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GLAUCOMA IN VIEW: IMPROVING PATIENT ADHERENCE WITH PRESERVATIVE-FREE, MULTIDOSE EYEDROPPERS

Nemera's Zoë Davidson considers the impact of glaucoma on global health and the challenges presented by its increasing prevalence in the ageing global population, discussing how the Novelia^® multidose eyedropper for preservative-free formulations is well-positioned to address challenges in glaucoma treatment, from ease of use to sustainability.

A NEW DELIVERY PLATFORM FOR SUPRACHOROIDAL ADMINISTRATION USING WEST’S ADVANCEABLE MICRONEEDLE DEVICE

Anu Prabhathachandran, Menachem Peretz and Manali Potnis discuss the growing need for more effective delivery of ophthalmic therapeutics to meet the needs of the ageing population, including how delivery into the suprachoroidal space may present an appealing alternative to intravitreal injection. They introduce West Pharmaceutical Service’ Suprachoroidal Advanceable Microneedle Device, which offers several advantages for overcoming the challenges with suprachoroidal space.

REVOLUTIONISING EYE CARE: THE POTENTIAL OF ANTISENSE OLIGONUCLEOTIDES

Binbin Tian discusses antisense oligonucleotides and considers their potential as treatments for genetic and multifactorial ophthalmic diseases previously considered untreatable. The article considers how these therapies function as treatments, their current state of development, challenges in their delivery and the evolving regulatory landscape

A COMPREHENSIVE APPROACH TO ADDRESSING UNMET NEEDS IN INTRAVITREAL INJECTIONS

Dr Reza Abedian

A COMPREHENSIVE APPROACH TO ADDRESSING UNMET NEEDS IN INTRAVITREAL INJECTIONS

Dr Reza Abedian, Marie Stockton and Bernd Zeiss consider the complexities and clinical unmet needs of intravitreal injections and discuss how Gerresheimer’s syringe technology can help overcome these challenges.

GENE THERAPY IN OPHTHALMOLOGY: ADVANCES AND CHALLENGES

GENE THERAPY IN OPHTHALMOLOGY: ADVANCES AND CHALLENGES

Joe Batley and Lorna Barron provide an overview of the latest cutting-edge ophthalmic delivery methods and discuss possible future developments.

INTRODUCING THE TERUMO INJECTION FILTER NEEDLE – A FIRST STEP OF THE INFINO™ DEVELOPMENT PROGRAMME

Terumo Medical Care Solutions

INTRODUCING THE TERUMO INJECTION FILTER NEEDLE – A FIRST STEP OF THE INFINO™ DEVELOPMENT PROGRAMME

Thomas Isaac considers the issues associated with injection to highly sensitive areas, such as the vitreous body, and the potential to optimise needle design and features to address these issues, discussing the key features of Terumo’s Injection Filter Needle, indicated for hypodermic and intravitreal injections within this context.

THE RISE OF LARGE-VOLUME SUBCUTANEOUS ADMINISTRATION OF BIOPHARMACEUTICALS, AND DELIVERY IMPLICATIONS

Dr Andreas Schneider

THE RISE OF LARGE-VOLUME SUBCUTANEOUS ADMINISTRATION OF BIOPHARMACEUTICALS, AND DELIVERY IMPLICATIONS

Andreas Schneider and Jakob Lange consider the SC administration of larger volumes of biopharmaceuticals in the pharma industry and summarise a recent study that reviews clinical-stage and approved IV and SC biopharmaceuticals to provide valuable guidance for new product development, as well as for marketing and commercialisation strategies in the rapidly evolving large-volume SC landscape.

CONTAINER SELECTION FOR A HIGHLY SENSITIVE DRUG PRODUCT: A SUCCESS STORY

Enrico Barichello

Stevanato Group

CONTAINER SELECTION FOR A HIGHLY SENSITIVE DRUG PRODUCT: A SUCCESS STORY

Enrico Barichello discusses Stevanato Group’s collaboration with a leading pharmaceutical company to identify a suitable container for a high-concentration monoclonal antibody. The partnership addressed key challenges and contributed to maintaining the drug’s stability and integrity throughout its lifecycle.

DRUG DELIVERY TRENDS FOR 2025

DRUG DELIVERY TRENDS FOR 2025

Tom Oakley and Alex Vasiev look back at how the trends anticipated for 2024 played out in reality and look forward to four major trends expected to influence the drug delivery industry in 2025.

EMPOWERING PHARMA WITH INNOVATIVE INFUSION TECHNOLOGIES AMID US POLICY CHANGES

EMPOWERING PHARMA WITH INNOVATIVE INFUSION TECHNOLOGIES AMID US POLICY CHANGES

Mindy Katz and Michael Ratigan outline the implications for pharmaceutical manufacturers of recent US policy changes – and highlight how Eitan Medical’s portfolio of infusion solutions can offer support.

510(k) CLEARED, USER-FILLED MICRODOSING DEVICE FOR OPHTHALMIC AND OTHER APPLICATIONS

PREFILLED SYRINGES

Dr Gautam Shetty

Congruence Medical Solutions

510(k) CLEARED, USER-FILLED MICRODOSING DEVICE FOR OPHTHALMIC AND OTHER APPLICATIONS

Gautam Shetty discusses unmet drug delivery needs in applications requiring accurate and precise microlitre-scale doses,going on to detail how the Congruence Medical’s recently cleared Microliter Dosing Syringe can bring the benefits of advanced syringe materials and performance to these applications.

TUB & NEST – PRECISION AND EFFICIENCY IN DRUG DELIVERY

PREFILLED SYRINGES

TUB & NEST – PRECISION AND EFFICIENCY IN DRUG DELIVERY

Ivana Thiesson and Jörg Sander applied marketing discuss the benefits of Fischer Söhne’s “Tub & Nest” format for packaging prefilled syringes, including design flexibility and precise cleanroom manufacturing.

UNLOCK VALUE: KEY COST DRIVERS IN SPRING AND STAMPING DESIGN

INDUSTRIALISATION

Rolando Abaroa Martinez

Baumann Medical

UNLOCK VALUE: KEY COST DRIVERS IN SPRING AND STAMPING DESIGN

Rolando Abaroa Martinez and David Pircher highlight how a metal parts supplier can help to optimise costs – not only for springs and stampings but also in later production stages of a medical device. With a focus on the design phase, they emphasise that not only the costs associated with the metal product but also the total costs can be managed effectively with the right support from experts.

THE ROLE OF METAL DEEP-DRAWN PARTS IN MEDICAL DEVICES FOR DRUG DELIVERY

INDUSTRIALISATION

Dennis Gossmann

STÜKEN Medical

THE ROLE OF METAL DEEP-DRAWN PARTS IN MEDICAL DEVICES FOR DRUG DELIVERY

Dennis Gossmann discusses the benefits of using deep-drawn metal components in drug delivery devices and how STÜKEN MEDICAL, as an established expert in this field, can be an ideal partner for manufacturing and supplying these parts.

HIGH-DOSE DRUG DELIVERY – HOW FAR CAN AUTOINJECTORS GO?

Dr Iain Simpson

Phillips Medisize

HIGH-DOSE DRUG DELIVERY – HOW FAR CAN AUTOINJECTORS GO?

Iain Simpson reviews the development of autoinjectors for self-injection and explains that, despite significant emerging trends for biologics, new developments in formulation and autoinjector technology may enable them to continue to be the dominant delivery device for these medications.

TESTING SYRINGES & INJECTION DEVICES: SOLUTIONS THAT BOOST EFFICIENCY

TESTING SYRINGES & INJECTION DEVICES: SOLUTIONS THAT BOOST EFFICIENCY

Peter Schmidt discusses ZwickRoell’s offerings in the arena of testing systems for injectable drug delivery systems, in particular highlighting the advantages of automation for providing reliable, reproducible results.

FROM PLATFORM TO PRODUCT: ACCELERATING TIME-TO-MARKET FOR PLATFORM TECHNOLOGIES

FROM PLATFORM TO PRODUCT: ACCELERATING TIME-TO-MARKET FOR PLATFORM TECHNOLOGIES

Fran Pencliffe explores the benefits of platform devices for parenteral delivery and outlines the challenges, risks and best practices when bringing a combination product to market in this way.

NOVEL SOLUTIONS FOR ULTRA-LARGE-VOLUME WEARABLE AND PORTABLE SUBCUTANEOUS INJECTORS

Dr Hong-Jun Yeh

MicroMED Co Ltd

NOVEL SOLUTIONS FOR ULTRA-LARGE-VOLUME WEARABLE AND PORTABLE SUBCUTANEOUS INJECTORS

Dr Hong-Jun Yeh, Jiunn-Ru Lai and Tsung-Chieh Cheng discuss the need for novel approaches to the challenge of delivering high volumes of biologics while also addressing patient centricity, and introduce MicroMED’s two innovative gas-powered approaches that leverage micro-electromechanical systems to drive the injection.

Interview: Sustainability at the Heart of Aptar Pharma’s Expansion

Audrey Chardonnet

Interview: Sustainability at the Heart of Aptar Pharma’s Expansion

Audrey Chardonnet discusses the centrality of sustainability to Aptar Pharma’s expansion strategy, going into detail on how, by improving its practices and investing in its infrastructure, the company works towards reducing the environmental impact of injectable drug delivery solutions manufacturing.

DEVICE SELECTION: INJECTION VOLUMES FOR SUBCUTANEOUS ADMINISTRATION

Dr Nicolas Brandes

DEVICE SELECTION: INJECTION VOLUMES FOR SUBCUTANEOUS ADMINISTRATION

Nicolas Brandes, Andrea Allmendinger and Hanns-Christian Mahler explore the critical considerations for subcutaneous injection volume, beginning with the historical and scientific perspectives on injection volume before delving into the challenges of determining volume ranges and their associated fill volumes.

VERSATILITY, SUSTAINABILITY AND DIGITALISATION IN ONE SMART HANDHELD INJECTION PLATFORM

VERSATILITY, SUSTAINABILITY AND DIGITALISATION IN ONE SMART HANDHELD INJECTION PLATFORM

Leonard Chu discusses three trends in self-administration that are aligned with emerging smart devices – device versatility, sustainability and digitalisation – and the benefits offered by the Alcee injection platform.

ELEVATING DIGITAL PATIENT SUPPORT: NOTHING MATTERS UNLESS IT CHANGES BEHAVIOUR

ELEVATING DIGITAL PATIENT SUPPORT: NOTHING MATTERS UNLESS IT CHANGES BEHAVIOUR

Ben Cox, Thomas Grant and Lara Zaki discuss the role of behaviour design in onboarding for self-injection devices and how a robust and balanced framework can enhance the patient experience, reduce injection errors and promote safe and effective use.

PICCOJECT – ADVANCING SELF-INJECTION OF HIGH-VISCOSITY FORMULATIONS

PICCOJECT – ADVANCING SELF-INJECTION OF HIGH-VISCOSITY FORMULATIONS

Thomas Thueer, Chris Muenzer and Stefanie Manger discuss the challenges posed to drug delivery device designers by the needs of biologic therapies. In response, Haselmeier has developed the PiccoJect autoinjector, which has a novel parallel spring layout that enables a newfound flexibility in design, ideally positioning it to rise to the challenges of delivering high-viscosity biologics.

BONDING TECHNOLOGIES FOR INJECTION DEVICES – A QUICK OVERVIEW

INDUSTRIALISATION

BONDING TECHNOLOGIES FOR INJECTION DEVICES – A QUICK OVERVIEW

Hisham Jamal and Carsten Köhler discuss some of the bonding technologies used for medical devices – highlighting their unique strengths, limitations and suitability.

NEXT-GENERATION AUTOINJECTORS: BALANCING PATIENTS, PHARMA, PAYERS AND PLANET

NEXT-GENERATION AUTOINJECTORS: BALANCING PATIENTS, PHARMA, PAYERS AND PLANET

David Latham, Matthew Allen and Charlie Dean use a case study of a reusable electromechanical autoinjector to outline the novel product development approach needed to achieve better outcomes for patients, pharma, payers and the planet.

Interview: Pharmapack Start-up Spotlight: InnoMedica Accelerating Trials with Novel Nanoparticle Filling

Pascal Halbherr

Interview: Pharmapack Start-up Spotlight: InnoMedica Accelerating Trials with Novel Nanoparticle Filling

Pascal Halbherr discusses the InnoMedica's innovative nanocarrier filling technology platform, its impact on biotech and drug delivery, and the company’s bold vision for the future. InnoMedica, a Swiss biotech, is one of the 28 early-stage companies presenting cutting-edge innovations in Pharmapack Europe 2025’s Start-up Market.

OPTIMISING CLINICAL TRIALS WITH AUTOINJECTORS: STRATEGIES FOR SUCCESS

PCI Pharma Services

OPTIMISING CLINICAL TRIALS WITH AUTOINJECTORS: STRATEGIES FOR SUCCESS

Bill Welch of PCI Pharma Services discusses the key considerations for integrating autoinjectors into clinical trial programmes, and the myriad benefits that doing so can bring for trial sponsors in terms of standardisation, data quality and patient-centricity.

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