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INJECTION

PREPARING FOR MASS VACCINATION
EXPERT VIEW
Andy Fry
PREPARING FOR MASS VACCINATION
Andy Fry and Stephen Blatcher discuss the need for a mass vaccination device in response to the 2020 covid-19 pandemic. In particular, the authors discuss the benefits and challenges of turning to needle-free injection technology as a solution.
HOW LONG CAN YOU HOLD THE DEVICE AGAINST THE SKIN? INSIGHTS FROM AN EMPIRICAL STUDY USING HAND-HELD AUTOINJECTORS
INJECTION
Dr Andreas Schneider
Ypsomed
HOW LONG CAN YOU HOLD THE DEVICE AGAINST THE SKIN? INSIGHTS FROM AN EMPIRICAL STUDY USING HAND-HELD AUTOINJECTORS
Andreas Schneider summarises recent empirical work investigating the ability of users of hand-held devices to complete longer injection times effectively. The study provides insights into the effects of injection duration on the force exerted by the user to hold the device against the injection site.
PACKAGING LINE FOR GSK AUTOINJECTORS: A CASE STUDY
INDUSTRIALISATION
Ivan De Sanzo
PACKAGING LINE FOR GSK AUTOINJECTORS: A CASE STUDY
Ivan De Sanzo describes a unique automated complete packaging line provided to GlaxoSmithKline for three different autoinjectors.
CONDUCTING EFFECTIVE AND INFORMATIVE EVALUATIONS OF INJECTION DEVICE PACKAGING
EXPERT VIEW
Allison Strochlic
CONDUCTING EFFECTIVE AND INFORMATIVE EVALUATIONS OF INJECTION DEVICE PACKAGING
Allison Strochlic and Andrea Dwyer discuss the often overlooked aspect of a combination product user interface: the packaging. With a specific look at injection devices, the authors cover how to perform proper human factors testing of a combination product’s packaging, and the advantages doing so can confer to a project.
HOW DIGITAL TECHNOLOGY CAN TRANSFORM CLINICAL TRIALS
CONNECTIVITY
Sheila Trgovac
HOW DIGITAL TECHNOLOGY CAN TRANSFORM CLINICAL TRIALS
Sheila Trgovac and Rebecca Ford suggest that now is the time for innovation in clinical trials – using a patient-centric approach whilst leveraging digital solutions to create a digital clinical trial ecosystem.
FROM DESIGN TO DISPOSAL: ACHIEVING SUSTAINABILITY IN MEDICAL DEVICES
SUSTAINABILITY
George I’ons
Owen Mumford
FROM DESIGN TO DISPOSAL: ACHIEVING SUSTAINABILITY IN MEDICAL DEVICES
George I’ons discusses the onus on the device design industry to move towards sustainable practices, including what this entails, how it might be achieved and what benefits sustainability may bring.
PHARMA’S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT
SUSTAINABILITY
Alex Catino
Noble
PHARMA’S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT
Alex Catino discusses current trends in the pharmaceutical industry in relation to environmental sustainability in healthcare.
PRODUCT SHOWCASE: ZwickRoell Luer Lock Testing System
SUSTAINABILITY
Wolfgang Moersch
ZwickRoell
PRODUCT SHOWCASE: ZwickRoell Luer Lock Testing System
Wolfgang Moersch provides an update on ZwickRoell's Luer Lock Testing System and describes the company's sustainability policies, it having been carbon neutral since 2014.
NANOTECHNOLOGY: A PATHWAY FOR SUSTAINABLE INNOVATION IN DRUG DEVELOPMENT
SUSTAINABILITY
Andrea Cusack
leon-nanodrugs
NANOTECHNOLOGY: A PATHWAY FOR SUSTAINABLE INNOVATION IN DRUG DEVELOPMENT
Andrea Cusack discusses how, by using bottom-up nanotechnology techniques, efficiencies can be found both in the development of new chemical entities and in the repurposing of existing drugs, and how these efficiencies translate into reduced energy requirements and therefore more sustainable industry practices.
SMART GOALS AND CONTINUOUS IMPROVEMENT FOR A RESILIENT SUSTAINABILITY STRATEGY
SUSTAINABILITY
Dirk Borghs
Datwlyer
SMART GOALS AND CONTINUOUS IMPROVEMENT FOR A RESILIENT SUSTAINABILITY STRATEGY
Dirk Borghs considers the obligation of the pharmaceutical sector to implement environmentally responsible practices, and discusses the steps Datwyler is taking in its efforts for sustainability.
PAVING THE WAY TO ZERO CARBON EMISSION COMBINATION PRODUCTS: THE YPSOMATE ZERO CASE STUDY
SUSTAINABILITY
Sebastian Gerner
Ypsomed
PAVING THE WAY TO ZERO CARBON EMISSION COMBINATION PRODUCTS: THE YPSOMATE ZERO CASE STUDY
Sebastian Gerner and Andreas Schneider discuss the relationship between the medical device industry and the global issue of plastic waste. The authors introduce YpsoMate Zero as a case study, Ypsomed’s net-zero carbon emission prefilled autoinjector.
SUSTAINABILITY AND DRUG DELIVERY DEVICES
EXPERT VIEW
Rob Veasey
SUSTAINABILITY AND DRUG DELIVERY DEVICES
Rob Veasey explores the environmental challenges facing the drug delivery device industry – and the opportunities they bring.
WEARABLE INJECTORS: LATEST DEVICES & RECENT TRENDS
EXPERT VIEW
Tom Oakley
WEARABLE INJECTORS: LATEST DEVICES & RECENT TRENDS
Wearable injection device expert Tom Oakley discusses recent trends in the space. He also takes a look at wearable injection devices currently on the market and considers the future of wearable injectors.
EASING PATIENT EXPERIENCE WITH INNOVATIVE LARGE-VOLUME WEARABLES
WEARABLES
Victoria Morgan
West Pharmaceutical Services
EASING PATIENT EXPERIENCE WITH INNOVATIVE LARGE-VOLUME WEARABLES
Victoria Morgan discusses the growing sector of wearable injectors, with a specific focus on West’s own SmartDose® injector and the value of fill-finish services.
STABILITY OF A WEARABLE INJECTOR POWERED BY OSMOSIS
WEARABLES
Jesper Roested
STABILITY OF A WEARABLE INJECTOR POWERED BY OSMOSIS
Jesper Roested and Tomas Gundberg present engineering test data on Subcuject’s wearable bolus injector, based on an osmotic drive system, demonstrating that the device presents a solution to the need for an inexpensive, mass-producible wearable injector.
ANDREI YOSEF, CEO, SORREL MEDICAL
INTERVIEW
Dr Andrei Yosef
Eitan Medical
ANDREI YOSEF, CEO, SORREL MEDICAL
In this exclusive interview, Andrei Yosef discusses Sorrel’s differentiated electro-mechanical, connected wearable injection platform, and two exciting recent milestones for the company, the opening of a state-of-the-art manufacturing facility and the signing of a significant partnership with a large pharma company.
MEETING THE NEED FOR HIGH-VOLUME DRUG DELIVERY WITH ON-BODY BOLUS INJECTORS
WEARABLES
Tsachi Shaked
MEETING THE NEED FOR HIGH-VOLUME DRUG DELIVERY WITH ON-BODY BOLUS INJECTORS
Tsachi Shaked shows how on-body injectors present a safe and viable solution for high-volume drug delivery.
EMERGING TRENDS IN WEARABLE DRUG DELIVERY
WEARABLES
Tony Bedford
Phillips Medisize
EMERGING TRENDS IN WEARABLE DRUG DELIVERY
Tony Bedford discusses the current state of the fledgling on-body injector market, including the difficulties of competing with autoinjectors in the <5 mL space, the potential on-body injectors have in oncology and Phillips-Medisize’s own developments in the on-body injector field.
SIMPLIFYING LARGE-VOLUME PATCH INJECTION FOR PHARMA AND PATIENTS
WEARABLES
Reto Jost
Ypsomed
SIMPLIFYING LARGE-VOLUME PATCH INJECTION FOR PHARMA AND PATIENTS
Reto Jost provides an update on the YpsoDose platform and its importance as the driver for the business unit’s new patch injector franchise.
THE NEW PATIENT-CENTRICITY
WEARABLES
Jennifer Estep
Enable Injections
THE NEW PATIENT-CENTRICITY
Jennifer Estep discusses the new pressures put on the healthcare system by the covid-19 pandemic, and how patients and healthcare providers alike are turning to patient-centric solutions to minimise risks and ease burdens.
TECHNOLOGY SHOWCASE: CCBio’s QuickDose
WEARABLES
Jimmy Fan
CC Bio
TECHNOLOGY SHOWCASE: CCBio’s QuickDose
CCBio is introducing a new era of wearable on-body medical devices. QuickDose, recently successfully developed with both patients and pharmaceutical industry partners in mind, contains all the necessary elements for an excellent on-body device, comprising three major technical achievements.
FROM FORMULATION TO MANUFACTURING: LIPID NANOPARTICLE mRNA VACCINES, GENE THERAPIES & OTHER NANOMEDICINES
INDUSTRIALISATION
Stephen Allan
Evonik
FROM FORMULATION TO MANUFACTURING: LIPID NANOPARTICLE mRNA VACCINES, GENE THERAPIES & OTHER NANOMEDICINES
Stephen Allan reviews the history and formulation advantages of lipid nanoparticles (LNPs) and addresses factors that should be considered by pharmaceutical companies during the CDMO selection process to help reduce regulatory risk, improve product performance and accelerate speed to market.
CUSTOMISING PLATFORM DEVICES: CHALLENGES & CONSIDERATIONS
INDUSTRIALISATION
Doug Boyd
CUSTOMISING PLATFORM DEVICES: CHALLENGES & CONSIDERATIONS
How do you choose the best delivery system for your drug? Doug Boyd explores the pros and cons of a cost-effective, off-the-shelf platform versus a custom drug delivery device, and discusses the challenges and considerations of customising an existing platform device.
MEETING QUALITY DEMANDS THROUGH INTEGRATED PRODUCTS & SERVICES
INDUSTRIALISATION
Lars Keinicke Hansen
Stevanato Group
MEETING QUALITY DEMANDS THROUGH INTEGRATED PRODUCTS & SERVICES
Lars Keinicke Hansen; Chiara Mussoi and Odra Pinato describe how the streamlining of processes and harmonisation of products and services can better serve pharmaceutical companies. A case study highlights how a unique combination of expertise in automation and glass primary packaging benefited pharma giant Merck Serono in a recent project.
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