Citation: Vogl M, “Gerresheimer Includes Stevanato Group Integrated Twist-Off Closure System for Gx RTF Syringes”. ONdrugDelivery, Issue 113 (Oct 2020), pp 77–78.
Maximilian Vogl reveals the latest user-friendly addition to its Gx® RTF Luer lock syringes using Stevanato Group’s integrated twist-off closure technology.
“The integrated seal cap consists of two components – an elastomeric component, which is available in different formulations, and a rigid, translucent polymer cap.”
Gerresheimer is to offer its Gx RTF (ready-to-fill) syringes with the SG ITC (integrated tip cap) twist-off closure from the Stevanato Group. With this technology, which is often asked for on the market, Gerresheimer is adding an especially user-friendly system solution for Luer lock syringes to its programme.
The integrated seal cap consists of two components – an elastomeric component, which is available in different formulations, and a rigid, translucent polymer cap. The elastomer component is inserted into the plastic cap, screwed together with a Luer lock adapter, and pre-assembled on the syringe. Compared with traditional Luer cone systems, this solution offers a syringe closure with increased stability, thus protecting the drug product.
The twist-off closure system (Figure 1) responds to the containment needs of different drugs: vaccines, hyaluronic acid, biotech drugs and other viscous formulations. It has been developed and produced according to the ISO 11040-7 standard and fits perfectly on Gx RTF syringes. Gerresheimer will offer 1.0 mL long and 1.0 mL short Luer lock syringes with the integrated twist-off closure as a first step (Figure 2), with additional formats to follow.
INCREASED SAFETY AND USER FRIENDLINESS
The seal cap is securely screwed onto the Gerresheimer Luer lock syringe, so that accidental removal of the cap is prevented (Figure 3). The familiar twist-off function offers medical specialists improved user friendliness without impairing the integrity of the prefillable syringes. The structured surface simplifies the removal of the cap.
The system components of Gerresheimer syringes are primarily aimed at user friendliness and safety – and the company says the new SG ITC twist-off closure suits these aims outstandingly. Gerresheimer already delivers syringes equipped with the seal cap, which can be processed on existing filling lines, under the name Gx TWILC (twistable integrated Luer lock closure). The 100-hole nests are packaged in a tub and sterilised with ethylene oxide gas (EtO).