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THE FUTURE OF CONNECTED ASTHMA AND COPD CARE: A STEPWISE DEVELOPMENT

Dr Benjamin Jung

THE FUTURE OF CONNECTED ASTHMA AND COPD CARE: A STEPWISE DEVELOPMENT

Benjamin Jung outlines possible scenarios for the likely steps in the development and adoption of connected devices in the field of asthma and COPD care.

Biocorp’s OneJet<sup>®</sup> connected autoinjector

Biocorp’s OneJet^® connected autoinjector

Onejet is the first motor-driven, disposable and connected autoinjector. It's compatible with standard primary containers and is customisable allowing it to easily deliver high viscosity products. Injection data (time, doses and date) are transferred to a mobile app via Bluetooth, allowing monitoring of key treatment information.

9th Global Drug Delivery Summit Highlights

9th Global Drug Delivery Summit Highlights

FINAL ASSEMBLY, LABELLING & PACKAGING

PREFILLED SYRINGES

FINAL ASSEMBLY, LABELLING & PACKAGING

For the development of combination products, pharma and biotech companies have the option to establish an assembly and packaging infrastructure internally or to outsource to a contract manufacturing organisation. One such organisation, SHL, explains what the benefits are of using a manufacturing partner and outlines what it can offer in terms of an integrated process.

PRODUCT REVIEW – SAFE’N’SOUND<sup>®</sup> & SAFELIA<sup>®</sup>

PREFILLED SYRINGES

Séverine Duband

PRODUCT REVIEW – SAFE’N’SOUND^® & SAFELIA^®

Séverine Duband provides a rundown of the features of Nemera’s injectable device offering, the Safe’n’Sound^® single-use safety device and the Safelia^® two-step autoinjector.

CREATING PREFILLABLE SYRINGES FOR THE BIOLOGICS MARKET

PREFILLED SYRINGES

Fabian Stöcker

CREATING PREFILLABLE SYRINGES FOR THE BIOLOGICS MARKET

Nicolas Eon and Fabian Stöcker discuss syriQ BioPure^®, a high-end prefillable syringe for biologics, which integrates seamlessly with autoinjectors and an innovative filling platform.

INSERT. WEAR. INJECT. DISPOSABLE UNITS FOR WEARABLE DRUG DELIVERY DEVICES

INSERT. WEAR. INJECT. DISPOSABLE UNITS FOR WEARABLE DRUG DELIVERY DEVICES

Mobile drug delivery pumps can significantly improve patients’ quality of life, however they require highly advanced disposable components to ensure that patients receive the exact dose required. Claudia Fink reviews how the components are produced and which secondary processing techniques are required and Raumedic's partnership with Sensile Medical.

AUTOINJECTOR TRAINER INNOVATIONS TO ENHANCE THE PATIENT EXPERIENCE

PREFILLED SYRINGES

AUTOINJECTOR TRAINER INNOVATIONS TO ENHANCE THE PATIENT EXPERIENCE

Joe Reynolds looks at the benefits offered by Noble's innovative agitator needle simulation tip – which can be incorporated into several types of autoinjector trainers – and reviews the development process.

/H&B/’S FOUR-STEP-TECHNOLOGY

PREFILLED SYRINGES

/H&B/’S FOUR-STEP-TECHNOLOGY

Tobias Morlok outlines how the company’s Four-Step-Technology approach ensures that devices are totally safe to use by protecting against inappropriate use in several ways and at four key stages.

MAKING SELF-ADMINISTRATION POSSIBLE FOR ALL PATIENTS

PREFILLED SYRINGES

West Pharmaceutical Services

MAKING SELF-ADMINISTRATION POSSIBLE FOR ALL PATIENTS

At West, extensive human factors studies were carried out to help create the SelfDose™ patient-controlled injector, designed for patients who have dexterity problems. Carl Dabruzzi, Director, Product Management, Self-Injections Systems explains more.

EXTRACTABLES AND LEACHABLES FOR INJECTION DEVICES

EXTRACTABLES AND LEACHABLES FOR INJECTION DEVICES

Mark Turner explains the process involved in ensuring that pharmaceutical containers do not inadvertently transmit toxic substances, while maintaining the effectiveness of the active pharmaceutical ingredients (APIs).

PHARMA PARTNERING CONSIDERATIONS FOR INJECTION DEVICE COMPONENTS

PHARMA PARTNERING CONSIDERATIONS FOR INJECTION DEVICE COMPONENTS

In the modern world of injectable drugs, one of the major considerations for pharma is choosing partner companies for the development and manufacture of the injection device components. Adam Shain, discusses several of the considerations that go into ensuring that the best possible partner is selected.

THE FUTURE OF DRUG DELIVERY

THE FUTURE OF DRUG DELIVERY

Uri Baruch looks back on how far injectable drug delivery has come in the past thirty years and, with an eye on current trends and the range of innovations in the sector, particularly data and connectivity technology, looks forward to what the future may hold.

CONNECTED, NEEDLE-FREE DRUG DELIVERY

Portal Instruments

CONNECTED, NEEDLE-FREE DRUG DELIVERY

The healthcare industry is seeing an ever growing trend towards patients self-administering their therapies at home. Barbara Taylor discusses this trend and how Portal is making a bold step towards this goal with its novel needle-free injection device.

THE SECRET TO A SINGLE AUTOINJECTOR DESIGN FOR MULTIPLE MEDICATIONS

PREFILLED SYRINGES

David Philbrick

Paragon Medical

THE SECRET TO A SINGLE AUTOINJECTOR DESIGN FOR MULTIPLE MEDICATIONS

The autoinjector market is booming and is predicted to continue doing so for some time to come. In order to capitalise on this, pharma companies are looking to use their autoinjectors for multiple medications. David Philbrick presents the case for bringing on metal component manufacturers in the initial design phase to make the most out of the crucial expertise they can offer.

ENABLE INJECTIONS AND FLEX SET AMBITIOUS PLANS FOR LARGE VOLUME DRUG DELIVERY

Enable Injections

ENABLE INJECTIONS AND FLEX SET AMBITIOUS PLANS FOR LARGE VOLUME DRUG DELIVERY

The delivery of high volumes of biologics outside of the clinical setting remains a key challenge in the industry. Here, John Love, Mark Lee and Amy Boyle discuss how the enFuse™ on-body injector, developed by Enable in partnership with Flex, may be the answer.

A POSITIVE SPIN ON DPI FORMULATION

A POSITIVE SPIN ON DPI FORMULATION

Bert Dekens outlines some of the considerations that go into developing and processing dry powder inhaler formulations, and discusses the merits of conical high-shear mixers.

POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY

Dr Karlheinz Seyfang

POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY

Karlheinz Seyfang discusses the need for filling verification in pre-metered DPI blister filling lines, going on to detail the role X-ray analysis could play in an automated verification process.

COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING

Proveris Scientific

COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING

Heli Chauhan outlines the major challenges encountered in testing pressurised metered dose inhalers, and how Proveris’ portfolio of instruments can be an invaluable addition to the testing workflow.

DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM

DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM

Badre Hammond, Gerallt Williams and Herve Pacaud discuss the growing trend of drug repurposing.

INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION

INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION

Pascale Farjas, Alain Regard and Guillaume Grevin, discuss what is required of a modern nasal spray pump and how introducing the human factor showed a significant impact on the variability of delivered volume.

REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS

REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS

Craig Baker discusses the prevalence of improper use and how addressing this issue via training devices is of benefit to manufacturers, healthcare providers and patients.

THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES

THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES

Mary Hutchens gives an overview of some of the changes wrought by last year’s introduction of the new EU Medical Device Regulation, with a specific view to its effect on inhalation devices and inhaled medical products.

CHOOSING THE RIGHT DOSATOR FOR DPI DOSING

CHOOSING THE RIGHT DOSATOR FOR DPI DOSING

Jamie Clayton, Rajeev Dattani and Dave Seaward discuss the operation of dosators for reliable and accurate filling of DPI capsules and blisters.

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