EXPERT VIEW

EXPERT VIEW

“SOFTWARE AS A MEDICAL DEVICE” FROM A HUMAN FACTORS PERSPECTIVE

Natalie Shortt discusses the considerations and steps to take when planning usability engineering efforts for software as a medical device.

EXPERT VIEW

POWDER CHARACTERISATION: A CRITICAL TOOL FOR THE EVOLUTION OF INHALED DRUG DELIVERY

Jamie Clayton, Joana Pinto and Sarah Zellnitz discuss the benefits of multi-faceted powder characterisation in dry powder inhalation formulations and how it can support efforts to achieve net zero emissions.

EXPERT VIEW

Robert Lee

ADDRESSING THE CHALLENGES OF NASAL BIOTHERAPEUTIC DRUG DELIVERY

Robert Lee discusses the benefits of administering drugs to the nasal cavity, as well as the main challenges in formulation for this route and the strategies that can be applied to overcome them.

EXPERT VIEW

Cormac O'Prey

SUSTAINABILITY, WASTE & REMANUFACTURING IN THE MEDICAL SECTOR

Cormac O’Prey discusses some of the sustainability challenges facing the medical sector, such as how to make re-use and remanufacturing viable for high-volume, low-value products, and how answers can be found by looking to successful solutions deployed by other industries.

EXPERT VIEW

PHARMAPACK EUROPE DRUG DELIVERY AND PACKAGING ANNUAL SURVEY 2021

Pharmapack presents the results of its annual survey and market report, covering the latest Pharmapack Innovation Index and the inaugural Pharmapack Sustainability Index, and taking stock of where the survey results suggest the pharma industry currently is, and where it is heading, in terms of innovation and sustainability.

EXPERT VIEW

Charlie Dean

EIGHT ESSENTIAL SUSTAINABILITY TERMS FOR THE MEDICAL DEVICE INDUSTRY

Charlie Dean, Kay Sinclair and Brennan Miles provide an overview of eight terms key to a common understanding in the ongoing, and crucial, discussion surrounding sustainability.

INTERVIEW

Mathias Romacker

INTERVIEW WITH MATHIAS ROMACKER, EX-PFIZER, INJECTION DEVICES STRATEGY CONSULTANT

In this exclusive interview, Mathias Romacker discusses a broad range of topics, from his professional expertise and history seeing the parenteral sector evolve first-hand, to his personal experience as a Crohn’s disease patient making use of the very devices he’s seen grow and develop.

EXPERT VIEW

Enrico Denna

USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN

Enrico Denna looks at the advantages of a simulation and modelling approach over prototyping for the design of medical products.

EXPERT VIEW

Tim Resker

OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES

Tim Resker looks at new technologies for powering on battery-operated drug delivery devices while considering battery drain, ingress protection and user-friendliness.

EXPERT VIEW

Shaun Devitt

EXTENDING CONTAINER CLOSURE INTEGRITY TO WEARABLE INJECTORS

Shaun Devitt looks at how the principles and methods of container closure integrity might be adapted for wearable injectors.

EXPERT VIEW

Mr Denis Marteau

Owen Mumford

ARE VIRTUAL EVENTS A SUITABLE REPLACEMENT FOR FACE-TO-FACE EQUIVALENTS POST-PANDEMIC?

Denis Marteau looks at the future of virtual industry events and conferences in a post-pandemic future.

INDUSTRIALISATION

Napoleon Monroe

New Directions Technology Consulting

INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING

Napoleon Monroe considers the impact of the changing technological landscape on how industrialisation in the healthcare industry is evolving, with reference to the idea of “patients as consumers” and how the relationship between consumers, information and industry has evolved in other sectors, such as tech and retail – and how big players in those sectors are looking to move into and disrupt healthcare.

EXPERT VIEW

Richard Gray

AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE

Richard Gray and Julia Rashba-Step discuss the benefits of automated lipid nanoparticle production.

EXPERT VIEW

Robert Lee

OVERCOMING DEVELOPMENT OBSTACLES TO THE DELIVERY OF EFFECTIVE OCULAR THERAPY

Robert Lee discusses the growth of the ocular drug delivery market, the challenges formulators face in developing novel ocular technologies, and the role contract development and manufacturing organisations have to play in this growing market segment.

EXPERT VIEW

Dr Stephanie Emory

ADDRESSING ONGOING AND NEW BIOAVAILABILITY CHALLENGES

Stephanie Emory explores the pros and cons of various technologies for enhancing solubility and bioavailability for oral drug formulations. Further, Dr Emory draws on her experience as a reviewer at the US FDA to discuss how developers can view the FDA as a partner to aid success when leveraging innovative approaches.

EXPERT VIEW

Jamie Clayton

ANALYTICAL TECHNIQUES FOR THE FORMULATION OF GASTRORETENTIVE TABLETS

Jamie Clayton, Phil Bone and Kyu Mok Hwang discuss the value of analyses such as mercury porosimetry and powder rheology in characterising excipients for gastroretentive tablet formulation, and go on to detail a case study investigating polymer excipients for a novel bilayer floating tablet.

EXPERT VIEW

Dr Ben Cox

THE POWER OF ONBOARDING: BUILDING PERSUASIVE USER EXPERIENCES FOR COMPANION APPS

Ben Cox discusses the value of onboarding in drug delivery device companion apps, and how it is a key component of converting a one-time user to a repeat user, unlocking the true value of companion apps as a tool for combating poor adherence to medications and gathering high-quality data.

EXPERT VIEW

Dr Andrew Donnelly

ADDRESSING THE CHALLENGES OF VISCOUS INJECTABLE ADMINISTRATION

Andrew Donnelly and Shahid Uddin look at the challenges of self-administration of injectable viscous formulations and the technology that is helping to overcome these issues.

EXPERT VIEW

Mark Turner

BIOCOMPATIBILITY OF MEDICINAL PRODUCT MEDICAL DEVICE COMBINATIONS FOR AIRWAY DELIVERY

Mark Turner discusses biocompatibility testing for inhaled medical products, with particular reference to ISO 18562, and what Medical Engineering Technologies has learned from three years of breathing component biocompatibility testing.

EXPERT VIEW

Dr Stuart Madden

NASAL DELIVERY: AN OPPORTUNITY FOR SIGNIFICANT IMPROVEMENTS IN PATIENT CARE

Stuart Madden discusses the advantages of the nasal route of administration for the systemic delivery of therapeutics.

EXPERT VIEW

Dr Richard Johnson

FORMULATION OPTIONS IN NASAL DRUG DELIVERY

Richard Johnson discusses the advantages of nasal delivery and why there is growing interest in this route of administration, as well as considering some of the challenges that may arise during the development of nasal formulations for use in the clinic, and the regulatory and testing requirements associated with them.

EXPERT VIEW

Robert Lee

CONSIDERATIONS FOR OPHTHALMIC DRUG DELIVERY AND DEVELOPMENT

Robert Lee discusses recent advances in ophthalmic dosage forms and how companies are meeting these challenges to better serve their customers.

EXPERT VIEW

Dr Suresh Gupta

DRUG DELIVERY TO THE EYE: OVERCOMING THE CHALLENGES OF INTRAVITREAL PREFILLED SYRINGES

Suresh Gupta discusses the challenges of developing a PFS product for intravitreal injection, highlighting how designing for the intravitreal space, rather than the standard parenteral, imposes a number of additional requirements on the design.

EXPERT VIEW

Mr John Ross

LINKING THE “D” & “M” IN CDMO

John Ross looks at the role of CDMOs in product development through to commercialisation and considers the benefits of consolidated “DM” models.

EXPERT VIEW

Darren Mansell

ROOM FOR INNOVATION?

Darren Mansell examines US FDA guidance on biosimilar interchangeability and asks whether there is room for innovation.

EXPERT VIEW

Tom Oakley

TOP FIVE DRUG DELIVERY TRENDS FOR 2021

Tom Oakley provides an overview of the top five trends to expect in drug delivery in 2021.

EXPERT VIEW

Lars Skole

TACKLING PARENTERAL DRUG LABELLING’S SURGING COMPLEXITY

Lars Skole discusses emerging trends and challenges associated with growing parenteral packaging and labelling complexity – and how pharmaceutical developers and manufacturers can meet the challenges ahead.

EXPERT VIEW

George I’ons

CONNECTED DRUG DELIVERY: ACHIEVING OPTIMAL BENEFITS THROUGH SMART COLLABORATION

George I’ons discusses the challenges developing connected devices presents to key market stakeholders when it comes to successful rollout and implementation. Additionally, he considers the perspectives of these market players, as well as the patients themselves, with respect to how connected drug delivery devices can help them to better achieve their desired outcomes.

EXPERT VIEW

Beth Crandall

ECONOMIC OPERATORS UNDER THE EU MDR: THE NEW REQUIREMENTS

Beth Crandall spells out the new requirements for Economic Operators under the EU Medical Device Regulation.

EXPERT VIEW

Andy Fry

PREPARING FOR MASS VACCINATION

Andy Fry and Stephen Blatcher discuss the need for a mass vaccination device in response to the 2020 covid-19 pandemic. In particular, the authors discuss the benefits and challenges of turning to needle-free injection technology as a solution.

EXPERT VIEW

Allison Strochlic

CONDUCTING EFFECTIVE AND INFORMATIVE EVALUATIONS OF INJECTION DEVICE PACKAGING

Allison Strochlic and Andrea Dwyer discuss the often overlooked aspect of a combination product user interface: the packaging. With a specific look at injection devices, the authors cover how to perform proper human factors testing of a combination product’s packaging, and the advantages doing so can confer to a project.

EXPERT VIEW

Rina Chokshi

SUSTAINABLE PHARMACEUTICALS CAN OUTPERFORM THROUGH NATURALLY DERIVED INGREDIENTS & DEEP EXPERTISE

Rina Chokshi discusses the benefits of naturally derived, sustainable ingredients and their benefits to the environment and pharmaceutical industry.

EXPERT VIEW

Sergio Malorni

RETHINKING DRUG DELIVERY DEVICES FOR SUSTAINABILITY AND INNOVATION

Sergio Malorni and George Bostock discuss the issue of designing for sustainability, including going beyond “Reduce, Reuse, Recycle” to “Rethink” and looking to adjacent and consumer industries for inspiration on innovations the drug delivery industry can adopt with a view to reducing its environmental impact.

EXPERT VIEW

Rob Veasey

SUSTAINABILITY AND DRUG DELIVERY DEVICES

Rob Veasey explores the environmental challenges facing the drug delivery device industry – and the opportunities they bring.

EXPERT VIEW

Tom Oakley

WEARABLE INJECTORS: LATEST DEVICES & RECENT TRENDS

Wearable injection device expert Tom Oakley discusses recent trends in the space. He also takes a look at wearable injection devices currently on the market and considers the future of wearable injectors.

EXPERT VIEW

Frédérique Bordes-Picard

ADVANCED CAPSULE TECHNOLOGIES: DRY POWDER INHALERS TO TARGET DISEASE

Frédérique Bordes-Picard  and Julien Lamps discuss the value of capsule-based dry powder inhalers in the modern respiratory market, the factors driving development in this area and considerations for matching a capsule to a device and formulation.

EXPERT VIEW

María Fernández-Martos Balson

THE RISE OF COMPLEX ORAL DELIVERY SYSTEMS

María Fernández-Martos Balson and Bastiaan De Leeuw explore the oral delivery of biologics and the challenges that must be overcome in order to enhance bioavailability. The authors also take a look at some recently developed drug-device combinations.

EXPERT VIEW

Napoleon Monroe

COVID-19: A CATALYST FOR IMPLEMENTING CONNECTED HEALTHCARE PRODUCTS?

Napoleon Monroe analyses how covid-19 is catalysing a wide range of reactions in healthcare, explaining how drug and device connectivity are essential to improving patient access to treatment – and patient outcomes – as well as reducing overall cost.