| CONTENTS |
| Introductory Comment Guy Furness |
| Altea Therapeutics transdermal PassPort™ System: freedom from insulin injections for superior diabetes management Yogi R Patel Altea Therapeutics |
| The next generation insulin therapy David Brandt Anders Boss Mannkind Corporation |
| Company Profile Ypsomed |
| Oral-Lyn needle-free buccal delivery of insulin: a product whose time is now Gerald Bernstein Generex Biotechnology |