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OCULAR

TRENDS IN ANTI-GLAUCOMA TOPICAL TREATMENTS
OCULAR
Rouven Kraus
Aero Pump
TRENDS IN ANTI-GLAUCOMA TOPICAL TREATMENTS
Rouven Kraus presents the case for multidose delivery systems rather than single-use disposables, and introduces Aero Pump’s Ophthalmic Multidose System.
EXPANDING CONNECTIVITY: ADD-ONS FOR OPHTHALMIC AND NASAL DELIVERY
CONNECTIVITY
Nemera
EXPANDING CONNECTIVITY: ADD-ONS FOR OPHTHALMIC AND NASAL DELIVERY
Nemera introduces the e-Novelia® and e-Advancia® add-ons for ophthalmic and nasal devices.
AN OPTIMISED PLATFORM FOR HIGHLY SENSITIVE BIOLOGICS
PREFILLED SYRINGES
Alessio Bonati
Stevanato Group
AN OPTIMISED PLATFORM FOR HIGHLY SENSITIVE BIOLOGICS
Alessio Bonati discusses the problematic interactions between drugs and their primary containers and goes on to introduce the Alba platform, Ompi’s range of primary glass containers designed to unify drug-container interactions over a product’s lifecycle.
SUSTAINED DRUG DELIVERY TO THE POSTERIOR SEGMENTS OF THE EYE
OCULAR
Dr Shikha P Barman
SUSTAINED DRUG DELIVERY TO THE POSTERIOR SEGMENTS OF THE EYE
Shikha Barman reviews approaches for delivering drugs for diseases of the back of the eye, and introduces EySite-InjecT™.
FANNY SELLIER, NEMERA
INTERVIEW
Fanny Sellier
Nemera
FANNY SELLIER, NEMERA
Talking here with ONDrugDelivery Magazine, Ms Sellier discusses Nemera’s multidose eyedropper system Novelia® for preservative-free formulations. She explains how this platform has been developed to improve patients’ lives.
AQUEOUS-FREE OPHTHALMIC DELIVERY TECHNOLOGY
OCULAR
Dr Christian Roesky
AQUEOUS-FREE OPHTHALMIC DELIVERY TECHNOLOGY
Traditional aqueous vehicles for topical ophthalmic medications suffer from a number of limitations. Christian Roesky reviews the benefits of EyeSol®, a proprietary aqueous-free drug delivery technology.
PHYSICOCHEMICAL BIOEQUIVALENCE IN OPHTHALMIC MICROEMULSIONS
EXPERT VIEW
Dr Paul Kippax
PHYSICOCHEMICAL BIOEQUIVALENCE IN OPHTHALMIC MICROEMULSIONS
Here, Paul Kippax describes the methods by which bioequivalence can be established for ophthalmic microemulsions by in vitro testing, saving the need for costly clinical trials.
USING PHYSICAL FORCES TO ENHANCE OCULAR DRUG DELIVERY
EXPERT VIEW
Di Huang
USING PHYSICAL FORCES TO ENHANCE OCULAR DRUG DELIVERY
Di Huang, Erica Chen and Ilva Rupenthal discuss the possibilities offered by physical force-based methods of enhancing the efficacy of ophthalmic drug delivery by providing a way past the eye’s natural barriers.
SUSTAINED RELEASE OCULAR THERAPEUTICS
EXPERT VIEW
Michael O'Rourke
SUSTAINED RELEASE OCULAR THERAPEUTICS
Michael O’Rourke gives an overview of the current state of the ophthalmics market, going into greater detail on the opportunities offered in the area of sustained-release technologies and therapies.
BIODEGRADABLE IMPLANTS FOR SUSTAINED INTRAOCULAR DELIVERY
OCULAR
Dr Raj Thakur
BIODEGRADABLE IMPLANTS FOR SUSTAINED INTRAOCULAR DELIVERY
Raj Thakur and Prof David Jones discuss the difficulty of treating diseases of the back and front of the eye, and introduce a possible solution: OcuLief™ and EyeLief™, Re-Vana’s two proprietary sustained-release platforms.
CREATING SUSTAINABLE BIOTHERAPEUTICS FACTORIES IN THE EYE
OCULAR
Dr Patricia Zilliox
CREATING SUSTAINABLE BIOTHERAPEUTICS FACTORIES IN THE EYE
Patricia Zilliox discusses the inherent difficulties in drug delivery to the back of the eye and how this creates an unmet need in ophthalmology. Dr Zilliox goes on to describe Eyevensys’ novel solution to this problem, and the company’s first lead product, EYS606.
A TOPICAL OCULAR RING DESIGNED TO REPLACE GLAUCOMA EYE DROPS
OCULAR
Anne Brody Rubin
A TOPICAL OCULAR RING DESIGNED TO REPLACE GLAUCOMA EYE DROPS
Anne Brody Rubin introduces ForSight VISION5's ring-shaped ocular insert containing prostaglandin for the lowering of intra-ocular pressure in glaucoma.
OPSISPORIN: A LONG-ACTING DRUG DELIVERY APPROACH FOR UVEITIS
OCULAR
Dr Paul Seaman
OPSISPORIN: A LONG-ACTING DRUG DELIVERY APPROACH FOR UVEITIS
Here, Paul Seaman and Daniel Palmer discuss Midatech Pharma’s next generation treatments for auto-immune ocular diseases, which use a combination of innovative, sustained-release drug products.
NEW SOLUTIONS FOR OPHTHALMIC DRUG DELIVERY USING BIODEGRADABLE SILICA MATRIX
OCULAR
Dr Mika Jokinen
NEW SOLUTIONS FOR OPHTHALMIC DRUG DELIVERY USING BIODEGRADABLE SILICA MATRIX
Mika Jokinen, Cora Griffin, and Lasse Leino, PhD describe the novel opportunities that biodegradable silica matrix technology offers to ophthalmic drug delivery.
IMPROVING OPHTHALMIC DRUG DELIVERY WITH NOVEL EMULSION TECHNOLOGIES
OCULAR
Robin de Bruijn
IMPROVING OPHTHALMIC DRUG DELIVERY WITH NOVEL EMULSION TECHNOLOGIES
Robin de Bruijn and Frank de Jong describe EmulTech’s ET4ME micro-encapsulation process, and its suitability as a particle formation technology for enhancing and enabling ophthalmic injectables.
USING INTELLIGENT DESIGN TO DELIVER SAFE MULTI-DOSE EYE DROPS
OCULAR
Fanny Sellier
Nemera
USING INTELLIGENT DESIGN TO DELIVER SAFE MULTI-DOSE EYE DROPS
Ms Fanny Sellier, explains how the intelligent design of multi-dose bottles provides a viable means of delivering safe, preservative-free eye drops.
SUSTAINED-RELEASE OCULAR DELIVERY TECHNOLOGIES
EXPERT VIEW
Michael O'Rourke
SUSTAINED-RELEASE OCULAR DELIVERY TECHNOLOGIES
Michael O'Rourke discusses the advances in the development and launching of sustained-release ocular drug delivery systems seen in recent years.
SCALEABILITY OF MICRO INTRAOCULAR IMPLANTS AND DEVICES
OCULAR
Donna Bibber
SCALEABILITY OF MICRO INTRAOCULAR IMPLANTS AND DEVICES
Donna Bibber discusses some of these micro-intraocular implants and devices and the scalability challenges associated with each, from the perspective of a plastics engineer.
THERAPY WITHOUT DROPS: A REALITY
OCULAR
Chris Muller
THERAPY WITHOUT DROPS: A REALITY
Chris Muller and Deepank Utkhede introduce Mati Therapeutics' Evolute® ocular delivery system, a non-invasive, sustained-release platform that combines a novel punctal plug with a sustained release drug eluting core.
INTRODUCING OCUSURF™ NANOSTRUCTURED EMULSION AS A 505(B)(2) STRATEGY
OCULAR
Dr Shikha P Barman
INTRODUCING OCUSURF™ NANOSTRUCTURED EMULSION AS A 505(B)(2) STRATEGY
Shikha P Barman describes how Integral Biosystems is developing a series of ophthalmic products with its OcuSurf platform.
PSIVIDA AND OPHTHALMIC DRUG DELIVERY
OCULAR
Dr Paul Ashton
EyePoint Pharmaceuticals
PSIVIDA AND OPHTHALMIC DRUG DELIVERY
Paul Ashton describes how much of the progress that has been made recently in the treatment of ophthalmic diseases can be ascribed to effective drug delivery systems, and outlines some of the delivery technologies and resulting products for which pSivida has been responsible.
MODELLING OCULAR DELIVERY USING COMPUTATIONAL FLUID DYNAMICS
OCULAR
Dr Marc Horner
ANSYS, Inc
MODELLING OCULAR DELIVERY USING COMPUTATIONAL FLUID DYNAMICS
Paul Missel and Marc Horner describe the use of computational fluid dynamics simulations to predict drug flow and temperature inside the eye, and provide examples of applications modelling.
HUGE THERAPEUTIC ADVANCES: BIGGER DRUG DELIVERY OPPORTUNITIES
EXPERT VIEW
Dr Paul Ashton
HUGE THERAPEUTIC ADVANCES: BIGGER DRUG DELIVERY OPPORTUNITIES
Paul Ashton gives an introduction into the current state of the ophthalmics market.
AN INTEGRATED PIPELINE OF OPHTHALMIC PRODUCTS BASED ON EYESOL™ DELIVERY TECHNOLOGY
OCULAR
Dr Dieter Scherer
AN INTEGRATED PIPELINE OF OPHTHALMIC PRODUCTS BASED ON EYESOL™ DELIVERY TECHNOLOGY
Dieter Scherer describes two of Novaliq’s most advanced products: NovaTears®, a wetting agent for the ocular surface, and CyclASol®, a clear formulation of Cyclosporin A. Both products use Novaliq’s semifluorinated alkane technology, EyeSol®.
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