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INJECTION

A NOVEL PREFILLABLE SYRINGE WITH A GLASS PRIMARY CONTAINER BUT NO NEED FOR EXTREME THERMAL REFORMING
PREFILLED SYRINGES
Dr Stephen Shue
A NOVEL PREFILLABLE SYRINGE WITH A GLASS PRIMARY CONTAINER BUT NO NEED FOR EXTREME THERMAL REFORMING
Stephen Shue introduces a proprietary prefillable syringe, the SMPFS, whose novel glass-tube-plus-plastic-sheath design enables the use of a standard glass tube primary drug container, but avoids the need for the extreme thermal reforming process that conventional glass prefillable syringes must undergo.
UPDATE ON OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE
PREFILLED SYRINGES
Tomohiro Suzuki
Mitsubishi Gas Chemical
UPDATE ON OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE
Tomohiro Suzuki gives an update, including new oxygen barrier data, on the development of the OXYCAPT™ multilayer plastic vial and syringe.
SENSOR ADVANCEMENTS IN DRUG DELIVERY IMPROVE COMPLIANCE
EXPERT VIEW
Salvatore Forte
SENSOR ADVANCEMENTS IN DRUG DELIVERY IMPROVE COMPLIANCE
Salvatore Forte discusses various advancements in sensors that are transforming drug delivery systems, making complex devices more automated, easier to use, and improving patient compliance as a result.
Shorter Needles with Thinner Walls to Improve Injection Experience in Chronic Care
PREFILLED SYRINGES
Aurelie Pager
BD (Becton Dickinson & Company)
Shorter Needles with Thinner Walls to Improve Injection Experience in Chronic Care
Aurélie Pager, Brigitte Duinat and Barbara Alves look at how new BD Neopak™ XtraFlow™ prefillable syringes with shorter, 8 mm needles and thinner-wall cannula technology are set to improve the injection experience for subcutaneous drug delivery in chronic care.
WHICH IS THE BETTER TOXICITY TESTING STRATEGY FOR COMBINATION DEVICES?
EXPERT VIEW
Mark Turner
WHICH IS THE BETTER TOXICITY TESTING STRATEGY FOR COMBINATION DEVICES?
Mark Turner explores the issue of toxicity testing for combination devices and asks which is the better testing strategy – ISO 10993 or extractables and leachables?
DESIGN CONSIDERATIONS FOR IMPROVING TRAINING DEVICE SAFETY AND EFFECTIVENESS
EXPERT VIEW
Yvonne Limpens
DESIGN CONSIDERATIONS FOR IMPROVING TRAINING DEVICE SAFETY AND EFFECTIVENESS
Yvonne Limpens and Brenda van Geel, explore the design considerations that need to be taken into account when developing training devices that are safe and effective – and support patients in learning how to administer an injection correctly.
THE NEXT GENERATION OF COATED PLUNGERS
INJECTION
Carina Van Eester
Datwlyer
THE NEXT GENERATION OF COATED PLUNGERS
Carina Van Eester explores the benefits of fully coated plungers for prefilled syringes and cartridges.
APPLICATION OF CFD IN THE DEVELOPMENT OF A WEARABLE BOLUS INJECTOR
WEARABLES
Marcus Hall
APPLICATION OF CFD IN THE DEVELOPMENT OF A WEARABLE BOLUS INJECTOR
Marcus Hall, Björn Ullbrand and Claus Schmidt Møller describe the use of computational fluid dynamics (CFD) as the primary design and analysis tool in the development of a wearable bolus injector.
SUPPORTING IMPROVED PATIENT ONBOARDING & ADHERENCE WITH TRAINING SOLUTIONS
INJECTION
Bill Guilliouma
Noble
SUPPORTING IMPROVED PATIENT ONBOARDING & ADHERENCE WITH TRAINING SOLUTIONS
Bill Guilliouma looks at the role of platform training solutions for patient onboarding and adherence to treatment regimens.
EU MDR DEADLINE DELAY: WHAT DOES IT MEAN FOR THE MEDICAL DEVICE INDUSTRY?
EXPERT VIEW
Beth Crandall
EU MDR DEADLINE DELAY: WHAT DOES IT MEAN FOR THE MEDICAL DEVICE INDUSTRY?
With the compliance deadline for the EU Medical Device Regulation recently delayed by a year due to the novel coronavirus pandemic, Beth Crandall looks at what it means for the medical device industry.
SILICA RE-EMERGES AS POTENTIAL NUCLEIC ACID DELIVERY VECTOR
EXPERT VIEW
Nigel Theobald
SILICA RE-EMERGES AS POTENTIAL NUCLEIC ACID DELIVERY VECTOR
Nigel Theobald looks at the challenges of oligonucleotide delivery and explores approaches to overcome them.
Telemedicine gains acceptance amid the Covid-19 pandemic
Joe Reynolds
Noble
Telemedicine gains acceptance amid the Covid-19 pandemic
Noble highlights how telemedicine is poised to become a mainstream alternative to the traditional in-person methods of care delivery, with the covid-19 pandemic easing barriers to acceptance and introducing patients to the safety and convenience of telehealth technology.
MedinCell investigating role of long-acting antivirals to break chain of SARS-COV-2 viral transmission
MedinCell investigating role of long-acting antivirals to break chain of SARS-COV-2 viral transmission
With evidence indicating that the established antiparasitic ivermectin can kill coronavirus in a laboratory setting in under 48 hours, MedinCell has published data showing that long-acting formulations of ivermectin can be designed with varying doses and durations with its BEPO® technology and is investigating whether a long-acting product could be effective in breaking the chain of viral transmission.
Lexaria Bioscience Expands Pharma Division for development of Lipophilic Antivirals against COVID-19
Lexaria Bioscience Expands Pharma Division for development of Lipophilic Antivirals against COVID-19
Lexaria is to investigate how its patented DehydraTECH drug delivery technology could enhance delivery and effectiveness of certain antiviral drugs in the fight against coronavirus disease COVID-19.  Lexaria intends to expand collaboration with leading laboratories as soon as possible.
ADDRESSING COMPLEX BIOLOGICS WITH RATIONAL DRUG DEVICE DESIGN
PREFILLED SYRINGES
Gene Rhode Fuensalida Pantig
SHL Medical
ADDRESSING COMPLEX BIOLOGICS WITH RATIONAL DRUG DEVICE DESIGN
Gene Rhode Fuensalida Pantig reviews drug development over the years, the discovery of biologics as therapeutic agents and the emergence of autoinjectors, in correspondence with Hans Lin, PhD, a Research Fellow from Academia Sinica, Taiwan.
ENHANCING THE PATIENT EXPERIENCE FOR SELF-INJECTION SYSTEMS
PREFILLED SYRINGES
Joe Reynolds
Noble
ENHANCING THE PATIENT EXPERIENCE FOR SELF-INJECTION SYSTEMS
The complexity of injectable treatment regimens for chronic diseases means onboarding aids can be integral to disease management. Joe Reynolds discusses the role of demonstration devices in improving the patient experience and adherence.
DRUG DELIVERY DESIGNED TO IMPROVE THE PATIENT EXPERIENCE
WEARABLES
Jennifer Estep
Enable Injections
DRUG DELIVERY DESIGNED TO IMPROVE THE PATIENT EXPERIENCE
Jennifer King looks at the delivery challenges of novel therapies for chronic diseases using a specific patient’s story as an example, going on to highlight the ways in which a novel device approach could make all the difference for patients.
HOW USERS DISTINGUISH BETWEEN SELF-INJECTION DEVICE PLATFORM VARIANTS
INJECTION
Dr Andreas Schneider
Ypsomed
HOW USERS DISTINGUISH BETWEEN SELF-INJECTION DEVICE PLATFORM VARIANTS
Andreas Schneider highlights how the ever-increasing interest in device platforms raises concerns around the broad availability of lookalike autoinjectors that may result in inappropriate medication usage. He summarises a recent empirical study1 providing insights into which device attributes drive device distinguishability.
OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE
PREFILLED SYRINGES
Shota Arakawa
Mitsubishi Gas Chemical
OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE
Shota Arakawa and Tomohiro Suzuki, discuss the benefits of the OXYCAPT™ multilayer plastic vial and syringe for the rapidly growing field of biologics and regenerative medicines.
CHOOSING THE RIGHT LABEL MATERIAL FOR PREFILLED SYRINGES
EXPERT VIEW
Jos van Noort
CHOOSING THE RIGHT LABEL MATERIAL FOR PREFILLED SYRINGES
Jos van Noort outlines some of the key factors that must be taken into consideration when selecting a label for prefillable syringes.
NEXT-GENERATION WEARABLE DELIVERY DEVICES FOR LARGE-VOLUME BIOLOGICS
WEARABLES
Thomas Mayer
Sonceboz
NEXT-GENERATION WEARABLE DELIVERY DEVICES FOR LARGE-VOLUME BIOLOGICS
Thomas Mayer discusses Sonceboz’s platform of wearable injection devices for large-volume biologics, which can follow drugs from clinical trials to commercial phase through lifecycle management, which reduces risk and speeds time to market.
EU MDR: ANCILLARY DELIVERY DEVICES FACE EQUAL SCRUTINY TO STANDALONE MEDICAL DEVICES
EXPERT VIEW
Elizma Parry
EU MDR: ANCILLARY DELIVERY DEVICES FACE EQUAL SCRUTINY TO STANDALONE MEDICAL DEVICES
Elizma Parry offers her expertise and practical guidance to businesses hoping to achieve a CE mark for a medical device, with new EU regulations being implemented this year.
PRODUCT SHOWCASE: ZwickRoell Parenteral Device Testing Platform
PREFILLED SYRINGES
Wolfgang Moersch
ZwickRoell
PRODUCT SHOWCASE: ZwickRoell Parenteral Device Testing Platform
ZwickRoell offers a wide variety of standardised test fixtures for parenteral devices including, described here: testing prefilled syringes to ISO 11040-4, -6 & -8; testing of Luer/Luer lock connections; serial, parallel and fully automatic syringe testing; and traceable, tamper-proof test results.
DEVELOPMENT OF A NEW HIGH-PERFORMANCE AUTOINJECTOR
INJECTION
Tom Oakley
Midas Pharma
DEVELOPMENT OF A NEW HIGH-PERFORMANCE AUTOINJECTOR
Tom Oakley and Sigrid Saaler-Reinhardt discuss the development of the Midas Pharma’s NIS cartridge-based autoinjector.
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