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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
CONTRIBUTE
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INJECTION
WEARABLES
Ian Thompson
Ypsomed
YPSODOSE – SIMPLIFYING LARGE-VOLUME PATCH INJECTIONS
Ian Thompson provides the latest insights into the YpsoDose prefilled and pre-assembled patch injector as it moves into the industrialisation phase for clinical trials.
WEARABLES
Atul Patel
West Pharmaceutical Services
THE PATH TO COMMERCIALISATION FOR WEARABLE DRUG DELIVERY DEVICES
Atul Patel looks at the evolution of the wearable drug delivery market, including the route to commercialisation and the challenges faced.
WEARABLES
Alice Bogrash
Eitan Medical
DESIGNING DRUG DELIVERY DEVICES THROUGH COLLABORATIVE USABILITY TESTING
Alice Bogrash examines how the company uses human factors studies to design drug delivery devices that respond to user needs, while providing a competitive advantage for pharmaceutical companies looking to introduce innovative combination products to the market.
WEARABLES
Tony Bedford
Phillips Medisize
MEETING EMERGING STAKEHOLDER NEEDS WITH THE SUBCUJECT WEARABLE BOLUS INJECTOR
Tony Bedford looks at the emerging market for on-body injectors coupled with stakeholder needs and introduces the Subcuject wearable bolus injector, which is designed to accommodate these requirements.
WEARABLES
Séverine Duband
Nemera
TACKLING HIGH-VOLUME ADMINISTRATION CHALLENGES WITH A SMART, SUSTAINABLE ON-BODY INJECTOR PLATFORM
Séverine Duband introduces Symbioze, Nemera’s novel on-body injector platform device, comprising a reusable main unit and disposable prefilled drug container, and offering a balance between the need to deliver advanced formulations at high volumes and the desire for patient-centric ease-of-use that enables patients to self-administer their therapies at home.
WEARABLES
Steffen Reuter
HIGH PRECISION IN PLASTICS IMPROVES THE QUALITY OF LIFE OF DIABETES PATIENTS
Steffen Reuter discusses the importance of high precision when manufacturing injection moulded components for wearable insulin delivery devices, with particular reference to three such parts from a recent project as a case study for Weidmann Medical Technology’s approach.
EXPERT VIEW
Enrico Denna
USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN
Enrico Denna looks at the advantages of a simulation and modelling approach over prototyping for the design of medical products.
WEARABLES
Roger Nordy
COMPLEXITY OF PATCH PUMP ASSEMBLY AND CONSIDERATIONS FOR MASTERING IT
Roger Nordy discusses the complexities of patch pump assembly and explains how ATS has been mastering the intricacies of the automation process to take on the growing industry demand.
WEARABLES
Wim Vos
Celanese
VECTRA
®
MT
®
LCP BRINGS THE ADVANTAGES OF LIQUID CRYSTAL POLYMERS TO WEARABLE INJECTORS
Wim Vos, Dave Pellegrino and Rob Haley discuss the myriad benefits of Vectra
®
MT
®
LCP, Celanese’s medical-grade liquid crystal polymer, for wearable injection devices, including improved patient comfort, greater design flexibility and reduced processing costs.
WEARABLES
Thomas Mayer
Sonceboz
REPOSITIONING FROM IV TO VIAL-BASED SC FOR LARGE-VOLUME BIOLOGICS
Tom Mayer discusses the growing trend of moving away from intravenous drugs administered in clinical and hospital settings to at-home, self-administered vial-based subcutaneous delivery for cost savings, better lifecycle management and improved care.
EXPERT VIEW
Tim Resker
OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES
Tim Resker looks at new technologies for powering on battery-operated drug delivery devices while considering battery drain, ingress protection and user-friendliness.
EXPERT VIEW
Shaun Devitt
EXTENDING CONTAINER CLOSURE INTEGRITY TO WEARABLE INJECTORS
Shaun Devitt looks at how the principles and methods of container closure integrity might be adapted for wearable injectors.
WEARABLES
Matthew Huddleston
Enable Injections
DRUG DELIVERY: WHAT DO PATIENTS AND PROVIDERS WANT?
Matthew Huddleston and Jennifer Estep discuss current drug delivery options and the value of convenient care.
CONNECTIVITY
Marcus Jarman-Smith
Victrex
CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS
Marcus Jarman-Smith, Adam Salmen, John Devine, Ernst Hupkes and Dennis Freie discuss the value of PEEK, a high-performance polymer, in drug delivery device design, using two concept devices – an on-body patch pump and vaporiser inhaler.
INDUSTRIALISATION
Lucy Chung
SHL Medical
DEVELOPING A FULLY AUTOMATED MODULAR MACHINE PLATFORM FOR AUTOINJECTOR TESTING
Lucy Chung and Gilbert Fluetsch discuss the benefits of a modular automated test platform.
EARLY INSIGHT
Dr Antonio Costa
ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES
Antonio Costa discusses the use of lipid nanoparticles in the modern drug delivery industry and introduces the DIANT system for the continuous processing of nanoparticles with integrated process analytical technology, which can provide the quality required for these injectable, complex formulations.
INDUSTRIALISATION
Sam Eubanks
BD (Becton Dickinson & Company)
THE FUTURE OF CONTAINER-LEVEL TRACEABILITY FOR PREFILLABLE SYRINGES
Sam Eubanks and Hervé Soukiassian discuss the BD traceability solution. This concept under development aims to deliver traceability at the unique container level from manufacture to the point of care.
INDUSTRIALISATION
Jens Schou Christensen
Stevanato Group
HOW DIGITISATION IS DELIVERING COMPETITIVE ADVANTAGE IN DEVICE ASSEMBLY
Jens Schou Christensen and Sebastian Berninger-Lund present the business case for the wider implementation of digitisation and the greater use of data to deliver assembly line improvements.
INDUSTRIALISATION
John Swift
Owen Mumford
PUTTING POST-PANDEMIC SUPPLY CHAINS TO THE TEST
John Swift discusses the need for medtech companies to undertake a reappraisal of their supply chains in light of covid-19, taking into consideration how the pandemic has exposed vulnerabilities that have previously gone unnoticed or ignored.
INDUSTRIALISATION
Napoleon Monroe
New Directions Technology Consulting
INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING
Napoleon Monroe considers the impact of the changing technological landscape on how industrialisation in the healthcare industry is evolving, with reference to the idea of “patients as consumers” and how the relationship between consumers, information and industry has evolved in other sectors, such as tech and retail – and how big players in those sectors are looking to move into and disrupt healthcare.
INDUSTRIALISATION
Hiroki Hasegawa
Mitsubishi Gas Chemical
UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE
Hiroki Hasegawa and Tomohiro Suzuki discuss the advantages of OXYCAPT™ multilayer plastic vial and syringe, which combine the benefits of cyclo-olefin polymer with excellent oxygen and UV barrier properties. In particular, the authors focus on recent studies that highlight OXYCAPT’s very low levels of extractables.
EXPERT VIEW
Richard Gray
AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE
Richard Gray and Julia Rashba-Step discuss the benefits of automated lipid nanoparticle production.
CONNECTIVITY
Arnaud Guillet
Biocorp
BIOCORP’S MALLYA – CHRONICLING A SUCCESS STORY
Arnaud Guillet and colleagues from across the industry, discuss Bicorp’s Mallya add-on device for disposable insulin pens, providing details on the main country launches and key software integrations, as well as presenting initial feedback from healthcare professionals and patients.
CONNECTIVITY
Napoleon Monroe
New Directions Technology Consulting
PATENTS ARE IMPORTANT FOR SMART HEALTHCARE PRODUCTS
Napoleon Monroe discusses the value of internet-connected smart devices in present-day healthcare, and introduces the mMed patent portfolio, of which Mr Monroe is the sole inventor, and which contains five US patents for key connected health technologies.
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