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EXPERT VIEW

NEBULISERS: TIME TO REINVENT THE WHEEL
EXPERT VIEW
Dr John N Pritchard
NEBULISERS: TIME TO REINVENT THE WHEEL
John Pritchard discusses the history of the nebuliser, its fall in popularity with the advent of DPIs and pMDIs, and its current resurgence due to the success of the mesh nebuliser, continuing on to how changing the development paradigm to utilise nebuliser technology more effectively can have significant benefits.
PIPELINE TRENDS AND CHALLENGES IN PULMONARY DELIVERY
EXPERT VIEW
Dr Gunilla Petersson
PIPELINE TRENDS AND CHALLENGES IN PULMONARY DELIVERY
Gunilla Petersson provides an overview of the inhalables sector from a pharma perspective, covering the three major device types – DPIs, pMDIs and nebulisers.
MARKET CHALLENGES AND OPPORTUNITIES FOR DELIVERY SYSTEMS AND INJECTION DEVICES
EXPERT VIEW
Massimo Mainetti
MARKET CHALLENGES AND OPPORTUNITIES FOR DELIVERY SYSTEMS AND INJECTION DEVICES
Massimo Mainetti presents a brief overview of the current state of play in the field of novel biologic medicines as they relate to drug delivery.
PLATFORM DEVICES AND THE PATIENT JOURNEY
EXPERT VIEW
Mark Tunkel
PLATFORM DEVICES AND THE PATIENT JOURNEY
Mark Tunkel discusses the benefits of mapping the patient journey when looking to select a platform device for a new drug-device combination product.
PATIENT-CENTRICITY – A WINNING FORMULA
EXPERT VIEW
Justin Schroeder
PATIENT-CENTRICITY – A WINNING FORMULA
Justin Schroeder discusses patient-centricity, particularly how it relates to clinical trials in the modern global landscape of the pharmaceutical industry.
2014 TO 2018: AN UPDATE ON THE STATE OF WEARABLE INJECTORS
EXPERT VIEW
Paul Jansen
2014 TO 2018: AN UPDATE ON THE STATE OF WEARABLE INJECTORS
Looking back on the developments in large volume injectors since his article in ONdrugDelivery’s 2014 issue on wearable injectors, Paul Jansen reflects on the state of this technology space today, how it has progressed and the value it is likely to offer.
MOBILE DEVICES AND USE-RELATED RISK – TIME TO REINSTATE DETECTABILITY?
EXPERT VIEW
Richard Featherstone
MOBILE DEVICES AND USE-RELATED RISK – TIME TO REINSTATE DETECTABILITY?
Richard Featherstone makes the case for designing detectability into the user interfaces of wearable devices, enabling the user to be an active part of ensuring the device operates safely, as intended.
ORAL THIN FILMS: NOVEL TECHNOLOGY & ITS CHALLENGES
EXPERT VIEW
Dr Nidhi Prakash Sapkal
ORAL THIN FILMS: NOVEL TECHNOLOGY & ITS CHALLENGES
Presented from both the technology and formulation perspectives, Nidhi Prakash Sapkal and Anwar Siraj Daud discuss the challenges of industrialising oral thin films, a promising but difficult dosage form.
BEYOND MANUFACTURING: INDUSTRIALISATION OF DRUG DELIVERY IN THE REAL WORLD
EXPERT VIEW
Napoleon Monroe
BEYOND MANUFACTURING: INDUSTRIALISATION OF DRUG DELIVERY IN THE REAL WORLD
When discussing the industrialisation of drug delivery, it is natural to focus on the processes and management of manufacture. Napoleon Monroe provides a different perspective on the idea of drug delivery’s “Industrialisation” and what that might mean in the modern world of service industry.
THE BIGGEST MISTAKES COMPANIES MAKE COMMERCIALISING DRUG DELIVERY – AND WHAT TO DO ABOUT THEM
EXPERT VIEW
Beth Blackburn
THE BIGGEST MISTAKES COMPANIES MAKE COMMERCIALISING DRUG DELIVERY – AND WHAT TO DO ABOUT THEM
It is difficult to successfully scale-up a product to industrial production and launch, but it is much harder if design fundamentals are not adhered to. Beth Blackburn details the need for setting down requirements early in device development in order to avoid inadvertently undermining a product’s successful commercialisation.
A “KODAK” MOMENT FOR THE PHARMA INDUSTRY?
EXPERT VIEW
Dr Pari Datta
A “KODAK” MOMENT FOR THE PHARMA INDUSTRY?
Pari Datta and Nick Rollings discuss the concept of personalised medicine, with particular reference to oncology, and how it represents both an opportunity and a threat.
INTEGRATING CONNECTED HEALTH IN RESPIRATORY: THE MANUFACTURING CHALLENGE
EXPERT VIEW
David Belton
INTEGRATING CONNECTED HEALTH IN RESPIRATORY: THE MANUFACTURING CHALLENGE
David Belton highlights an often undiscussed aspect of the move towards connected drug delivery devices, the impact on manufacturing. Using inhalers as a reference point, he runs through several of the concerns and decisions that will need to be addressed for successful mass production of such devices.
THE NEED FOR A RELIABLE SUPPLY-CHAIN & HOW TO CREATE IT STRATEGICALLY
EXPERT VIEW
Antonio Teglia
THE NEED FOR A RELIABLE SUPPLY-CHAIN & HOW TO CREATE IT STRATEGICALLY
Antonio Teglia and Devon McCrossin discuss the increased importance of proper supply-chain management when it comes to mitigating the inherent production risks of today’s increasingly complex drug delivery devices.
GO WITH THE FLOW – SOLVING POWDER FLOW CHALLENGES BEFORE PRODUCTION
EXPERT VIEW
Jonathan Gaik
GO WITH THE FLOW – SOLVING POWDER FLOW CHALLENGES BEFORE PRODUCTION
Jonathan Gaik discusses the various problems in tablet compression that can be caused by not giving due care to powder flow in the development stage and how, by doing so, what would be serious problems at the industrial scale can be solved in advance.
PREVENTION NOT CURE: AVOIDING A EUROPEAN PRESCRIPTION OPIOID EPIDEMIC
EXPERT VIEW
Dr Damon C Smith
PREVENTION NOT CURE: AVOIDING A EUROPEAN PRESCRIPTION OPIOID EPIDEMIC
Damon Smith, Richard Dart and Christopher Hirst discuss the causes and possible solutions to the prescription opioid epidemic, as well as whether or not Europe is likely to face a similar fate.
ORAL FILMS – A MULTI-FACETED DRUG DELIVERY SYSTEM AND DOSAGE FORM
EXPERT VIEW
Rob Davidson
ORAL FILMS – A MULTI-FACETED DRUG DELIVERY SYSTEM AND DOSAGE FORM
Oral films are a relative newcomer to the drug delivery space, though one with considerable potential. Rob Davidson and Jessica Rousset give an overview of this dosage form, from formulation through manufacturing to future outlook.
THE SCIENCE OF SOLUBILITY AND THE SUCCESS OF AMORPHOUS SOLID DISPERSIONS
EXPERT VIEW
Rashmi Nair
THE SCIENCE OF SOLUBILITY AND THE SUCCESS OF AMORPHOUS SOLID DISPERSIONS
Rashmi Nair discusses the persistent challenge presented by poorly soluble drug formulations in oral drug delivery. Furthermore, she goes on to highlight the promise shown by amorphous solid dispersions, despite the difficulties they present.
NORMALISING CONNECTIVITY – COULD UNCONNECTED DEVICES BECOME THE EXCEPTION?
EXPERT VIEW
Charlotte Harvey
NORMALISING CONNECTIVITY – COULD UNCONNECTED DEVICES BECOME THE EXCEPTION?
Charlotte Harvey ponders the prospect of connectivity becoming the baseline for drug delivery device design – at what point will drug delivery devices without connectivity become the exception?
CONNECTED DRUG DELIVERY SECTOR OVERVIEW
EXPERT VIEW
Tom Oakley
CONNECTED DRUG DELIVERY SECTOR OVERVIEW
Tom Oakley gives an overview of the state of connected devices in the drug delivery world, touching on various approaches, benefits and challenges in the sector today.
THINK BEYOND THE DEVICE: THE MANY SIDES TO CONNECTIVITY
EXPERT VIEW
Alexander Dahmani
THINK BEYOND THE DEVICE: THE MANY SIDES TO CONNECTIVITY
Alexander Dahmani sheds light on some of the factors, beyond technical design and capabilities, involved in bringing a connected device to market.
THE SMART APPROACH TO HARNESSING DATA
EXPERT VIEW
Tom Lawrie-Fussey
THE SMART APPROACH TO HARNESSING DATA
As the drug delivery world moves to embrace big data, it is important to remember that unseen risks await the unwary. Tom Lawrie-Fussey explains further.
EXTRACTABLES AND LEACHABLES FOR INJECTION DEVICES
EXPERT VIEW
Mark Turner
EXTRACTABLES AND LEACHABLES FOR INJECTION DEVICES
Mark Turner explains the process involved in ensuring that pharmaceutical containers do not inadvertently transmit toxic substances, while maintaining the effectiveness of the active pharmaceutical ingredients (APIs).
THE FUTURE OF DRUG DELIVERY
EXPERT VIEW
Uri Baruch
THE FUTURE OF DRUG DELIVERY
Uri Baruch looks back on how far injectable drug delivery has come in the past thirty years and, with an eye on current trends and the range of innovations in the sector, particularly data and connectivity technology, looks forward to what the future may hold.
PHARMA PARTNERING CONSIDERATIONS FOR INJECTION DEVICE COMPONENTS
EXPERT VIEW
Adam Shain
PHARMA PARTNERING CONSIDERATIONS FOR INJECTION DEVICE COMPONENTS
In the modern world of injectable drugs, one of the major considerations for pharma is choosing partner companies for the development and manufacture of the injection device components. Adam Shain, discusses several of the considerations that go into ensuring that the best possible partner is selected.
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