ONdrugDelivery - ONdrugDelivery - drug delivery industry specialised b2b information

AIRLESS DRUG DELIVERY: WIDELY ACCEPTED, ACCESSIBLE AND AVAILABLE

Aptar Pharma's Stefan Hellbardt reflects on the role of Airless technology in the dermal drug delivery market and the benefits it offers.

WHY THE CONSISTENT CHALLENGES SURROUNDING MAPS ARE DISSOLVING FAST

Sebastian Braun discusses the current state of microneedle-based transdermal drug delivery, covering available microneedle delivery methods, the US FDA’s current stance on microneedle technologies and LTS’s microarray patch system and the possibilities it represents.

ENSURING FORMULATION PROTECTION AND PATIENT CARE WITH AIRLESS DISPENSERS

Audrey Chandra, Manuela Basso and Raphaële Audibert consider Nemera’s holistic approach to dermal drug delivery and its Sof’Bag^® technology.

MICRONEEDLES FOR INTRADERMAL DELIVERY OF CANCER VACCINES

Dr John Vasilakos

Kindeva Drug Delivery

MICRONEEDLES FOR INTRADERMAL DELIVERY OF CANCER VACCINES

John Vasilakos discusses the immuno-oncology market. He examines the role of cancer vaccines in supplementing other immuno-oncology therapies, as well as the value of delivering cancer vaccines intradermally.

AN ANGLED MICRONEEDLE PATCH FOR ENHANCED DRUG AND VACCINE DELIVERY

Dr Nicky Bertollo

AN ANGLED MICRONEEDLE PATCH FOR ENHANCED DRUG AND VACCINE DELIVERY

Nicky Bertollo, Ronan Byrne and Andrew Muddle introduce Pharma Latch – a user-centric angled microneedle patch technology. They discuss its key benefits, such as dramatically increased payload potential, precision, low cost and variable patch-wear times, and highlight how Pharma Latch has the potential to overcome many of the limitations of existing routes of administration for therapeutics and vaccines.

PRODUCT SHOWCASE: Logan Instruments’ Transdermal Testing Portfolio

Logan Instruments

PRODUCT SHOWCASE: Logan Instruments’ Transdermal Testing Portfolio

Logan Instruments, a provider of laboratory instrumentation to the global pharmaceutical and cosmetics industries, with a focus on physical, dissolution and transdermal testing systems, showcases its pioneering transdermal testing system offering.

MEDICSEN: NEEDLE-FREE SMARTPATCH FOR PAINLESS DRUG DELIVERY

Dr Eduardo Jorgensen

MEDICSEN: NEEDLE-FREE SMARTPATCH FOR PAINLESS DRUG DELIVERY

Eduardo W Jørgensen, Juan César de Mercado and José Carlos Montesinos describe the Smartpatch, a novel technology for subcutaneous delivery of drugs via a comfortable, pain-free patch using sonophoresis, based on Medicsen’s patented miniaturised ultrasound technology.

RS01X – BERRY GLOBAL HEALTHCARE’S SINGLE-DOSE DPI GOES DIGITAL WITH AMIKO’S RESPIRO

Berry Global Healthcare

RS01X – BERRY GLOBAL HEALTHCARE’S SINGLE-DOSE DPI GOES DIGITAL WITH AMIKO’S RESPIRO

Mauro Citterio, Director, Marco Franza and Martijn Grinovero discuss Berry and Amiko’s partnership to develop the RS01X connected single-dose dry powder inhaler, based on Berry’s commercialised RS01 inhaler and Amiko’s Respiro digital health platform.

CONNECTED DRUG DELIVERY: ACHIEVING OPTIMAL BENEFITS THROUGH SMART COLLABORATION

CONNECTED DRUG DELIVERY: ACHIEVING OPTIMAL BENEFITS THROUGH SMART COLLABORATION

George I’ons discusses the challenges developing connected devices presents to key market stakeholders when it comes to successful rollout and implementation. Additionally, he considers the perspectives of these market players, as well as the patients themselves, with respect to how connected drug delivery devices can help them to better achieve their desired outcomes.

MEDICAL DEVICE DESIGN STRATEGY FOR A CONNECTED FUTURE

Mr Michael Kiely

Jabil Healthcare

MEDICAL DEVICE DESIGN STRATEGY FOR A CONNECTED FUTURE

Michael Kiely, Laura Marsden, Peter Stringer, and David Boyle discuss the design challenges at the electromechanical interface and encourage manufacturers to adopt a standardised approach for connecting medical devices to the cloud.

THE CHANGING FACE OF CONNECTED HEALTH IN THE TIME OF COVID-19

Phillips-Medisize

THE CHANGING FACE OF CONNECTED HEALTH IN THE TIME OF COVID-19

Neil Williams and Angela R Eder both of Phillips-Medisize, discuss how the current pandemic is transforming the adoption of connected health.

MALLYA: ENLIGHTENING PAST, EXCITING PRESENT, PROMISING FUTURE

MALLYA: ENLIGHTENING PAST, EXCITING PRESENT, PROMISING FUTURE

Arnaud Guillet reviews the Mallya connected device platform, from the origins of the project to the current success in diabetes and deployment in other fields, and introduces the promising next-generation Mallya.

D-FLEX<sup>®</sup> ECOSYSTEM – FROM DATA TO VALUE

Dr Fred Metzmann

D-FLEX^® ECOSYSTEM – FROM DATA TO VALUE

Fred Metzmann and Frank Leipold discuss the benefits of connected medical devices in clinical trials and describe the advantages of Haselmeier's D-Flex^® Ecosystem for improving adherence and reducing the dropout rate in clinical trials.

AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING

Frédérique Bordes-Picard

AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING

Frédérique Bordes-Picard and Julien Lamps discuss the factors driving development in the area of capsule-based dry powder inhalers, and how the company’s Capsugel^® Zephyr™ portfolio offering is perfectly positioned to meet and exceed industry’s growing and evolving requirements.

DEVELOPMENT & PRODUCTION OF RESPIMAT<sup>®</sup> REUSABLE INHALER HOUSING MODULE

DEVELOPMENT & PRODUCTION OF RESPIMAT^® REUSABLE INHALER HOUSING MODULE

Josef Schmid, Markus Müller and Nina Zielonka discuss Gerresheimer’s recent work on developing the housing module for Boehringer Ingelheim’s new version of the Respimat inhaler.

ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS

INDUSTRIALISATION

Hosokawa Micron

ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS

Bert Dekens discusses Hosokawa Micron's offering for pharmaceutical powder mixing, including the Cyclomix high-shear mixer and the Nauta low-shear mixer, and how the company’s technology solutions take a broader approach to the full mixing process than simply providing a mixing machine.

INTRANASAL DELIVERY OF BIOLOGIC THERAPEUTICS AND VACCINES

Intertek Melbourn

INTRANASAL DELIVERY OF BIOLOGIC THERAPEUTICS AND VACCINES

David Ward looks at how the nasal route of drug administration offers the potential to improve the delivery of biologics, even for very complex molecules such as antibodies – and why strategic formulation is required to make this a reality.

SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES

SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES

João Pereira, Raquel Borda D’Água, Mark Copley and Anna Sipitanou, discuss the semi-automation of cascade impactor testing and the benefits it can bring in terms of quality of orally inhaled product test data, and reductions in cost and effort associated with routine, critical measurements.

ECONOMIC OPERATORS UNDER THE EU MDR: THE NEW REQUIREMENTS

ECONOMIC OPERATORS UNDER THE EU MDR: THE NEW REQUIREMENTS

Beth Crandall spells out the new requirements for Economic Operators under the EU Medical Device Regulation.

PULMO<emp>CRAFT</emp>™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY

Dr Richard Johnson

Upperton Pharma Solutions

PULMOCRAFT™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY

Richard Johnson discusses the techniques of jet milling and spray drying for the production of formulations for dry powder inhalers, and introduces Upperton Pharma’s PulmoCraft™ technology, which combines the advantages of both.

THE UNTOLD STORY OF NEMERA’S INHALATION FRANCHISE

Raphaële Audibert

THE UNTOLD STORY OF NEMERA’S INHALATION FRANCHISE

Raphaële Audibert and Niyati Sapatnekar tell the story of Nemera’s journey from contract manufacturer to end-to-end inhalation partner.

HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY

HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY

Howard Burnett explores how emotional intelligence can foster partnerships that have the potential to drive advances in understanding and improving patient outcomes, and presents the case for a single-source, turnkey approach to pulmonary solution development.

EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES

Dr Sion Coulman

Cardiff University

EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES

Sion Coulman, Siamac Parker, Prof James Birchall, Susana Ecenarro and Mahmoud Farag discuss new developments in low moisture content capsule technology for hygroscopic and very moisture-labile APIs.

MG2 AUTOMATION SOLUTIONS FOR INHALATION: R&D, TECHNOLOGICAL PARTNERSHIPS & SUCCESSFUL CASE HISTORIES

MG2 AUTOMATION SOLUTIONS FOR INHALATION: R&D, TECHNOLOGICAL PARTNERSHIPS & SUCCESSFUL CASE HISTORIES

Italian automation solutions provider MG2 describes its offering in the inhalation space, including unique benefits of collaboration and two example partnerships.

AEROGEN JOINS FORCES WITH 15 COMPANIES FOR COVID-19 INHALED THERAPIES

AEROGEN JOINS FORCES WITH 15 COMPANIES FOR COVID-19 INHALED THERAPIES

Aerogen has revealed details of a broad collaborative effort with more than 15 pharmaceutical companies for the development of covid-19 vaccines and treatments, including one with Synairgen for Solo/Ultra nebuliser-delivered SNG001 (inhaled interferon-beta-1a).

THE NEW EMERGING NEEDS DRIVING AUTOINJECTOR DEVELOPMENT

Dr Iain Simpson

Phillips-Medisize

THE NEW EMERGING NEEDS DRIVING AUTOINJECTOR DEVELOPMENT

Iain Simpson discusses the emerging needs to be considered when bringing new autoinjector drug-device combinations to market.

MEASURING & MANAGING MEDICATION ADHERENCE FROM CLINICAL TRIALS TO ROUTINE CARE: INJAY MEMS AS<sup>®</sup>

MEASURING & MANAGING MEDICATION ADHERENCE FROM CLINICAL TRIALS TO ROUTINE CARE: INJAY MEMS AS^®

Arnaud Guillet and Bernard Vrijens discuss the issue of medication non-adherence in both clinical trials and commercialised drug products, and how Biocorp’s Injay connected prefilled syringe solution combined with Aardex’s MEMS Adherence Software provides a solution.

THE “CUSTOMISABLE PLATFORM” PARADOX

INDUSTRIALISATION

THE “CUSTOMISABLE PLATFORM” PARADOX

Lyndon Wild and Gene Rhode Fuensalida Pantig present a systematic analysis of the customisable platform architecture found in the Molly^® autoinjector technology.

TRAINING DEVICES & PATIENT EDUCATION PLAY A CRUCIAL ROLE IN THE SELF-INJECTION DRUG DELIVERY MARKET

PREFILLED SYRINGES

TRAINING DEVICES & PATIENT EDUCATION PLAY A CRUCIAL ROLE IN THE SELF-INJECTION DRUG DELIVERY MARKET

Joe Reynolds discusses the role training devices and patient education play with regard to self-injection therapies.

GERRESHEIMER INCLUDES STEVANATO GROUP INTEGRATED TWIST-OFF CLOSURE SYSTEM FOR GX<sup>®</sup> RTF SYRINGES

PREFILLED SYRINGES

Mr Maximilian Vogl

GERRESHEIMER INCLUDES STEVANATO GROUP INTEGRATED TWIST-OFF CLOSURE SYSTEM FOR GX^® RTF SYRINGES

Maximilian Vogl reveals the latest user-friendly addition to its Gx RTF Luer lock syringes using Stevanto Group’s integrated twist-off closure technology.

UNISAFE<sup>®</sup> 2.25: SEAMLESSLY TRANSITIONING TO NEW-GENERATION BIOLOGICS

PREFILLED SYRINGES

UNISAFE^® 2.25: SEAMLESSLY TRANSITIONING TO NEW-GENERATION BIOLOGICS

George I’ons discusses the benefits of subcutaneously administering new drug formulations, and the factors that manufacturers need to consider when designing delivery devices.

VERIFYING THE CONTAINER CLOSURE INTEGRITY OF CUSTOM PRIMARY PACKAGING

PREFILLED SYRINGES

Oval Medical Technologies

VERIFYING THE CONTAINER CLOSURE INTEGRITY OF CUSTOM PRIMARY PACKAGING

Alex Vasiev, Connor Everett and Steven Hay explore the challenges of verifying the container closure integrity of custom primary packaging.

POLYMER SYRINGE CONSIDERATIONS FOR DRUG APPLICATIONS AND ADMINISTRATION

PREFILLED SYRINGES

West Pharmaceutical Services

POLYMER SYRINGE CONSIDERATIONS FOR DRUG APPLICATIONS AND ADMINISTRATION

Tibor Hlobik compares cyclo-olefin polymers and copolymers with glass as the material of choice for prefilled syringes, in particular discussing the benefits of polymers when it comes to biologic drug products and prefilled syringes for use in autoinjectors.

OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

PREFILLED SYRINGES

Mitsubishi Gas Chemical

OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

Shota Arakawa and Tomohiro Suzuki discuss MGC’s OXYCAPT™ vial and syringe primary containers, including the OXYCAPT™ material and product offering, as well as where MGC sees OXYCAPT™ fitting into the modern pharmaceutical market.

VERIFICATION OF INJECTABLES IN TRANSPORT AND STORAGE

PREFILLED SYRINGES

Medical Engineering Technologies

VERIFICATION OF INJECTABLES IN TRANSPORT AND STORAGE

Mark Turner discusses the regulations and requirements around testing combination products for their stability in storage over their shelf-life and during transport.

ENHANCING PROTEIN PRESERVATION DURING BIOLOGICAL DRUG PREPARATION AND DELIVERY

Adrien Bouillet

ENHANCING PROTEIN PRESERVATION DURING BIOLOGICAL DRUG PREPARATION AND DELIVERY

Adrien Bouillet, Loïc Girois and Marianne Weidenhaupt, discuss the results of work carried out in joint efforts by EVEON and LMGP in the field of protein adsorption and aggregation, and how the results of this work have led to improvements in the design of EVEON’s proprietary micropump.

THE CHANGING FACE OF AUTOINJECTOR TECHNOLOGY

Bespak by Recipharm

THE CHANGING FACE OF AUTOINJECTOR TECHNOLOGY

Reenal Gandhi discusses the advantages offered by liquefied gas as a power source for autoinjectors compared with conventional spring-based systems, as well as covering the benefits of using a platform model for drug delivery device development.

THE IMPORTANCE OF A GREAT DEVELOPMENT EXPERIENCE TO ACHIEVE A GREAT MEDICAL DEVICE

PREFILLED SYRINGES

William Fortina

THE IMPORTANCE OF A GREAT DEVELOPMENT EXPERIENCE TO ACHIEVE A GREAT MEDICAL DEVICE

William Fortina considers the importance of the medical device development experience in the healthcare context and discusses the factors that make for a superior development process.

HOW LONG CAN YOU HOLD THE DEVICE AGAINST THE SKIN? INSIGHTS FROM AN EMPIRICAL STUDY USING HAND-HELD AUTOINJECTORS

Dr Andreas Schneider

HOW LONG CAN YOU HOLD THE DEVICE AGAINST THE SKIN? INSIGHTS FROM AN EMPIRICAL STUDY USING HAND-HELD AUTOINJECTORS

Andreas Schneider summarises recent empirical work investigating the ability of users of hand-held devices to complete longer injection times effectively. The study provides insights into the effects of injection duration on the force exerted by the user to hold the device against the injection site.

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