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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
CONTRIBUTE
MEDIA PACK
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PULMONARY
PULMONARY
Noble
COMPANY SHOWCASE: NOBLE
Noble®, the leader in onboarding and device training, is a full-service, patient-centred product development and manufacturing company.
PULMONARY
Bill Welch
Phillips Medisize
SYSTEMS ENGINEERING FOR COMPLEX PORTABLE DRUG DELIVERY DEVICE DEVELOPMENT
Bill Welch explains how a systems-engineering approach provides an efficient method of developing smaller, smarter and more complex inhaler devices.
PULMONARY
Adam Smith
Copley Scientific
COMPANY SHOWCASE: NOVI
In December 2015 the inhaler automation specialists Novi Systems launched their latest product, a ten-way shake and fire system for pMDIs called DecaVertus. Novi continues to innovate, bringing efficiency, precision and repeatability to inhalation labs around the world.
PULMONARY
Vaishali Kamat
Cambridge Consultants
IT’S JUST AN APP, ISN’T IT?
Vaishali Kamat and Jaquie Finn, outline some key questions that pharma companies should ask before embarking on the development of a connected health solution, and provide insights that could help companies make the most from their investment.
PULMONARY
Dr Gabriela Dujovny
Qualicaps
OPTIMAL SOLUTION FOR DIFFERENT INSPIRATIONAL RATES
There is a wide range of devices available to deliver inhalation therapies, but there is increasing interest in the use of dry powder inhalers due to improved engineering and powder formulations. Gabriela Dujovny looks at the advantages and disadvantages of the DPIs currently available.
PULMONARY
Dr David L Hava
ADVANCES IN PULMONARY DELIVERY OF INHALED ANTI-INFECTIVES
With the growing problems caused by antimicrobial resistance, there is increasing interest in the use of improved strategies for drug delivery. David L. Hava explores the benefits of nebulised inhaled antibiotics delivered via high throughput nebulisers for aqueous formulations or dry powder inhalations for cystic fibrosis patients.
PULMONARY
Inga Meyer
Nemera
INHALIA
®
: A NEW pMDI METERING VALVE PLATFORM THAT PATIENTS CAN COUNT ON
Inga Meyer introduces the company’s new pressurised metered-dose inhaler (pMDI) valve platform, Inhalia, and uses device testing study data to demonstrate some of the significant advances, advantages and benefits the platform brings.
PULMONARY
Paul Sullivan
Noble
PATIENT PREFERENCE IN RESPIRATORY DEVICE TRAINING & EDUCATIONAL TOOLS
Paul Sullivan and Craig Baker provide data from recent patient studies to emphasise the importance of training devices in improving adherence to, and compliance with, inhaled therapeutics.
EXPERT VIEW
Mark Tunkel
WHY SUCCESS IN DRUG DELIVERY IS NOT JUST ABOUT THE DEVICE
Mark Tunkel explains how companies developing and marketing inhalable pharmaceuticals can explore other strategies to improve patient outcomes over and above what the drug and device can achieve.
PULMONARY
Dr David Lewis
REVIEWING CURRENT THINKING ON THE
IN VIVO
BEHAVIOUR OF PARTICLES IN THE EXTRA-FINE REGION
David Lewis reports the latest research on the changing view of the behaviour of particles in the extra-fine region and their potential for enhancing inhaled drug therapies.
PULMONARY
Richard Turner
H&T Presspart
IMPROVING DRUG STABILITY & DRUG DELIVERY BY MODIFICATION OF MDI CANISTER SURFACES
Richard Turner explains how, in recent years, a number of surface coatings have been developed that can be applied to MDIs canisters and valve components, to protect the contents from deposition and degradation.
PULMONARY
Adam Smith
Copley Scientific
A NEW, ADVANCED HIGH-THROUGHPUT SYSTEM FOR AUTOMATED INHALER TESTING
Adam Smith introduces DecaVertus, describing its single inhaler predecessor the Vertus, and how the DecaVertus design evolved using the Vertus technology.
PULMONARY
Dr Paul Kippax
Malvern Panalytical
INVESTIGATING THE DE-AGGLOMERATION PROFILES OF DPI FORMULATIONS
Paul Kippax from Malvern Instruments, Srinivas Ravindra Babu Behara, David Morton, Ian Larson and Peter Stewart from Monash University describe the use of laser diffraction to analyse dry powder behaviour.
PULMONARY
Dr Timothy Noakes
MDI PROPELLANTS – IS THE POPULARITY OF HFA 227EA SET TO GROW?
Tim Noakes predicts a rise in demand for HFA 227ea – a less common MDI propellant than the better-known HFA 134a.
PULMONARY
Mark Copley
Copley Scientific
IMPROVING THE REALISM AND RELEVANCE OF MOUTH-THROAT MODELS FOR INHALED PRODUCT TESTING
Mark Copley provides some background on mouth-throat models for OIP testing.
PULMONARY
David Harris
Team Consulting
THE ADVANTAGES OF DESIGNING HIGH-RESISTANCE SWIRL CHAMBERS
David Harris taps into a powerful combination of detailed anatomical and functional understanding of the human respiratory system, pulmonary drug delivery technology and formulation expertise.
PULMONARY
Dr Anna Fureby
PULMONARY DELIVERY OF ANTIMICROBIAL PEPTIDES
Anna Fureby, Ulla Elofsson and Per Gerde discuss the serious problem of antibiotic resistance and the potential role of antimicrobial peptides in the treatment of resistant bacterial strains.
PULMONARY
EXPERTISE IN DEVELOPMENT, MANUFACTURING & COMMERCIALISATION
3M Drug Delivery Systems reports on how it has achieved significant successes thanks to its deep expertise in the field of MDIs.
PULMONARY
Richard Molin
PROTECTING INHALATION DRUG DELIVERY DEVICES WITH PARYLENE CONFORMAL COATINGS
Dick Molin describes applications of Parylene coatings as protective barrier coatings in inhalable drug delivery devices, and the detailed characteristics of Parylene which make it particularly suited to these applications.
PULMONARY
Dr Carole Evans
Catalent Pharma Solutions
QUALITY BY DESIGN IN INHALATION PRODUCT DEVELOPMENT
Carole Evans and Lei Mao explore the application and principles of quality by design in the development, manufacture and commercialisation of inhaled pharmaceutical products.
PULMONARY
Dr Eunice Costa
Hovione
DESIGN OF COMPOSITE PARTICLES VIA SPRAY DRYING FOR DPI FORMULATIONS
Eunice Costa, Filipe Neves and Cláudia Moura describe how composite formulations - API embedded in an excipient matrix - overcome the challenges in inhalation powder development.
PULMONARY
Dr Joel Bell
EFFECTS OF STATIC ON PLASTICS USED IN DRUG DELIVERY DEVICES
Drug delivery in dry-powder and aerosol inhalers can be hindered by static attraction of the drug substance to plastics used in the drug flow path. JoelBell and Josh Blackmore report a series of projects to characterise this interaction.
EXPERT VIEW
Prof David Price
THE SIGNIFICANCE OF INHALER TECHNIQUE & HOW TO IMPROVE IT
Professor David Price describes a significant and long-standing unmet need for inhaler technique to be improved in patients with asthma and COPD, and sets forth strategies to achieve the sorely needed improvements.
PULMONARY
Bert Dekens
FORMULATION METHODS & SIZE REDUCTION FOR INHALERS
Bert Dekens highlights the importance of achieving the correct particle sizes, both for the API and the carrier in formulations for inhalation, and describes some of the available equipment most suited to specific tasks.
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