ONdrugDelivery | Global Drug Delivery Industry Information & Intelligence

SUSTAINABILITY

CLOSING THE LOOP: DESIGNING THE FUTURE OF SUSTAINABLE DRUG DELIVERY DEVICES

Thuysi Dao outlines a two-pronged approach to improving the sustainability profile of drug delivery devices, combining sustainable device design with real-world take-back and recycling initiatives, and explores how Ypsomed’s new YpsoLoop autoinjector platform embodies this vision.

A BREATH OF FRESH AIR: PHARMA’S PUSH FOR SUSTAINABLE pMDIs

Andy Burns considers the driving factors for the transition to more sustainable propellants, as well as explaining the benefits and challenges of these next-generation propellants in terms of compatibility, performance, safety and global warming potential.

ADOPTION OF SUSTAINABILITY PRACTICES WITHIN SUBCUTANEOUS DRUG DELIVERY: INDUSTRY INSIGHTS

Conor O’Neill (GSK), Duncan Paterson (AstraZeneca) and Dr Monica Adams (GSK) come together to discuss a recent study conducted by the Subcutaneous Drug Development & Delivery Consortium among its member organisations, digging into the pharmaceutical industry’s progress and priorities when it comes to improving the environmental impact of subcutaneous medicines.

SCALING LOW-CARBON pMDI PRODUCTION WITHOUT DISRUPTING PATIENT ACCESS

SCALING LOW-CARBON pMDI PRODUCTION WITHOUT DISRUPTING PATIENT ACCESS

Simon Gardner looks at how the pharmaceutical industry is scaling up production of low-carbon pressurised metered dose inhalers to cut emissions without disrupting patient care. The article considers the challenges faced by the industry, as well as the role of CDMOs in creating sustainable, scalable solutions.

FROM PAPER TO PLANET: REVOLUTIONISING ENVIRONMENTAL RESPONSIBILITY IN PHARMA

PCI Pharma Services

FROM PAPER TO PLANET: REVOLUTIONISING ENVIRONMENTAL RESPONSIBILITY IN PHARMA

Lori Jackson and Tim Hansen look at the rise of electronic batch records and the role they play in environmental sustainability in the pharmaceutical landscape.

Interview: A Structured Approach to the Eco-Design Process

Fabien de Coninck

Interview: A Structured Approach to the Eco-Design Process

Fabien De Coninck and Bruno Morchain discuss Aptar Pharma’s eco-design philosophy with ONdrugDelivery’s Guy Furness. They cover how Aptar Pharma has implemented lifecycle assessments as a key tool to elucidate the environmental footprint of the company’s rubber components for primary packaging for injectable systems, including how they tackled the unique challenges presented by the complex, proprietary formulations involved in elastomer component design.

CIRCULAR DESIGN FOR SPRINGS AND PRESSINGS IN DRUG DELIVERY DEVICES

Bianca Plankenhorn

CIRCULAR DESIGN FOR SPRINGS AND PRESSINGS IN DRUG DELIVERY DEVICES

Bianca Plankenhorn discusses how sustainability is becoming an increasingly prominent and important part of the drug delivery industry, and how collaboration across the value chain – including steel spring and stampings manufacturers such as Lesjöfors – is critical for the industry to achieve its climate and emissions goals.

SUSTAINABLE DRUG DELIVERY SYSTEMS: COLLABORATIVE INNOVATION TO SHRINK PHARMA’S PACKAGING FOOTPRINT

SUSTAINABLE DRUG DELIVERY SYSTEMS: COLLABORATIVE INNOVATION TO SHRINK PHARMA’S PACKAGING FOOTPRINT

Maria Riccius and Dr Uwe Hanenberg explore how CDMOs are playing a pivotal role in driving drug delivery’s transformation towards sustainability, examining the most promising advances and highlighting why collaborative innovation is essential to achieving measurable environmental gains, both within organisations and across the pharmaceutical value chain.

SUSTAINABILITY AS STRATEGY: HOW PHARMA IS DRIVING CLIMATE INNOVATION

Dr Sofia Sotiropoulou

SUSTAINABILITY AS STRATEGY: HOW PHARMA IS DRIVING CLIMATE INNOVATION

Dr Sofia Sotiropoulou discusses the increasing emphasis that pharma companies are putting on sustainability metrics, and how they are extending this emphasis to their entire supply chains, placing expectations on design and manufacturing partners to participate in meeting sustainability targets.

Drug Delivery to the Lungs (DDL 2025)

10th Dec 2025 - 12th Dec 2025

Edinburgh, UK

Drug Delivery to the Lungs (DDL 2025)

DDL, in its 36th year, attracts >1100 attendees including scientists, academics, clinicians, regulators and industry experts. The conference includes a large industry exhibition supported by 117 international companies, a scientific poster hall, expert lectures and excellent networking opportunities. DDL supports young scientists by offering free registration for students, career development grants and a variety of awards.

USING OXYCAPT™ MULTILAYER PLASTIC VIAL FOR GENE AND CELL THERAPIES STORED IN DRY ICE AND LIQUID NITROGEN

PREFILLED SYRINGES

Hiroki Hasegawa

Mitsubishi Gas Chemical

USING OXYCAPT™ MULTILAYER PLASTIC VIAL FOR GENE AND CELL THERAPIES STORED IN DRY ICE AND LIQUID NITROGEN

Hiroki Hasegawa and Tomohiro Suzuki consider the various challenges presented by cold-chain logistics to both traditional glass vials and many cyclo-olefin polymer alternatives, and how Mitsubishi Gas Chemical's OXYCAPT™ vials offer significant advantages for maintaining container closure integrity compared with other materials on the market.

PROVING THE DESIGN SPACE: ADVANCING THE DEVELOPMENT OF SYRINGE-DEVICE COMBINATIONS

PREFILLED SYRINGES

Enrico Barichello

Stevanato Group

PROVING THE DESIGN SPACE: ADVANCING THE DEVELOPMENT OF SYRINGE-DEVICE COMBINATIONS

Enrico Barichello and Courtney Nicholas Sutton the innovative combination of the Molly^® autoinjector with Alba^® and Nexa^® prefilled syringes, which addresses the need to streamline device approval by establishing comprehensive compatibility testing, collaboration between suppliers and validated solutions for drug delivery.

AUTOINJECTORS VERSUS ON-BODY SYSTEMS: THE FUTURE OF LARGE-VOLUME DELIVERY

AUTOINJECTORS VERSUS ON-BODY SYSTEMS: THE FUTURE OF LARGE-VOLUME DELIVERY

Dr Alex Vasiev and Dr Ethan Miller weigh up the benefits and costs of using on-body injectors versus autoinjectors, discussing delivery, design and patient population variability alongside recent advances in on-body injector development.

Interview: Steven Kaufman. Delivering the Future – Inside the World of Autoinjector Innovation

Portal Instruments

Interview: Steven Kaufman. Delivering the Future – Inside the World of Autoinjector Innovation

Steven Kaufman talks with ONdrugDelivery’s Guy Furness about the world of autoinjectors, looking at the current status quo in the industry, using Portal’s PRIME Nexus™ smart reusable electromechanical autoinjector as a lens to bring into focus how things have changed and where they might be going.

ALTERNATIVE APPROACH FOR DEVICE SUBSTITUTABILITY: HUMAN FACTORS STUDIES FOR GENERICS & BIOSIMILARS

Carrie O’Donel

Teva Pharmaceuticals

ALTERNATIVE APPROACH FOR DEVICE SUBSTITUTABILITY: HUMAN FACTORS STUDIES FOR GENERICS & BIOSIMILARS

Carrie O’Donel, Henri Akouka, Mark DeStefano along with Leslie Sanchez-Torres, discuss the shortcomings of current comparative use approaches to determining substitutability of devices for generics and biosimilars and propose an alternative approach to human factors studies based on long-standing methodologies that has the potential to unlock innovation and improve the user experience for patients.

INFLUENCE OF MACHINE CONCEPTS ON OVERALL EQUIPMENT EFFECTIVENESS

INDUSTRIALISATION

Dr Carsten Köhler

INFLUENCE OF MACHINE CONCEPTS ON OVERALL EQUIPMENT EFFECTIVENESS

Carsten Köhler provides an overview of the key metrics that contribute to overall equipment effectiveness for manufacturing drug delivery devices, detailing some of the options available when considering large-scale, high-volume manufacture.

NOLATO’S VIRTUAL FACTORY IN ACTION: ACCELERATING DRUG DELIVERY INNOVATION

INDUSTRIALISATION

Patrik Ingvarsson

NOLATO’S VIRTUAL FACTORY IN ACTION: ACCELERATING DRUG DELIVERY INNOVATION

Patrik Ingvarsson discusses Nolato’s virtual factory methodology, wherein embedded technical experts help drug delivery device developers reduce risk, costs and time to market through intelligent application of simulations to facilitate smoother and more robust development cycles with fewer iterations required.

FROM CARTRIDGE TO COMMERCIALISATION – UNDERSTANDING THE FILL-FINISH PROCESS

PREFILLED SYRINGES

Grand River Aseptic Manufacturing

FROM CARTRIDGE TO COMMERCIALISATION – UNDERSTANDING THE FILL-FINISH PROCESS

Chelsea Keeton digs into the challenging yet often overlooked process of fill-finish, discussing the particular hurdles and considerations that come with filling drug products into primary containers, with an emphasis on cartridges and their role in an injectables landscape increasingly influenced by the needs of biologics.

HIGH-SPEED ASSEMBLY OF NEEDLE SHIELDS FOR PREFILLED SYRINGES

INDUSTRIALISATION

Matthias Müller

HIGH-SPEED ASSEMBLY OF NEEDLE SHIELDS FOR PREFILLED SYRINGES

Matthias Müller discusses the factors that set exceptional manufacturing equipment apart from the rest and how Contexo's new machine for assembling needle shields with prefilled syringes meets all these expectations.

INSIDE A TRACK-AND-TRACE SYSTEM FOR MEDICAL MOULDS: A MODEL FOR HEALTHCARE MANUFACTURING

INDUSTRIALISATION

INSIDE A TRACK-AND-TRACE SYSTEM FOR MEDICAL MOULDS: A MODEL FOR HEALTHCARE MANUFACTURING

Twan Mertens and Floor Verhorst-Willems explore how IGS GeboJagema provides comprehensive visibility into every aspect of its operations with a 100% control track-and-trace process, spanning from initial sales discussions through to final validation and beyond.

LAUNCHING A LARGE-VOLUME PREFILLABLE GLASS SYRINGE SYSTEM: RELIABLE SUBCUTANEOUS DRUG DELIVERY

PREFILLED SYRINGES

Isabelle Jeangoudoux

LAUNCHING A LARGE-VOLUME PREFILLABLE GLASS SYRINGE SYSTEM: RELIABLE SUBCUTANEOUS DRUG DELIVERY

Isabelle Jeangoudoux and Sven Pohle introduce SCHOTT Pharma’s new syriQ BioPure 5.5 mL staked-needle prefillable glass syringe and explain how this solution meets the growing need for large-volume subcutaneous drug delivery.

ENSURING EXCELLENCE IN MANUFACTURING

PREFILLED SYRINGES

Baumann Medical

ENSURING EXCELLENCE IN MANUFACTURING

David Pircher, Pavel Zahradník and Maxime Ludwig discuss the medical mindset in the context of quality and present examples and tools that are used in practice.

HOW COC SYRINGES ARE SHAPING THE FUTURE OF INJECTABLE DRUG DELIVERY

PREFILLED SYRINGES

Tom Van Ginneken

Wirthwein Medical

HOW COC SYRINGES ARE SHAPING THE FUTURE OF INJECTABLE DRUG DELIVERY

Tom Van Ginneken explores the advantages of cyclo-olefin copolymer syringes, including where they outperform glass, which applications benefit most and why many common objections are outdated or debunked by current data, market adoption and technological advances.

CUSTOM METAL SOLUTIONS FOR EMERGING CHALLENGES IN AUTOINJECTOR SYSTEMS

PREFILLED SYRINGES

CUSTOM METAL SOLUTIONS FOR EMERGING CHALLENGES IN AUTOINJECTOR SYSTEMS

Iker Ibisate, Álvaro García Nograro and Irakusne Incierte, address the complex manufacturing challenges posed by increasingly sophisticated autoinjector devices and introduce RPK Medical’s approach as a technical partner in overcoming these challenges through the tailored design and manufacture of functional metal components, such as precision springs and stamped parts.

MORE THAN THE SUM OF ITS PARTS: HOW SUPPLIER COLLABORATION DRIVES SUCCESSFUL COMBINATION PRODUCTS

MORE THAN THE SUM OF ITS PARTS: HOW SUPPLIER COLLABORATION DRIVES SUCCESSFUL COMBINATION PRODUCTS

Bernd Zeiss, Lucy Lee and Sébastien Cordier discuss the multitudinous advantages of collaboration between suppliers and pharma partners, from boosting innovation to optimising component choices for device development early on, all while ensuring compliance with global regulatory standards.

SMARTER FOR BUDGETS & KINDER TO THE PLANET: ECOSAFE<sup>®</sup> SAFETY SYRINGE PLATFORM

SMARTER FOR BUDGETS & KINDER TO THE PLANET: ECOSAFE^® SAFETY SYRINGE PLATFORM

Tim Holden describes the key objectives behind Owen Mumford’s 1 mL safety syringe injection platform and how the company sought to provide a single platform for all patients (able, less dexterous and needle-phobic) while minimising cost, waste and carbon footprint impact.

ADVANCEMENTS IN INTRADERMAL DELIVERY: FROM HISTORIC TECHNIQUES TO MODERN INNOVATIONS

Terumo Medical Care Solutions

ADVANCEMENTS IN INTRADERMAL DELIVERY: FROM HISTORIC TECHNIQUES TO MODERN INNOVATIONS

Michele Guasti explores the evolution of intradermal delivery methods, comparing historic methods of delivery, such as the Mantoux technique, with modern innovations, such as the Terumo Immucise™ intradermal injection system. The article goes on to discuss the expanding applications of intradermal delivery, including its potential for targeted lymph node delivery.

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