ONdrugDelivery - ONdrugDelivery - drug delivery industry specialised b2b information

YPSODOSE – SIMPLIFYING LARGE-VOLUME PATCH INJECTIONS

Ypsomed's Ian Thompson provides the latest insights into the YpsoDose prefilled and pre-assembled patch injector as it moves into the industrialisation phase for clinical trials.

THE PATH TO COMMERCIALISATION FOR WEARABLE DRUG DELIVERY DEVICES

Atul Patel looks at the evolution of the wearable drug delivery market, including the route to commercialisation and the challenges faced.

EXTENDING CONTAINER CLOSURE INTEGRITY TO WEARABLE INJECTORS

Shaun Devitt looks at how the principles and methods of container closure integrity might be adapted for wearable injectors.

DESIGNING DRUG DELIVERY DEVICES THROUGH COLLABORATIVE USABILITY TESTING

DESIGNING DRUG DELIVERY DEVICES THROUGH COLLABORATIVE USABILITY TESTING

Alice Bogrash examines how the company uses human factors studies to design drug delivery devices that respond to user needs, while providing a competitive advantage for pharmaceutical companies looking to introduce innovative combination products to the market.

MEETING EMERGING STAKEHOLDER NEEDS WITH THE SUBCUJECT WEARABLE BOLUS INJECTOR

Phillips-Medisize

MEETING EMERGING STAKEHOLDER NEEDS WITH THE SUBCUJECT WEARABLE BOLUS INJECTOR

Tony Bedford looks at the emerging market for on-body injectors coupled with stakeholder needs and introduces the Subcuject wearable bolus injector, which is designed to accommodate these requirements.

TACKLING HIGH-VOLUME ADMINISTRATION CHALLENGES WITH A SMART, SUSTAINABLE ON-BODY INJECTOR PLATFORM

Séverine Duband

TACKLING HIGH-VOLUME ADMINISTRATION CHALLENGES WITH A SMART, SUSTAINABLE ON-BODY INJECTOR PLATFORM

Séverine Duband introduces Symbioze, Nemera’s novel on-body injector platform device, comprising a reusable main unit and disposable prefilled drug container, and offering a balance between the need to deliver advanced formulations at high volumes and the desire for patient-centric ease-of-use that enables patients to self-administer their therapies at home.

HIGH PRECISION IN PLASTICS IMPROVES THE QUALITY OF LIFE OF DIABETES PATIENTS

Weidmann Medical Technology

HIGH PRECISION IN PLASTICS IMPROVES THE QUALITY OF LIFE OF DIABETES PATIENTS

Steffen Reuter discusses the importance of high precision when manufacturing injection moulded components for wearable insulin delivery devices, with particular reference to three such parts from a recent project as a case study for Weidmann Medical Technology’s approach.

USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN

USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN

Enrico Denna looks at the advantages of a simulation and modelling approach over prototyping for the design of medical products.

COMPLEXITY OF PATCH PUMP ASSEMBLY AND CONSIDERATIONS FOR MASTERING IT

COMPLEXITY OF PATCH PUMP ASSEMBLY AND CONSIDERATIONS FOR MASTERING IT

Roger Nordy discusses the complexities of patch pump assembly and explains how ATS has been mastering the intricacies of the automation process to take on the growing industry demand.

VECTRA<sup>®</sup> MT<sup>®</sup> LCP BRINGS THE ADVANTAGES OF LIQUID CRYSTAL POLYMERS TO WEARABLE INJECTORS

VECTRA^® MT^® LCP BRINGS THE ADVANTAGES OF LIQUID CRYSTAL POLYMERS TO WEARABLE INJECTORS

Wim Vos, Dave Pellegrino and Rob Haley discuss the myriad benefits of Vectra^® MT^® LCP, Celanese’s medical-grade liquid crystal polymer, for wearable injection devices, including improved patient comfort, greater design flexibility and reduced processing costs.

REPOSITIONING FROM IV TO VIAL-BASED SC FOR LARGE-VOLUME BIOLOGICS

REPOSITIONING FROM IV TO VIAL-BASED SC FOR LARGE-VOLUME BIOLOGICS

Tom Mayer discusses the growing trend of moving away from intravenous drugs administered in clinical and hospital settings to at-home, self-administered vial-based subcutaneous delivery for cost savings, better lifecycle management and improved care.

OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES

OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES

Tim Resker looks at new technologies for powering on battery-operated drug delivery devices while considering battery drain, ingress protection and user-friendliness.

DRUG DELIVERY: WHAT DO PATIENTS AND PROVIDERS WANT?

Matthew Huddleston

Enable Injections

DRUG DELIVERY: WHAT DO PATIENTS AND PROVIDERS WANT?

Matthew Huddleston and Jennifer Estep discuss current drug delivery options and the value of convenient care.

CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS

Marcus Jarman-Smith

CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS

Marcus Jarman-Smith, Adam Salmen, John Devine, Ernst Hupkes and Dennis Freie discuss the value of PEEK, a high-performance polymer, in drug delivery device design, using two concept devices – an on-body patch pump and vaporiser inhaler.

The Secrets of Solubility Enhancement Success with EUDRAGIT<sup>®</sup> Carriers

Dr Jessica Mueller-Albers

The Secrets of Solubility Enhancement Success with EUDRAGIT^® Carriers

ONLINE ONLY - Jessica Mueller-Albers discusses how Evonik’s EUDRAGIT^® functional polymers can enhance drug solubility and permeability, with a focus on carriers, screening tools and manufacturing processes.

ARE VIRTUAL EVENTS A SUITABLE REPLACEMENT FOR FACE-TO-FACE EQUIVALENTS POST-PANDEMIC?

Mr Denis Marteau

ARE VIRTUAL EVENTS A SUITABLE REPLACEMENT FOR FACE-TO-FACE EQUIVALENTS POST-PANDEMIC?

Denis Marteau looks at the future of virtual industry events and conferences in a post-pandemic future.

DEVELOPING A FULLY AUTOMATED MODULAR MACHINE PLATFORM FOR AUTOINJECTOR TESTING

INDUSTRIALISATION

DEVELOPING A FULLY AUTOMATED MODULAR MACHINE PLATFORM FOR AUTOINJECTOR TESTING

Lucy Chung and Gilbert Fluetsch discuss the benefits of a modular automated test platform.

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Dr Antonio Costa

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Antonio Costa discusses the use of lipid nanoparticles in the modern drug delivery industry and introduces the DIANT system for the continuous processing of nanoparticles with integrated process analytical technology, which can provide the quality required for these injectable, complex formulations.

THE FUTURE OF CONTAINER-LEVEL TRACEABILITY FOR PREFILLABLE SYRINGES

INDUSTRIALISATION

BD (Becton Dickinson & Company)

THE FUTURE OF CONTAINER-LEVEL TRACEABILITY FOR PREFILLABLE SYRINGES

Sam Eubanks and Hervé Soukiassian discuss the BD traceability solution. This concept under development aims to deliver traceability at the unique container level from manufacture to the point of care.

INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING

INDUSTRIALISATION

Napoleon Monroe

New Directions Technology Consulting

INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING

Napoleon Monroe considers the impact of the changing technological landscape on how industrialisation in the healthcare industry is evolving, with reference to the idea of “patients as consumers” and how the relationship between consumers, information and industry has evolved in other sectors, such as tech and retail – and how big players in those sectors are looking to move into and disrupt healthcare.

UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

INDUSTRIALISATION

Hiroki Hasegawa

Mitsubishi Gas Chemical

UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

Hiroki Hasegawa and Tomohiro Suzuki discuss the advantages of OXYCAPT™ multilayer plastic vial and syringe, which combine the benefits of cyclo-olefin polymer with excellent oxygen and UV barrier properties. In particular, the authors focus on recent studies that highlight OXYCAPT’s very low levels of extractables.

THE FOURTH INDUSTRIAL REVOLUTION – ROBOTICS AND THE LABORATORY

INDUSTRIALISATION

Prof Marc Brown

THE FOURTH INDUSTRIAL REVOLUTION – ROBOTICS AND THE LABORATORY

Marc Brown and Jon Lenn look at MedPharm’s implementation of automated robotic systems in enhancing workflow and the company’s plans for the future implementation of robotics in formulation development.

AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE

AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE

Richard Gray and Julia Rashba-Step discuss the benefits of automated lipid nanoparticle production.

OVERCOMING DEVELOPMENT OBSTACLES TO THE DELIVERY OF EFFECTIVE OCULAR THERAPY

OVERCOMING DEVELOPMENT OBSTACLES TO THE DELIVERY OF EFFECTIVE OCULAR THERAPY

Robert Lee discusses the growth of the ocular drug delivery market, the challenges formulators face in developing novel ocular technologies, and the role contract development and manufacturing organisations have to play in this growing market segment.

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Mr Richard Joye

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Richard Joye and Tim Morch discuss the advantages of using dissolvable microneedles for the delivery of vaccines, particularly in regards to storage and transport, and introduce SeriTech’s fast-detaching dissolvable microneedle technology.

REMOVING CLINICAL TRIAL BIAS WITH OVER-ENCAPSULATION

Frédérique Bordes-Picard

REMOVING CLINICAL TRIAL BIAS WITH OVER-ENCAPSULATION

Frédérique Bordes-Picard, Julien Lamps and Stephen Rode discuss the considerations to take into account when using over-encapsulation to blind clinical trials, including the advantages of hydroxypropyl methylcellulose over gelatin as a material.

GASTRIC FLOATING MICROCAPSULES FOR THE MANAGEMENT OF PARKINSON’S DISEASE

Dr Sashi Kesavapany

GASTRIC FLOATING MICROCAPSULES FOR THE MANAGEMENT OF PARKINSON’S DISEASE

Kaarunya Sampathkumar, Joachim Loo and Sashi Kesavapany discuss current treatments for Parkinson’s disease and introduce an extended-releasing technology for polypharmacy oral formulations.

NANOPARTICLE ENGINEERING AND 3DP DELIVERY FOR GAME-CHANGING ORAL THERAPEUTICS

NANOPARTICLE ENGINEERING AND 3DP DELIVERY FOR GAME-CHANGING ORAL THERAPEUTICS

Niklas Sandler and Thomas West consider the technological advances in nanoparticle engineering that can improve the bioavailability and delivery of oral therapeutics.

ADDRESSING ONGOING AND NEW BIOAVAILABILITY CHALLENGES

Dr Stephanie Emory

ADDRESSING ONGOING AND NEW BIOAVAILABILITY CHALLENGES

Stephanie Emory explores the pros and cons of various technologies for enhancing solubility and bioavailability for oral drug formulations. Further, Dr Emory draws on her experience as a reviewer at the US FDA to discuss how developers can view the FDA as a partner to aid success when leveraging innovative approaches.

PRODUCT SHOWCASE: Evonik’s newly launched EUDRACAP™ functional, ready-to-fill capsules

PRODUCT SHOWCASE: Evonik’s newly launched EUDRACAP™ functional, ready-to-fill capsules

Evonik introduces EUDRACAP™, its newly launched platform of functional ready-to-fill HPMC capsules, which helps optimise release profile, protects sensitive active ingredients, and speeds time to market.

ANALYTICAL TECHNIQUES FOR THE FORMULATION OF GASTRORETENTIVE TABLETS

ANALYTICAL TECHNIQUES FOR THE FORMULATION OF GASTRORETENTIVE TABLETS

Jamie Clayton, Phil Bone and Kyu Mok Hwang discuss the value of analyses such as mercury porosimetry and powder rheology in characterising excipients for gastroretentive tablet formulation, and go on to detail a case study investigating polymer excipients for a novel bilayer floating tablet.

PATENTS ARE IMPORTANT FOR SMART HEALTHCARE PRODUCTS

Napoleon Monroe

New Directions Technology Consulting

PATENTS ARE IMPORTANT FOR SMART HEALTHCARE PRODUCTS

Napoleon Monroe discusses the value of internet-connected smart devices in present-day healthcare, and introduces the mMed patent portfolio, of which Mr Monroe is the sole inventor, and which contains five US patents for key connected health technologies.

THE POWER OF ONBOARDING: BUILDING PERSUASIVE USER EXPERIENCES FOR COMPANION APPS

THE POWER OF ONBOARDING: BUILDING PERSUASIVE USER EXPERIENCES FOR COMPANION APPS

Ben Cox discusses the value of onboarding in drug delivery device companion apps, and how it is a key component of converting a one-time user to a repeat user, unlocking the true value of companion apps as a tool for combating poor adherence to medications and gathering high-quality data.

IMPROVING PATIENT OUTCOMES WITH ADVANCED DIGITAL BIOMARKERS

Sagentia Innovation

IMPROVING PATIENT OUTCOMES WITH ADVANCED DIGITAL BIOMARKERS

Matthew Sarkar and Imantha Samaranayake consider the contribution digital biomarker devices make towards healthcare and the challenges faced by the evolution of such devices.

MEANING-CENTRED PRODUCT DEVELOPMENT: THE KEY TO SUCCESSFUL CONNECTED DISEASE MANAGEMENT

Christina Philpott

MEANING-CENTRED PRODUCT DEVELOPMENT: THE KEY TO SUCCESSFUL CONNECTED DISEASE MANAGEMENT

Christina Philpott, Miles Hawley and Natasha French, discuss the future of connected disease management and the potential benefits for asthma treatment.

CYBERSECURITY AND CONNECTED DRUG DELIVERY – AN INTEGRATED RISK-BASED APPROACH

John Whitehouse

CYBERSECURITY AND CONNECTED DRUG DELIVERY – AN INTEGRATED RISK-BASED APPROACH

John Whitehouse, Rob Veasey and Shane Day, discuss the value of integrating cybersecurity into a holistic, multidisciplinary approach to risk management for connected medical devices.

SPECIALTY LCP COMPOUNDS FOR ELECTRONICS INTEGRATION IN CONNECTED MEDICAL DEVICES

SPECIALTY LCP COMPOUNDS FOR ELECTRONICS INTEGRATION IN CONNECTED MEDICAL DEVICES

Young Kim, Don DeMello and Philip Wilson, discuss the benefits of recent advances in liquid crystal polymer for connected medical devices.

PRACTICAL INSIGHTS INTO LACTOSE-BASED DPI FORMULATIONS, WITH & WITHOUT MAGNESIUM STEARATE

PRACTICAL INSIGHTS INTO LACTOSE-BASED DPI FORMULATIONS, WITH & WITHOUT MAGNESIUM STEARATE

Partners DFE Pharma, Hosokawa Micron and Harro Höfliger describe their unique multidisciplinary study into lactose-based DPI formulations including magnesium stearate, whose findings will give generic players a head-start in the development process so that they can tap into this rapidly growing market. The three companies announce that they will be presenting the key insights from their research to interested parties during a joint webinar on the June 30th, 2020.

ENSURING FUNCTIONAL PERFORMANCE AND REGULATORY COMPLIANCE OF ELASTOMER STOPPERS FOR MULTIPIERCING SITUATIONS

ENSURING FUNCTIONAL PERFORMANCE AND REGULATORY COMPLIANCE OF ELASTOMER STOPPERS FOR MULTIPIERCING SITUATIONS

Bruno Morchain, Sébastien Cordier and Estelle Verger discuss a series of experiments conducted on Aptar Pharma’s PremiumCoat^® vial stoppers to demonstrate their compliance with EU and US Pharmacopeia standards and their excellent performance in multipiercing situations

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