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Pulmonary & Nasal Delivery114

Issue No #114 Nov 2020  November 27th, 2020


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Inside the magazine

AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING
PULMONARY
Frédérique Bordes-Picard
Lonza
AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING
Frédérique Bordes-Picard and Julien Lamps discuss the factors driving development in the area of capsule-based dry powder inhalers, and how the company’s Capsugel® Zephyr™ portfolio offering is perfectly positioned to meet and exceed industry’s growing and evolving requirements.
DEVELOPMENT & PRODUCTION OF RESPIMAT<sup>®</sup> REUSABLE INHALER HOUSING MODULE
RESPIRATORY
Josef Schmid
Gerresheimer
DEVELOPMENT & PRODUCTION OF RESPIMAT® REUSABLE INHALER HOUSING MODULE
Josef Schmid, Markus Müller and Nina Zielonka discuss Gerresheimer’s recent work on developing the housing module for Boehringer Ingelheim’s new version of the Respimat inhaler.
AN INTRODUCTION TO SMART BREATH-ACTUATED NEBULISERS
PULMONARY
Edgar Hernan Cuevas Brun
HCmed Innovations
AN INTRODUCTION TO SMART BREATH-ACTUATED NEBULISERS
Edgar Hernan Cuevas Brun considers the benefits of smart breath-actuated nebulisers and looks at the latest technology contributing to the evolution of nebulisers.
ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS
INDUSTRIALISATION
Bert Dekens
Hosokawa Micron BV
ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS
Bert Dekens discusses Hosokawa Micron's offering for pharmaceutical powder mixing, including the Cyclomix high-shear mixer and the Nauta low-shear mixer, and how the company’s technology solutions take a broader approach to the full mixing process than simply providing a mixing machine.
INTRANASAL DELIVERY OF BIOLOGIC THERAPEUTICS AND VACCINES
NASAL
David Ward
Intertek Pharmaceutical Services
INTRANASAL DELIVERY OF BIOLOGIC THERAPEUTICS AND VACCINES
David Ward looks at how the nasal route of drug administration offers the potential to improve the delivery of biologics, even for very complex molecules such as antibodies – and why strategic formulation is required to make this a reality.
SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES
PULMONARY
João Pereira
Hovione
SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES
João Pereira, Raquel Borda D’Água, Mark Copley and Anna Sipitanou, discuss the semi-automation of cascade impactor testing and the benefits it can bring in terms of quality of orally inhaled product test data, and reductions in cost and effort associated with routine, critical measurements.
COLD FILLING VERSUS PRESSURE FILLING: THE CASE FOR VERSATILE, FULLY INTEGRATED CDMOs
RESPIRATORY
Steve Haswell
Kindeva Drug Delivery
COLD FILLING VERSUS PRESSURE FILLING: THE CASE FOR VERSATILE, FULLY INTEGRATED CDMOs
Steve Haswell compares the two main processes for manufacturing pressurised metered dose inhalers – and examines the value for pharmaceutical companies of working with contract development and manufacturing organisations that have expertise in both processes.
ECONOMIC OPERATORS UNDER THE EU MDR: THE NEW REQUIREMENTS
EXPERT VIEW
Beth Crandall
ECONOMIC OPERATORS UNDER THE EU MDR: THE NEW REQUIREMENTS
Beth Crandall spells out the new requirements for Economic Operators under the EU Medical Device Regulation.
PULMO<emp>CRAFT</emp>™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY
PULMONARY
Dr Richard Johnson
Upperton Pharma Solutions
PULMOCRAFT™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY
Richard Johnson discusses the techniques of jet milling and spray drying for the production of formulations for dry powder inhalers, and introduces Upperton Pharma’s PulmoCraft™ technology, which combines the advantages of both.
EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES
PULMONARY
Dr Sion Coulman
Cardiff University
EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES
Sion Coulman, Siamac Parker, Prof James Birchall, Susana Ecenarro and Mahmoud Farag discuss new developments in low moisture content capsule technology for hygroscopic and very moisture-labile APIs.
THE UNTOLD STORY OF NEMERA’S INHALATION FRANCHISE
RESPIRATORY
Raphaële Audibert
Nemera
THE UNTOLD STORY OF NEMERA’S INHALATION FRANCHISE
Raphaële Audibert and Niyati Sapatnekar tell the story of Nemera’s journey from contract manufacturer to end-to-end inhalation partner.
HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY
RESPIRATORY
Howard Burnett
Aptar Pharma
HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY
Howard Burnett explores how emotional intelligence can foster partnerships that have the potential to drive advances in understanding and improving patient outcomes, and presents the case for a single-source, turnkey approach to pulmonary solution development.
MG2 AUTOMATION SOLUTIONS FOR INHALATION: R&D, TECHNOLOGICAL PARTNERSHIPS & SUCCESSFUL CASE HISTORIES
PULMONARY
MG2
MG2 AUTOMATION SOLUTIONS FOR INHALATION: R&D, TECHNOLOGICAL PARTNERSHIPS & SUCCESSFUL CASE HISTORIES
Italian automation solutions provider MG2 describes its offering in the inhalation space, including unique benefits of collaboration and two example partnerships.
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