Prefilled Syringes & Injection Devices83

Issue No #83 February 5th, 2018

Inside the magazine

INJECTING HIGH VOLUME, HIGH VISCOSITY DRUGS

PREFILLED SYRINGES

INJECTING HIGH VOLUME, HIGH VISCOSITY DRUGS

SHL details its latest offerings in the world of biologics, as well as its partnership with QuiO, a speciality digital healthcare start-up, to develop injectables in the connected healthcare space.

SUPERCAPSYRINGE<sup>®</sup> PASSES THE TEST

Hans Peter Manser

SUPERCAPSYRINGE^® PASSES THE TEST

Hans Peter Manser, Lisa Lippuner and Sarah Raible discuss the findings of a study conducted to test the qualities of Weibel’s SuperCapSyringe^®.

FROM PREFILLED SYRINGES TO COMBI-FILLING

FROM PREFILLED SYRINGES TO COMBI-FILLING

Klaus Ullherr summarises the state of modern packaging technology in the pharmaceutical industry in the light of the biotech boom, ready-to-fill and pre-sterilised containers and the trend towards individualised healthcare.

CONTROLLING AUTOINJECTOR NEEDLE INSERTION AND INJECTION SPEED

PREFILLED SYRINGES

CONTROLLING AUTOINJECTOR NEEDLE INSERTION AND INJECTION SPEED

Pascal Dugand relates a study conducted by Nemera to determine a way to optimise the transition from needle insertion to syringe emptying for parenteral devices. This piece was originally presented as a poster at PDA Vienna 2017.

AN OPTIMISED PLATFORM FOR HIGHLY SENSITIVE BIOLOGICS

PREFILLED SYRINGES

AN OPTIMISED PLATFORM FOR HIGHLY SENSITIVE BIOLOGICS

Alessio Bonati discusses the problematic interactions between drugs and their primary containers and goes on to introduce the Alba platform, Ompi’s range of primary glass containers designed to unify drug-container interactions over a product’s lifecycle.

PREFILLABLE SYRINGE DEVELOPMENTS TO MEET BIOTECH DRUG NEEDS

PREFILLED SYRINGES

Claudia Petersen

PREFILLABLE SYRINGE DEVELOPMENTS TO MEET BIOTECH DRUG NEEDS

Claudia Petersen looks at the technological advances being made to ensure prefillable syringes are compatible with protein-based, biotech-derived drugs.

DIGITISATION & INDUSTRY 4.0 IN PHARMA PRODUCTION

Christoph Hammer

DIGITISATION & INDUSTRY 4.0 IN PHARMA PRODUCTION

Christoph Hammer gives an overview of the Industry 4.0 concept, and its pharmaceutical application Pharma 4.0. Furthermore, Mr Hammer provides examples of what Pharma 4.0 can offer, discussing solutions shown at Interpak 2017, Düsseldorf.

SUNDEEP KANKANALA, BD

Dr Sundeep Kankanala

BD (Becton Dickinson & Company)

SUNDEEP KANKANALA, BD

Sundeep Kankanala discusses the challenges faced by today’s biopharmaceutical industry, in particular those posed by the need for large volumes and the issues caused by the use of silicone in prefilled syringes.

A NOVEL PRECISION-TARGETED ENDOVASCULAR DELIVERY SYSTEM

Paul J Fitzpatrick

Advanced Catheter Therapies

A NOVEL PRECISION-TARGETED ENDOVASCULAR DELIVERY SYSTEM

Paul J Fitzpatrick introduces the Occlusion Perfusion Catheter™, an innovative device that can target high concentrations of drug to precisely defined locations.

CRITICAL CONSIDERATIONS FOR HIGH VISCOSITY/HIGH VOLUME DEVICES

PREFILLED SYRINGES

Phillips-Medisize

CRITICAL CONSIDERATIONS FOR HIGH VISCOSITY/HIGH VOLUME DEVICES

There are some device design considerations that are common across the spectrum of biologics development. Bill Welch discusses these considerations, highlighting the advantage conferred by accounting for them early in the product lifecycle.

JOHN A MERHIGE, CREDENCE MEDSYSTEMS

Credence MedSystems

JOHN A MERHIGE, CREDENCE MEDSYSTEMS

John Merhige discusses Credence’s Companion Safety Syringe System, new advances in the product development pipeline, customer/market driven feedback from user studies and exciting developments planned for 2018 that will take the company on to the next major phase in its growth.

RECONSTITUTION DEVICES: MIXING, POWER, PACKAGING & REGULATION

Charlotte Harvey

RECONSTITUTION DEVICES: MIXING, POWER, PACKAGING & REGULATION

Charlotte Harvey discusses the challenge of reconstituting lyophilised drugs, both from the perspective of the drug itself and the delivery device associated with it.

THE INCREASING REQUIREMENTS FOR HUMAN FACTORS CONSIDERATIONS

PREFILLED SYRINGES

Dr Karen Guerrero

BD (Becton Dickinson & Company)

THE INCREASING REQUIREMENTS FOR HUMAN FACTORS CONSIDERATIONS

Karen Guerrero outlines how human factors engineering, now an essential requirement for all new drug delivery combination product approvals, can represent a significant challenge and how BD can help streamline this aspect of the development process.

ADDRESSING HUMAN FACTORS STUDIES AT AN EARLY STAGE

PREFILLED SYRINGES

ADDRESSING HUMAN FACTORS STUDIES AT AN EARLY STAGE

Orfeo Niedermann and Jakob Lange provide insights into the development of platform products that offer pharma companies low risks and shorter timelines at an attractive cost, using the examples of the YpsoMate autoinjector and UnoPen pen injector platform products.

A PATIENT-CENTRIC APPROACH TO THERAPY MANAGEMENT

A PATIENT-CENTRIC APPROACH TO THERAPY MANAGEMENT

Karl Hewson and Uri Baruch discuss the challenges presented by chronic illness, and look ahead to a better future of patient-centric treatment, personalised to each individual’s needs.

IMPROVING PATIENT EXPERIENCE WITH NEW ONBOARDING TECHNIQUES

PREFILLED SYRINGES

IMPROVING PATIENT EXPERIENCE WITH NEW ONBOARDING TECHNIQUES

Paul Sullivan outlines how the growing trend towards patient self-injection, outside of the clinical setting, places an ever greater emphasis on quality training and onboarding. Mr Sullivan specifically explains how such training can help overcome the issue of patient needle fear or anxiety.