR SUSTAINABLE DELIVERY

Jnanadeva Bhat and Anita Solanki discuss the role that hard capsules are able to play in delivering a more sustainable pharmaceutical industry, both as an oral solid dosage form and in dry powder inhalers.

EXPERT VIEW

Frédérique Bordes-Picard

NANOTECHNOLOGY: A NEXT-GENERATION TOOL FOR PULMONARY & NASAL DELIVERY

Frédérique Bordes-Picard looks at the role of nanotechnology in the nasal and pulmonary routes of drug delivery and explains how nanoparticle explains how nanoparticle solutions could transform patient comfort and compliance.

EXPERT VIEW

Rob Udale

WAITING WITH BATED BREATH – WHAT’S IN STORE FOR 2022

Rob Udale and Heather Jameson discuss the exciting developments taking place in the design of inhalation devices and share their predictions for the top five inhalation trends to watch as 2022 unfolds, and beyond.

EXPERT VIEW

Wilbur de Kruijf

DO SOFT MIST INHALERS HOLD THE KEY TO FASTER INHALATION DRUG DEVELOPMENT?

Wilbur de Kruijf and Bernhard Müllinger discuss the the market requirements for new inhalation options and the benefits of soft mist inhalers.

EXPERT VIEW

Dr Justin Lacombe

USING QUALITY BY DESIGN TO OPTIMISE THE COMBINATION PRODUCT JOURNEY

Justin Lacombe and Julie D Suman explain how applying quality by design principles to combination products improves development efficiency, aligns with design controls, and maximises product safety and efficacy.

EXPERT VIEW

Dr Caterina Minelli

AN INVITATION TO PARTICIPATE IN STANDARDISATION OF PARTICLE MEASUREMENTS FOR PHARMACEUTICALS

Caterina Minelli discusses the importance of co-operation between metrology institutes and the pharmaceutical industry in the pursuit of improving analytical techniques and standards for the characterisation of particle attributes in drug development.

EXPERT VIEW

Daniel Lock

EVOLUTION OF NEBULISATION FOR DRUG DELIVERY TO THE LUNGS

Daniel Lock discusses the latest innovations in nebuliser technology for drug delivery to the lungs.

EXPERT VIEW

Anita Solanki

CAPSULES FOR DRY POWDER INHALATION – A COMPLETE PRODUCT

Anita Solanki, Jnanadeva Bhat and Justin Kalafat discuss capsules for dry powder formulation and consider their potential as a dosage form for patients with respiratory conditions and systemic illnesses.

EXPERT VIEW

Dr Yongdong Zhou

WHY GENE THERAPY IS PERFECT FOR TREATING OCULAR DISEASES

Yongdong Zhou discusses the applications, advantages and challenges of gene therapy in the ophthalmic sector.

EXPERT VIEW

Dr Jay S Duker

ENVISIONING NEW HORIZONS IN OCULAR DRUG DELIVERY

Jay S Duker discusses the history and future of ocular drug delivery, with a special focus on posterior segment diseases and the battle to overcome significant patient and caregiver burdens.

EXPERT VIEW

Robert Lee

KEEPING UP WITH THE DEMAND FOR EFFECTIVE OPHTHALMIC DRUGS

Robert Lee explores the growth of the ophthalmic drug market and discuss the challenges that pharma companies may face when creating drugs to treat some of the most common ocular indications.