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INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
SKIN
SUSTAINABILITY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
MEDIA PACK
CONTRIBUTE
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INJECTION
SUSTAINABILITY
Barbara Lead
SMC Ltd
SUSTAINABILITY CONSIDERATIONS FOR END-TO-END DRUG DELIVERY DEVICE SOLUTIONS
Barbara Lead outlines the sustainability efforts undertaken by SMC Group associated companies, including facilitating the transition from hospital to at-home treatment and investment in greener facilities.
OCULAR
Dr Andrea Allmendinger
ten23 health
HOW TEN23 HEALTH IS MEETING DEVELOPMENTAL CHALLENGES FOR INTRAVITREAL PRODUCTS
Andrea Allmendinger and Hanns-Christian Mahler highlight new regulatory and quality requirements for intravitreal applications and discuss technical challenges during drug product technical development and manufacturing.
EXPERT VIEW
Dr Jay S Duker
ENVISIONING NEW HORIZONS IN OCULAR DRUG DELIVERY
Jay S Duker discusses the history and future of ocular drug delivery, with a special focus on posterior segment diseases and the battle to overcome significant patient and caregiver burdens.
OCULAR
Dr Gautam Shetty
Congruence Medical Solutions
OPHTHALMIC INJECTION OF VISCOUS FORMULATIONS – WHY UNIQUE NEEDS REQUIRE A NOVEL DELIVERY APPROACH
Guatam Shetty and Richard Whelton outline the key considerations related to ophthalmic injection of viscous formulations and propose an innovative, user-validated and fully mechanical device-based solution.
EXPERT VIEW
Michael Neely
A VIEW ON THE USE OF APROTIC SOLVENTS IN PARENTERAL DRUG FORMULATIONS
Michael Neely presents a review and discussion of the status of aprotic solvents as a solubilising vehicle for parenteral drug formulations in the context of the industry’s increasing interest in biologic drugs.
INDUSTRIALISATION
Rob Doorakkers
IGS GeboJagema
HOW MODEL BASED DEFINITION REVOLUTIONISES THE PRODUCTION OF MEDICAL DEVICES
Rob Doorakkers looks at the advantages of the IGS GeboJagema’s Model Based Definition process and its ability to improve the quality of medical device production.
INJECTION
Asmita Khanolkar
SMC Ltd
COMPUTATIONAL MODELLING OF INJECTION-RELATED TISSUE RESPONSES IN DRUG DELIVERY
Olivia Jefferies, Elizabeth Margerison and Asmita Khanolkar introduce Oval’s work on using ultrasound scanning and finite element analysis to construct a model of how tissue compresses under use of an autoinjector across patient demographics, and how this may provide insights into improved autoinjector design for more accurate injection depths, improving patient outcomes.
EXPERT VIEW
Tom Oakley
DRUG DELIVERY DEVICE TRENDS FOR 2022
Tom Oakley looks at some of the current trends in the drug delivery industry and projects some of the key factors that will influence drug delivery decision making in 2022.
SUSTAINABILITY
Michael Earl
Owen Mumford
SO FAR SO GOOD: MAINTAINING THE MOMENTUM OF PROGRESS FOR SUSTAINABLE POLICIES
Michael Earl discusses the highlights of a review undertaken by Owen Mumford into how the pharmaceutical industry is faring on environmental, social and governance standards, noting that while the industry is performing above average overall, there remain some key areas for improvement.
EXPERT VIEW
Salvatore Forte
VOICE-ACTIVATED USER INTERFACES IN DRUG DELIVERY DEVICES CAN ENHANCE COMPLIANCE AND OUTCOMES
Salvatore Forte looks at the evolution of voice-activated interfaces in medical devices, particularly autoinjectors, and the advantages for patient compliance and quality of care.
EXPERT VIEW
Dr Celeste Maksim
MDR COMPLIANCE: PLANNING FOR POST-MARKET CLINICAL FOLLOW-UP
Celeste Maksim discusses best practices for drug delivery device manufacturers when conducting post-market clinical follow-up activities, as mandated by the EU Medical Device Regulation.
PREFILLED SYRINGES
Michelle Deutsch
SCHOTT Pharma
TAKING INTEGRATED NEEDLE SAFETY SYSTEMS FOR PREFILLED SYRINGES TO THE NEXT LEVEL
Michelle Deutsch and John Merhige discuss the needle safety requirements of prefilled syringes and consider how SCHOTT TOPPAC
®
and syriQ
®
PFS with Credence Companion
®
technology combine to meet these challenges, while ensuring the device meets sustainability demands.
PREFILLED SYRINGES
Victoria Meyer
BD (Becton Dickinson & Company)
NEW BD SCF™ PREMIUMCOAT
®
1MLL PLUNGER STOPPER: GLIDING TOWARDS DE-RISKED COMBINATION PRODUCT DEVELOPMENT
Victoria Meyer introduces the BD SCF™ PremiumCoat
®
1mlL Plunger Stopper and explains how the product’s role is critical in determining combination products’ exposure to extractables and leachables.
PREFILLED SYRINGES
Dr Martin Gonzalez
Pfizer CentreOne
FROM VIAL TO PREFILLED SYRINGE: MIGRATING A DRUG PRODUCT PRESENTATION
Martin Gonzalez discusses some of the most relevant engineering activities that are necessary to transfer a product successfully from a vial into a prefilled syringe presentation.
PREFILLED SYRINGES
Yoshiko Sakuma
Mitsubishi Gas Chemical
PHOTO-STABILITY TESTS OF EPINEPHRINE
Yoshiko Sakuma and Tomohiro Suzuki provide an overview of OXYCAPT multilayer vial and syringe, with a particular emphasis on the advantages of OXYCAPT as a container for adrenaline, as demonstrated by recent studies conducted by MGC.
CONNECTIVITY
Dr Andreas Alt
Sensirion
HOW MINIATURISED LIQUID FLOW SENSORS ARE REVOLUTIONISING SUBCUTANEOUS DRUG DELIVERY
Andreas Alt and Susanne Pianezzi describe the drivers accelerating industry trends towards both wearable subcutaneous injection devices and connecting such devices to monitor patient dosing, providing a number of benefits.
CONNECTIVITY
Miriam Kingsley
Victrex
MATERIAL SELECTION FOR NEXT-GENERATION CONNECTED MEDICAL ELECTRONICS
Miriam Kingsley, Marcus Jarman-Smith and Thomas Billings highlight the growing array of applications for high-performance polymers in electronic and connected medical devices and how proper material selection is crucial, providing a guide to successful material selection, going on to showcase its APTIV™ PEEK polymer film, which is well suited to meet the specific demands of next-generation connected medical devices.
INTERVIEW
Arnaud Guillet
Biocorp
Interview: Arnaud Guillet, Biocorp
In this exclusive interview with ONdrugDelivery, Arnaud Guillet discusses Mallya, Biocorp’s connected clip-on for pen injectors, including Mallya’s successful launch in multiple countries this year, the factors that have played into the device’s success, and the future for Mallya, Biocorp and connectivity in the drug delivery industry.
CONNECTIVITY
Philippe Müller
Ypsomed
YPSOMATE ON – GO FOR SIMPLY CONNECTED
Philippe Müller and Silas Mächler discuss the benefits of integrated digital therapy management systems and the role of YpsoMate On – the newest addition to Ypsomed’s connected device portfolio, and the world’s first prefilled autoinjector with integrated connectivity that automatically logs injections on the user’s therapy management app.
CONNECTIVITY
Rebecca Beck
BD (Becton Dickinson & Company)
TRIALS WITHOUT TRIBULATIONS: A PATIENT-CENTRIC, CONNECTED INJECTION DEVICE FOR DECENTRALISED AND HYBRID CLINICAL TRIALS
Rebecca Beck and Hervé Monchoix discuss how stakeholder needs are driving the development of a new, connected injection device from BD, to support decentralised and hybrid clinical trials.
ROUNDTABLE
Sebastian Gerner
Alliance to Zero
ROUNDTABLE: ALLIANCE TO ZERO
Sebastian Gerner, Robert O’Beirn and Sabrina Gérard talk with ONdrugDelivery about the Alliance to Zero, an association for pharma and biotech supply chain companies that aims to facilitate the transition of the pharma sector to compliance with net-zero emissions.
SUSTAINABILITY
Peter Soelkner
Vetter Pharma
STRATEGIES TO ACHIEVE LONG-TERM SUSTAINABILITY
Peter Soelkner and Thomas Otto discuss how the pharmaceutical service provider focuses on sustainability.
SUSTAINABILITY
Emil Fraenkel
Phillips Medisize
SUSTAINABILITY WITH THE ARIA AUTOINJECTOR: A LIFECYCLE ASSESSMENT
Emil Fraenkel and Bjarne Sørensen consider the sustainability of re-usable and disposable autoinjectors, its implications in adding connectivity to drug delivery devices and how it has been an important consideration for Phillips-Medisize in the development of the Aria re-usable autoinjector.
SUSTAINABILITY
Frederick Gertz
SHL Medical
DATA-DRIVEN SUSTAINABILITY IN AUTOINJECTOR DEVELOPMENT
Frederick Gertz and Yves Steffen outline the company’s approach to sustainability, involving leveraging the experience of its data science department to enhance the output of its sustainability department.
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