Prefilled Syringes & Injection Devices105

Issue No #105 Feb 2020 February 3rd, 2020

Inside the magazine

ADDRESSING COMPLEX BIOLOGICS WITH RATIONAL DRUG DEVICE DESIGN

PREFILLED SYRINGES

Gene Rhode Fuensalida Pantig

ADDRESSING COMPLEX BIOLOGICS WITH RATIONAL DRUG DEVICE DESIGN

Gene Rhode Fuensalida Pantig reviews drug development over the years, the discovery of biologics as therapeutic agents and the emergence of autoinjectors, in correspondence with Hans Lin, PhD, a Research Fellow from Academia Sinica, Taiwan.

ENHANCING THE PATIENT EXPERIENCE FOR SELF-INJECTION SYSTEMS

PREFILLED SYRINGES

ENHANCING THE PATIENT EXPERIENCE FOR SELF-INJECTION SYSTEMS

The complexity of injectable treatment regimens for chronic diseases means onboarding aids can be integral to disease management. Joe Reynolds discusses the role of demonstration devices in improving the patient experience and adherence.

DRUG DELIVERY DESIGNED TO IMPROVE THE PATIENT EXPERIENCE

Enable Injections

DRUG DELIVERY DESIGNED TO IMPROVE THE PATIENT EXPERIENCE

Jennifer King looks at the delivery challenges of novel therapies for chronic diseases using a specific patient’s story as an example, going on to highlight the ways in which a novel device approach could make all the difference for patients.

HOW USERS DISTINGUISH BETWEEN SELF-INJECTION DEVICE PLATFORM VARIANTS

Dr Andreas Schneider

HOW USERS DISTINGUISH BETWEEN SELF-INJECTION DEVICE PLATFORM VARIANTS

Andreas Schneider highlights how the ever-increasing interest in device platforms raises concerns around the broad availability of lookalike autoinjectors that may result in inappropriate medication usage. He summarises a recent empirical study¹ providing insights into which device attributes drive device distinguishability.

OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE

PREFILLED SYRINGES

Mitsubishi Gas Chemical

OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE

Shota Arakawa and Tomohiro Suzuki, discuss the benefits of the OXYCAPT™ multilayer plastic vial and syringe for the rapidly growing field of biologics and regenerative medicines.

CHOOSING THE RIGHT LABEL MATERIAL FOR PREFILLED SYRINGES

CHOOSING THE RIGHT LABEL MATERIAL FOR PREFILLED SYRINGES

Jos van Noort outlines some of the key factors that must be taken into consideration when selecting a label for prefillable syringes.

NEXT-GENERATION WEARABLE DELIVERY DEVICES FOR LARGE-VOLUME BIOLOGICS

NEXT-GENERATION WEARABLE DELIVERY DEVICES FOR LARGE-VOLUME BIOLOGICS

Thomas Mayer discusses Sonceboz’s platform of wearable injection devices for large-volume biologics, which can follow drugs from clinical trials to commercial phase through lifecycle management, which reduces risk and speeds time to market.

EU MDR: ANCILLARY DELIVERY DEVICES FACE EQUAL SCRUTINY TO STANDALONE MEDICAL DEVICES

EU MDR: ANCILLARY DELIVERY DEVICES FACE EQUAL SCRUTINY TO STANDALONE MEDICAL DEVICES

Elizma Parry offers her expertise and practical guidance to businesses hoping to achieve a CE mark for a medical device, with new EU regulations being implemented this year.

PRODUCT SHOWCASE: ZwickRoell Parenteral Device Testing Platform

PREFILLED SYRINGES

Wolfgang Moersch

PRODUCT SHOWCASE: ZwickRoell Parenteral Device Testing Platform

ZwickRoell offers a wide variety of standardised test fixtures for parenteral devices including, described here: testing prefilled syringes to ISO 11040-4, -6 & -8; testing of Luer/Luer lock connections; serial, parallel and fully automatic syringe testing; and traceable, tamper-proof test results.

DEVELOPMENT OF A NEW HIGH-PERFORMANCE AUTOINJECTOR

DEVELOPMENT OF A NEW HIGH-PERFORMANCE AUTOINJECTOR

Tom Oakley and Sigrid Saaler-Reinhardt discuss the development of the Midas Pharma’s NIS cartridge-based autoinjector.

LARGE-VOLUME INJECTORS: RISE IN BIOLOGICS BRINGS CHALLENGES

Dr Paolo Fiorini

LARGE-VOLUME INJECTORS: RISE IN BIOLOGICS BRINGS CHALLENGES

Developing devices capable of delivering highly viscous biologic drug formulations at high volumes does not come without its challenges. Paolo Fiorini, Gerard Linnane, Michael Kiely, Maciej Grygorczuk and Joshua Coyne discuss these challenges and the merits of various drive solutions.

PREFILLED SAFETY SYRINGE MARKET THRIVES AMID SELF-ADMINISTRATION TREND

PREFILLED SAFETY SYRINGE MARKET THRIVES AMID SELF-ADMINISTRATION TREND

George I’ons looks at how the growing trend of patient self-administration is driving demand for prefilled safety syringes.

LEVERAGING THE PATIENT JOURNEY TO OPTIMISE DEVICE USE AT HOME

Séverine Duband

LEVERAGING THE PATIENT JOURNEY TO OPTIMISE DEVICE USE AT HOME

Séverine Duband and Mark Tunkel discuss the importance of device optimisation to increase patient safety during self-administration of medication.

ADDRESSING THE EVOLVING NEEDS OF VARIABLE DRUG DELIVERY REGIMENS

Dr Temitope Sodunke

BD (Becton Dickinson & Company)

ADDRESSING THE EVOLVING NEEDS OF VARIABLE DRUG DELIVERY REGIMENS

Temitope Sodunke introduces the BD Evolve™ On-body Injector and describes how the device is designed specifically to address the rapidly evolving needs of the pharma industry and meet patient requirements.

HOW TO DESIGN A BODY-WORN INJECTOR

Stephen Augustyn

HOW TO DESIGN A BODY-WORN INJECTOR

Body-worn injectors require you to understand your user, your drug and your technology – and there are numerous pitfalls for the unwary. Stephen Augustyn shares some insights.

THE NEED FOR CSTDS IN BOTH MANUAL AND AUTOMATED COMPOUNDING

THE NEED FOR CSTDS IN BOTH MANUAL AND AUTOMATED COMPOUNDING

Marino Kriheli discusses the benefits of using closed system transfer devices (CSTDs) in both manual and automated hazardous drugs compounding.

FINDING THE RIGHT PACKAGING FOR BIOLOGIC DRUGS

PREFILLED SYRINGES

Christian Helbig

FINDING THE RIGHT PACKAGING FOR BIOLOGIC DRUGS

Christian Helbig introduces a new 2.25 mL version of SCHOTT’s syriQ BioPure® prefillable syringes designed specifically for the biologics market and, developed in partnership with WL Gore, the world’s first silicone-free glass syringe system.

THE CHALLENGES OF A CHANGING MARKET & THE BENEFITS OF DEVELOPMENT FLEXIBILITY

THE CHALLENGES OF A CHANGING MARKET & THE BENEFITS OF DEVELOPMENT FLEXIBILITY

David Fink and Sheila Trgovac describe how adopting a flexible development model in mid-to-late development brings benefits through to commercialisation, especially in the context of a changing market.

VIDEO: Credence Connect from Credence MedSystems

Credence MedSystems

VIDEO: Credence Connect from Credence MedSystems

Credence MedSystems takes us through the use steps of its new Credence Connect™ autosensing injection system, and smartphone app.