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REDUCING THE COMPLEXITY OF LARGE-VOLUME SELF-INJECTION FOR PHARMA COMPANIES & PATIENTS
WEARABLES
Ian Thompson
Ypsomed
REDUCING THE COMPLEXITY OF LARGE-VOLUME SELF-INJECTION FOR PHARMA COMPANIES & PATIENTS
Ian Thompson updates us on YpsoDose, a new prefilled, large-volume patch injector platform, and how it is designed to simplify the approach to wearable injectors for both pharma companies and patients.
FROM VIAL TO WEARABLE INJECTOR
WEARABLES
Dr Kate Hudson-Farmer
FROM VIAL TO WEARABLE INJECTOR
While autoinjectors are often the delivery method of choice for patient self-administration, there are occasions when a vial and syringe format is required. To overcome the problems associated with this method, Medicom has developed a flexible, wearable patch pump which can accept a simple glass vial and provide a fully automated injection system. Hans Jensen and Kate Hudson-Farmer explain how it works.
GETTING TO KNOW SENSILE MEDICAL
INTERVIEW
Derek Brandt
GETTING TO KNOW SENSILE MEDICAL
Chief Executive Officer Derek Brandt and three of his colleagues – Christoph Lüdi, Head of Systems Engineering, Alex Perrier, Senior Technology Manager, and Marco Drüssel, Mechanical Engineering Manager – have all been a part of Sensile Medical for the past ten years, and here reflect on the company’s past and discuss the future.
ADVANCED APPROACHES FOR DELAYED-RELEASE FORMULATIONS
GI/ORAL
Dr Maria Montero Mirabet
Evonik
ADVANCED APPROACHES FOR DELAYED-RELEASE FORMULATIONS
Maria Montero Mirabet and Brigitte Skalsky, both of Evonik Health Care, review advances in delayed-release technology including advances in enteric-coating applications and the use of pulsatile technology to provide tailored lag times.
MEETING THE CHALLENGES OF PAEDIATRIC DOSING
GI/ORAL
Don Barbieri
MEETING THE CHALLENGES OF PAEDIATRIC DOSING
Although paediatric drugs are traditionally administered in a liquid formulation, recent studies suggest that orally disintegrating mini-tablets may be a more accurate, convenient and less messy dosage form. Don Barbieri explores this method and reviews two case studies looking at whether quality standards can be met and the importance of taste in paediatric formulations.
EVALUATING A NEW MICROSPHERE BASED CONTROLLED-RELEASE DELIVERY SYSTEM
EXPERT VIEW
Dr S Mohan Mohanraj
EVALUATING A NEW MICROSPHERE BASED CONTROLLED-RELEASE DELIVERY SYSTEM
S Mohan Mohanraj and Meir Kende discuss the development of a microsphere based delivery system for an orally administered anthrax vaccine.
THE PRESCRIPTION ABUSE EPIDEMIC: DESIGNING A SOLUTION
GI/ORAL
Aia Malik
THE PRESCRIPTION ABUSE EPIDEMIC: DESIGNING A SOLUTION
Aia Malik and Gemma Budd discuss the journey behind Lucideon’s proprietary iCRTdeter technology which provides tamper-proofing and enhanced safety of pharmaceuticals. It has been used to give abuse-deterrent features to formulations of opioids and highly potent compounds.
ORALLY DISINTEGRATING FILMS FOR THE DELIVERY OF BIOTHERAPEUTICS & NANO / MICROPARTICLE FORMULATIONS
GI/ORAL
Dr Carmen Popescu
Roquette
ORALLY DISINTEGRATING FILMS FOR THE DELIVERY OF BIOTHERAPEUTICS & NANO / MICROPARTICLE FORMULATIONS
Carmen Popescu summarises the benefits and applications of orally dissolving film dosage forms, with claims supported by two case studies, one demonstrating the suitability of ODFs for the delivery of micro and nanoparticles, the other showing how this property of ODFs exhibits promise as a next-generation immunisation system.
SINGLE-STEP FUNCTIONAL COATINGS FOR INCREASED EFFICIENCIES
GI/ORAL
Dr Nathan Dormer
SINGLE-STEP FUNCTIONAL COATINGS FOR INCREASED EFFICIENCIES
In this article about oral drug innovation, Cory Berkland and Nathan Dormer focus on how enterics and reverse enterics are applied into dosage forms, and discuss the future of this class of drug formulation technology.
OPPORTUNITIES & INNOVATIONS IN COLONIC DRUG DELIVERY
GI/ORAL
Dr Sejal R Ranmal
OPPORTUNITIES & INNOVATIONS IN COLONIC DRUG DELIVERY
Sejal R Ranmal, Vipul Yadav and Abdul W Basit describe recent insights into the physiology of the colon, advantages of targeting drug release to the colon and introduce Phloral®, Intract’s unique system for achieving drug release in the colon successfully and consistently.
TECHNOLOGIES & CLINICAL STUDIES FOR THE ORAL DELIVERY OF CALCITONIN
EXPERT VIEW
Dr Nozer Mehta
TECHNOLOGIES & CLINICAL STUDIES FOR THE ORAL DELIVERY OF CALCITONIN
Nozer Mehta, James P Gilligan and William Stern summarise the different technologies that have been in development for oral delivery of peptides through the gastro-intestinal mucosal surfaces via the transcellular or the paracellular pathways and describe the results of several long-term clinical studies on the oral delivery of salmon calcitonin.
ARNAUD GUILLET, BIOCORP
INTERVIEW
Arnaud Guillet
Biocorp
ARNAUD GUILLET, BIOCORP
Arnaud Guillet discusses Biocorp’s existing connected devices, value for pharmaceutical partners, accompanying software and data architecture and Biocorp's triple expertise in medical devices, electronics and software.
CONNECTED COMBINATION PRODUCTS: US ANALYSIS WITH POTENTIAL IMPLICATIONS WORLDWIDE
EXPERT VIEW
Napoleon Monroe
CONNECTED COMBINATION PRODUCTS: US ANALYSIS WITH POTENTIAL IMPLICATIONS WORLDWIDE
Napoleon Monroe provides an overview of the current status of connected combination products from the US perspective, with an emphasis on human factors, automated identity and regulation.
SMART DRUG DELIVERY: PRAGMATIC APPROACH REDUCES RISK, INCREASES INNOVATION & PATIENT ADHERENCE
CONNECTIVITY
Conor Mulcahy
Jabil Healthcare
SMART DRUG DELIVERY: PRAGMATIC APPROACH REDUCES RISK, INCREASES INNOVATION & PATIENT ADHERENCE
Getting patients to adhere to long-term therapy for asthma and chronic obstructive pulmonary disease remains a difficult issue to tackle. Conor Mulcahy discusses a smart inhaler which could help solve this problem.
IMPLANTS CONNECT PATIENTS FOR BETTER, FASTER, MORE PERSONALISED CARE
EXPERT VIEW
Will Rosellini
IMPLANTS CONNECT PATIENTS FOR BETTER, FASTER, MORE PERSONALISED CARE
Will Rosellini and Beth Rosellini describe the rapidly advancing area of local field potential recording of nervous system activity which has the ability to record patient data directly and has the potential to form highly advanced connected and closed-loop systems.
EMBEDDED CONNECTED METERED DOSE INHALERS MEETING REQUIREMENTS FOR MASS ADOPTION
CONNECTIVITY
Dr Benjamin Jung
H&T Presspart
EMBEDDED CONNECTED METERED DOSE INHALERS MEETING REQUIREMENTS FOR MASS ADOPTION
Benjamin Jung and Dana Shears describe the role connected devices can play in the treatment of asthma and COPD, discuss the requirements for mass adoption, and introduce H&T Presspart's inhaler, the eMDI, which has connectivity fully embedded.
PRODUCT SHOWCASE: FLEX DIGITAL HEALTH PLATFORM
CONNECTIVITY
Angela Wright
Flex
PRODUCT SHOWCASE: FLEX DIGITAL HEALTH PLATFORM
Angela Wright discusses how the Flex Digital Health group is building the world’s first medical regulated, HIPAA-compliant, open architecture platform of connected medical devices.
NOT JUST ANOTHER GADGET: INSIGHTS INTO DEVELOPING DIGITAL SOLUTIONS THAT WORK
CONNECTIVITY
SHL Medical
NOT JUST ANOTHER GADGET: INSIGHTS INTO DEVELOPING DIGITAL SOLUTIONS THAT WORK
Connected devices are increasingly widespread but their actual value and usefulness can sometimes get ignored. SHL Group believes that addressing four key questions is the way to avoid this happening in healthcare.
BEYOND CONNECTIVITY: ENABLE & FLEX ANNOUNCE THE ENABLE SMART DEVICE
CONNECTIVITY
Matthew Huddleston
Enable Injections
BEYOND CONNECTIVITY: ENABLE & FLEX ANNOUNCE THE ENABLE SMART DEVICE
Matthew J Huddleston and Angela Wright talk about integrating Bluetooth connectivity into Enable’s latest Smart On-Body Delivery Device, describing how the Flex/Enable partnership has also been expanded to encompass Flex’s Digital Health Platform.
THE POTENTIAL OF CONNECTED DEVICES FOR TACKLING ASTHMA
EXPERT VIEW
Garth Sutherland
THE POTENTIAL OF CONNECTED DEVICES FOR TACKLING ASTHMA
Garth Sutherland and Jon-Paul Sherlock explain how a strategic partnership between pharmaceutical companies and digital health companies can achieve improved outcomes through joint initiatives.
ADDRESSING EVOLVING HEALTHCARE NEEDS WITH DIGITAL HEALTH: CONNECTING DRUG DELIVERY
CONNECTIVITY
Dr Sundeep Kankanala
BD (Becton Dickinson & Company)
ADDRESSING EVOLVING HEALTHCARE NEEDS WITH DIGITAL HEALTH: CONNECTING DRUG DELIVERY
Sundeep Kankanala, Dave Icke and Chris Franzese explain how BD is moving towards providing solutions rather than products, particularly in the field of diabetes, discussing two frameworks created to improve the impact of the connected solutions.
SPECIALTY PHARMA: HOW PRESCRIBING TECHNOLOGY AFFECTS TREATMENT OUTCOMES
EXPERT VIEW
Dr Amy Seung
SPECIALTY PHARMA: HOW PRESCRIBING TECHNOLOGY AFFECTS TREATMENT OUTCOMES
New solutions are now available which streamline the Electronic Health Record workflows and automate difficult areas to aid in the problem of patient non-adherence, particularly in the specialty drug sector. Amy Seung explains how they can work.
HOW CONTEXT & CONNECTIVITY CONTRIBUTE TO A FULL PICTURE OF HEALTH
EXPERT VIEW
Erika Vázquez
HOW CONTEXT & CONNECTIVITY CONTRIBUTE TO A FULL PICTURE OF HEALTH
Erika Vazquez shows how recent technological advances make it possible to gather detailed contextual data about patients and gain true insights into whether their treatments are genuinely improving their quality of life.
THE PROMISE OF CONNECTED HEALTHCARE (AND WHY IT’S PROVING HARD TO GET THERE)
CONNECTIVITY
Kevin Deane
THE PROMISE OF CONNECTED HEALTHCARE (AND WHY IT’S PROVING HARD TO GET THERE)
Kevin Deane and Bill Welch show that clear trends are emerging, some helping to push connected healthcare forward and some that are slowing down progress, and describe the opportunities and challenges arising.

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Matt Kempton
Snr Project Engineer
Corning Incorporated

I am extremely impressed with the comprehensive presentation of information and problem/solution points detailed ... Kudos to you for an extremely well written article with succinct and robust scientific body of knowledge.


Donna Bibber
President
Micro Engineering Solutions

I picked up your latest copy at the Boston PODD event and read it with great interest. You’ve really come a long way and you put out an amazingly professional and value-packed magazine.


Dr Cristian Vilos

I‘m working on the development of microparticles for the release of veterinary antibiotics, and polymeric nanoparticles for siRNA and chemotherapeutic delivery. ONdrugDelivery has been a very usefull platform to connect the scientific research, and marketed drug development.


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Abby Lockwood
Consultant
Plan Strategic

ONdrugDelivery Magazine is a great resource that brings a lot of value to the work my team and I are doing in the area of drug delivery. The device-specific content as well as the broader discussions surrounding industry trends and issues are extremely informative and very well written.


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