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RESPIRATORY

INHALIA<sup>®</sup>: A NEW pMDI METERING VALVE PLATFORM THAT PATIENTS CAN COUNT ON
PULMONARY
Inga Meyer
Nemera
INHALIA®: A NEW pMDI METERING VALVE PLATFORM THAT PATIENTS CAN COUNT ON
Inga Meyer introduces the company’s new pressurised metered-dose inhaler (pMDI) valve platform, Inhalia, and uses device testing study data to demonstrate some of the significant advances, advantages and benefits the platform brings.
HUMAN-CENTRED DESIGN & INHALATION DEVICE DEVELOPMENT
CONNECTIVITY
Bill Welch
Phillips Medisize
HUMAN-CENTRED DESIGN & INHALATION DEVICE DEVELOPMENT
Bill Welch explains how the term “smaller and smarter” applies in the development of inhalation devices, and describes how his company’s human-centred design approach.
PATIENT PREFERENCE IN RESPIRATORY DEVICE TRAINING & EDUCATIONAL TOOLS
PULMONARY
Paul Sullivan
Noble
PATIENT PREFERENCE IN RESPIRATORY DEVICE TRAINING & EDUCATIONAL TOOLS
Paul Sullivan and Craig Baker provide data from recent patient studies to emphasise the importance of training devices in improving adherence to, and compliance with, inhaled therapeutics.
WHY SUCCESS IN DRUG DELIVERY IS NOT JUST ABOUT THE DEVICE
EXPERT VIEW
Mark Tunkel
WHY SUCCESS IN DRUG DELIVERY IS NOT JUST ABOUT THE DEVICE
Mark Tunkel explains how companies developing and marketing inhalable pharmaceuticals can explore other strategies to improve patient outcomes over and above what the drug and device can achieve.
REVIEWING CURRENT THINKING ON THE <i>IN VIVO</i> BEHAVIOUR OF PARTICLES IN THE EXTRA-FINE REGION
PULMONARY
Dr David Lewis
REVIEWING CURRENT THINKING ON THE IN VIVO BEHAVIOUR OF PARTICLES IN THE EXTRA-FINE REGION
David Lewis reports the latest research on the changing view of the behaviour of particles in the extra-fine region and their potential for enhancing inhaled drug therapies.
IMPROVING DRUG STABILITY & DRUG DELIVERY BY MODIFICATION OF MDI CANISTER SURFACES
PULMONARY
Richard Turner
H&T Presspart
IMPROVING DRUG STABILITY & DRUG DELIVERY BY MODIFICATION OF MDI CANISTER SURFACES
Richard Turner explains how, in recent years, a number of surface coatings have been developed that can be applied to MDIs canisters and valve components, to protect the contents from deposition and degradation.
A NEW, ADVANCED HIGH-THROUGHPUT SYSTEM FOR AUTOMATED INHALER TESTING
PULMONARY
Adam Smith
Copley Scientific
A NEW, ADVANCED HIGH-THROUGHPUT SYSTEM FOR AUTOMATED INHALER TESTING
Adam Smith introduces DecaVertus, describing its single inhaler predecessor the Vertus, and how the DecaVertus design evolved using the Vertus technology.
INVESTIGATING THE DE-AGGLOMERATION PROFILES OF DPI FORMULATIONS
PULMONARY
Dr Paul Kippax
Malvern Panalytical
INVESTIGATING THE DE-AGGLOMERATION PROFILES OF DPI FORMULATIONS
Paul Kippax from Malvern Instruments, Srinivas Ravindra Babu Behara, David Morton, Ian Larson and Peter Stewart from Monash University describe the use of laser diffraction to analyse dry powder behaviour.
MDI PROPELLANTS – IS THE POPULARITY OF HFA 227EA SET TO GROW?
PULMONARY
Dr Timothy Noakes
MDI PROPELLANTS – IS THE POPULARITY OF HFA 227EA SET TO GROW?
Tim Noakes predicts a rise in demand for HFA 227ea – a less common MDI propellant than the better-known HFA 134a.
IMPROVING THE REALISM AND RELEVANCE OF MOUTH-THROAT MODELS FOR INHALED PRODUCT TESTING
PULMONARY
Mark Copley
Copley Scientific
IMPROVING THE REALISM AND RELEVANCE OF MOUTH-THROAT MODELS FOR INHALED PRODUCT TESTING
Mark Copley provides some background on mouth-throat models for OIP testing.
COMPANY SHOWCASE: NEMERA
RESPIRATORY
Isabelle Delcroix
Nemera
COMPANY SHOWCASE: NEMERA
In 2014, the healthcare business formerly known as Rexam Healthcare Devices became Nemera. This name change followed the May 2, 2014 acquisition by Montagu Private Equity.
THE ADVANTAGES OF DESIGNING HIGH-RESISTANCE SWIRL CHAMBERS
PULMONARY
David Harris
Team Consulting
THE ADVANTAGES OF DESIGNING HIGH-RESISTANCE SWIRL CHAMBERS
David Harris taps into a powerful combination of detailed anatomical and functional understanding of the human respiratory system, pulmonary drug delivery technology and formulation expertise.
PULMONARY DELIVERY OF ANTIMICROBIAL PEPTIDES
PULMONARY
Dr Anna Fureby
PULMONARY DELIVERY OF ANTIMICROBIAL PEPTIDES
Anna Fureby, Ulla Elofsson and Per Gerde discuss the serious problem of antibiotic resistance and the potential role of antimicrobial peptides in the treatment of resistant bacterial strains.
POLYMERS WITH IMPROVED TRIBOLOGY
RESPIRATORY
Dr Kirsten Markgraf
Celanese
POLYMERS WITH IMPROVED TRIBOLOGY
Kirsten Markgraf and Wendy Johnson review the performance of various polyoxymethylene acetal copolymer grades, and introduce two new grades optimised for sliding applications.
HUMAN-CENTRED DESIGN AT THE HEART OF A SUCCESSFUL PRODUCT DEVELOPMENT PROCESS
RESPIRATORY
Bill Welch
Phillips Medisize
HUMAN-CENTRED DESIGN AT THE HEART OF A SUCCESSFUL PRODUCT DEVELOPMENT PROCESS
Bill Welch and Jeremy Odegard provide an insight into how the company’s human centred design approach fits into its integrated product development process.
PROFITABLE ASSEMBLY AUTOMATION THROUGH USE OF STANDARDISED MACHINE PLATFORMS
RESPIRATORY
Reiner Zeidler
BBS Automation
PROFITABLE ASSEMBLY AUTOMATION THROUGH USE OF STANDARDISED MACHINE PLATFORMS
Reiner Zeidler describes the company’s modular TEAMED production system, and how it meets the inhaler device industry’s needs – from early development applications right through to commercial-scale manufacture.
EXPERTISE IN DEVELOPMENT, MANUFACTURING & COMMERCIALISATION
PULMONARY
EXPERTISE IN DEVELOPMENT, MANUFACTURING & COMMERCIALISATION
3M Drug Delivery Systems reports on how it has achieved significant successes thanks to its deep expertise in the field of MDIs.
PROTECTING INHALATION DRUG DELIVERY DEVICES WITH PARYLENE CONFORMAL COATINGS
PULMONARY
Richard Molin
PROTECTING INHALATION DRUG DELIVERY DEVICES WITH PARYLENE CONFORMAL COATINGS
Dick Molin describes applications of Parylene coatings as protective barrier coatings in inhalable drug delivery devices, and the detailed characteristics of Parylene which make it particularly suited to these applications.
SONIC NEBULISATION IN RHINOLOGY
NASAL
Dr Laurent Vecellio
SONIC NEBULISATION IN RHINOLOGY
Laurent Vecellio, Sandrine Le Guellec and Gilles Chantrel describe a sonic nasal nebuliser that operates with an acoustic frequency of 100Hz, and clinical studies demonstrating its efficacy in the delivery of treatments for CRS.
QUALITY BY DESIGN IN INHALATION PRODUCT DEVELOPMENT
PULMONARY
Dr Carole Evans
Catalent Pharma Solutions
QUALITY BY DESIGN IN INHALATION PRODUCT DEVELOPMENT
Carole Evans and Lei Mao explore the application and principles of quality by design in the development, manufacture and commercialisation of inhaled pharmaceutical products.
DESIGN OF COMPOSITE PARTICLES VIA SPRAY DRYING FOR DPI FORMULATIONS
PULMONARY
Dr Eunice Costa
Hovione
DESIGN OF COMPOSITE PARTICLES VIA SPRAY DRYING FOR DPI FORMULATIONS
Eunice Costa, Filipe Neves and Cláudia Moura describe how composite formulations - API embedded in an excipient matrix - overcome the challenges in inhalation powder development.
EFFECTS OF STATIC ON PLASTICS USED IN DRUG DELIVERY DEVICES
PULMONARY
Dr Joel Bell
EFFECTS OF STATIC ON PLASTICS USED IN DRUG DELIVERY DEVICES
Drug delivery in dry-powder and aerosol inhalers can be hindered by static attraction of the drug substance to plastics used in the drug flow path. JoelBell and Josh Blackmore report a series of projects to characterise this interaction.
THE SIGNIFICANCE OF INHALER TECHNIQUE & HOW TO IMPROVE IT
EXPERT VIEW
Prof David Price
THE SIGNIFICANCE OF INHALER TECHNIQUE & HOW TO IMPROVE IT
Professor David Price describes a significant and long-standing unmet need for inhaler technique to be improved in patients with asthma and COPD, and sets forth strategies to achieve the sorely needed improvements.
FORMULATION METHODS & SIZE REDUCTION FOR INHALERS
PULMONARY
Bert Dekens
FORMULATION METHODS & SIZE REDUCTION FOR INHALERS
Bert Dekens highlights the importance of achieving the correct particle sizes, both for the API and the carrier in formulations for inhalation, and describes some of the available equipment most suited to specific tasks.
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