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Pulmonary & Nasal Drug Delivery131

Issue No #131 April 2022  April 9th, 2022


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Issue 131 - Apr 2022

Inside the magazine

INVESTIGATING THE PROPELLANT PATHWAYS LEADING TO A SUSTAINABLE FUTURE FOR MDIS
SUSTAINABILITY
Chris Baron
Aptar Pharma
INVESTIGATING THE PROPELLANT PATHWAYS LEADING TO A SUSTAINABLE FUTURE FOR MDIS
Chris Baron and Jag Shur discuss the various dynamics involved in realising the full potential of MDIs to deliver both improved environmental performance and even better patient outcomes.
NANOTECHNOLOGY: A NEXT-GENERATION TOOL FOR PULMONARY & NASAL DELIVERY
EXPERT VIEW
Frédérique Bordes-Picard
NANOTECHNOLOGY: A NEXT-GENERATION TOOL FOR PULMONARY & NASAL DELIVERY
Frédérique Bordes-Picard looks at the role of nanotechnology in the nasal and pulmonary routes of drug delivery and explains how nanoparticle explains how nanoparticle solutions could transform patient comfort and compliance.
WAITING WITH BATED BREATH – WHAT’S IN STORE FOR 2022
EXPERT VIEW
Rob Udale
WAITING WITH BATED BREATH – WHAT’S IN STORE FOR 2022
Rob Udale and Heather Jameson discuss the exciting developments taking place in the design of inhalation devices and share their predictions for the top five inhalation trends to watch as 2022 unfolds, and beyond.
PERSONALISED AEROSOL LOADING AND MANAGEMENT (PALM): A HANDHELD DEVICE FOR AEROSOL DRUG DELIVERY
EARLY INSIGHT
Dr Jason Brenker
Monash University
PERSONALISED AEROSOL LOADING AND MANAGEMENT (PALM): A HANDHELD DEVICE FOR AEROSOL DRUG DELIVERY
Jason Brenker, Tuncay Alan and Daniela Traini introduce the PALM – Personalised Aerosol Loading and Management – device, a unique, advanced drug delivery device enabling personalised delivery of aerosols to improve the efficacy of inhaled medications and patient compliance.
DO SOFT MIST INHALERS HOLD THE KEY TO FASTER INHALATION DRUG DEVELOPMENT?
EXPERT VIEW
Wilbur de Kruijf
DO SOFT MIST INHALERS HOLD THE KEY TO FASTER INHALATION DRUG DEVELOPMENT?
Wilbur de Kruijf and Bernhard Müllinger discuss the the market requirements for new inhalation options and the benefits of soft mist inhalers.
NOSE-TO-BRAIN DRUG ADMINISTRATION AND A NOVEL APPROACH WITH AN OLD FAMILIAR
NASAL
Dr Marie-Christine Klein
Aero Pump
NOSE-TO-BRAIN DRUG ADMINISTRATION AND A NOVEL APPROACH WITH AN OLD FAMILIAR
Marie-Christine Klein, Andreas Bilstein and Rouven Kraus look at the advantages of the nose-to-brain route and soft mist nasal sprays for drug administration.
Technology Showcase: Testing Solutions for pMDI Drug Development
PULMONARY
Proveris Scientific
Technology Showcase: Testing Solutions for pMDI Drug Development
Proveris Scientific showcases its complete suite of testing solutions for pMDI drug development, which include Proveris by Design, Ergo Studies, Vereo SFMDx Actuators, and a new Kinaero Cx pMDI Collection System.
USING QUALITY BY DESIGN TO OPTIMISE THE COMBINATION PRODUCT JOURNEY
EXPERT VIEW
Dr Justin Lacombe
USING QUALITY BY DESIGN TO OPTIMISE THE COMBINATION PRODUCT JOURNEY
Justin Lacombe and Julie D Suman explain how applying quality by design principles to combination products improves development efficiency, aligns with design controls, and maximises product safety and efficacy.
INTERVIEW: JON LENN & JON VOLMER, MEDPHARM
INTERVIEW
Dr Jon Lenn
MedPharm
INTERVIEW: JON LENN & JON VOLMER, MEDPHARM
Jon Lenn and Jon Volmer talked with Guy Furness about the importance of nasal modelling, focusing on MedPharm’s own nasal cavity modelling technology, MedCast, its unique characteristics and benefits and the value it brings to the company’s offering for nasally delivered products.
AN INVITATION TO PARTICIPATE IN STANDARDISATION OF PARTICLE MEASUREMENTS FOR PHARMACEUTICALS
EXPERT VIEW
Dr Caterina Minelli
AN INVITATION TO PARTICIPATE IN STANDARDISATION OF PARTICLE MEASUREMENTS FOR PHARMACEUTICALS
Caterina Minelli discusses the importance of co-operation between metrology institutes and the pharmaceutical industry in the pursuit of improving analytical techniques and standards for the characterisation of particle attributes in drug development.
NASAL DELIVERY SYSTEM EXPANDS PUBLIC AND PATIENT ACCESS TO NALOXONE TO MITIGATE THE OPIOID OVERDOSE EPIDEMIC
NASAL
Dr Todd Pizitz
NASAL DELIVERY SYSTEM EXPANDS PUBLIC AND PATIENT ACCESS TO NALOXONE TO MITIGATE THE OPIOID OVERDOSE EPIDEMIC
Todd D Pizitz and Donald R Mealing discuss the ongoing US opioid epidemic, the CounterAct cap containing a single dose of naloxone to be attached to prescribed opioids, and a recent pilot market study done to gauge public enthusiasm for this life-saving technology.
EVOLUTION OF NEBULISATION FOR DRUG DELIVERY TO THE LUNGS
EXPERT VIEW
Daniel Lock
EVOLUTION OF NEBULISATION FOR DRUG DELIVERY TO THE LUNGS
Daniel Lock discusses the latest innovations in nebuliser technology for drug delivery to the lungs.
MANUFACTURING DPIs: AN ENGINEERING PERSPECTIVE
PULMONARY
Pietro Pirera
IMA Group
MANUFACTURING DPIs: AN ENGINEERING PERSPECTIVE
Pietro Pirera discusses the optimal process parameters for microdose dry power inhalers achieved by dosator technology.
ADDRESSING SYSTEMIC DELIVERY WITH A UNIT-DOSE NASAL SPRAY
NASAL
Audrey Chandra
Nemera
ADDRESSING SYSTEMIC DELIVERY WITH A UNIT-DOSE NASAL SPRAY
Audrey Chandra and Raphaële Audibert discuss the benefits of a unit-dose nasal spray for rapid treatment in an emergency.
BREACHING THE BLOOD-BRAIN-BARRIER WITH PARTICLE-BASED NASAL DELIVERY SYSTEMS
NASAL
Tom French
3P Innovation
BREACHING THE BLOOD-BRAIN-BARRIER WITH PARTICLE-BASED NASAL DELIVERY SYSTEMS
Tom French talks about the advantages of the nasal drug delivery route and crossing the blood-brain-barrier to treat central nervous system diseases.
CAPSULES FOR DRY POWDER INHALATION – A COMPLETE PRODUCT
EXPERT VIEW
Anita Solanki
CAPSULES FOR DRY POWDER INHALATION – A COMPLETE PRODUCT
Anita Solanki, Jnanadeva Bhat and Justin Kalafat discuss capsules for dry powder formulation and consider their potential as a dosage form for patients with respiratory conditions and systemic illnesses.
COLLABORATION AIMS TO ACCELERATE DEVELOPMENT PROCESS IN DPI FORMULATION
PULMONARY
Harry Peters
DFE Pharma
COLLABORATION AIMS TO ACCELERATE DEVELOPMENT PROCESS IN DPI FORMULATION
Harry Peters explains how the collaboration between DFE Pharma, Hosokawa Micron and Harro Höfliger can help manufacturers save time and money in the development process for dry powder inhalers, enabling them to tackle unmet needs and unleash the potential of the significant market opportunity presented by dry powder inhalers.
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