advanced search

RESPIRATORY

ASSURE INHALER SAFETY & PERFORMANCE: POLYMERS, COLOUR & ADDITIVES
EXPERT VIEW
Stephen Duckworth
ASSURE INHALER SAFETY & PERFORMANCE: POLYMERS, COLOUR & ADDITIVES
Stephen J Duckworth describes some of the application of polymer colourants and additives in respiratory drug delivery devices, highlighting the strict regulatory environment.
PRODUCT SHOWCASE: BIOCORP’S INSPAIR<sup>™</sup>
PULMONARY
Jean Vuillecard
Biocorp
PRODUCT SHOWCASE: BIOCORP’S INSPAIR™
Inspair™ is a sensing technology able to measure inhalation metrics and therefore provide an accurate insight into actual doses consumed.
SELECTION OF EXCIPIENTS FOR DRY POWDER INHALERS
EXPERT VIEW
Harry Peters
SELECTION OF EXCIPIENTS FOR DRY POWDER INHALERS
Harry Peters and Gerald Hebbink explain how, because dry powder inhalers need a carrier to help with ensuring the drug is effectively delivered, interest has been focused on developing inhalation-grade lactose for this purpose.
LEVERAGE TECH TO OVERCOME PULMONARY DELIVERY BARRIERS
PULMONARY
Jean Vuillecard
Biocorp
LEVERAGE TECH TO OVERCOME PULMONARY DELIVERY BARRIERS
Jean Vuillecard and Eric Dessertenne define the limitations of traditional strategies to train, educate and track adherence with inhaled therapeutics and show how connectivity and other add-on digital tech can support these strategies healthcare providers require.
PATIENT PREFERENCE: DEVICE TRAINING & EDUCATION TOOLS
PULMONARY
Paul Sullivan
Noble
PATIENT PREFERENCE: DEVICE TRAINING & EDUCATION TOOLS
Paul Sullivan and Craig Baker point out that most patients with asthma do not use their inhaler properly, and review evidence from a trial of five different methods designed to improve inhaler use. They conclude that training devices could be effective tools to increase patient confidence and reduce anxiety.
AN ENVIRONMENTALLY FRIENDLY & EFFICIENT DOSAGE FORM
PULMONARY
Susana Ecenarro
Qualicaps
AN ENVIRONMENTALLY FRIENDLY & EFFICIENT DOSAGE FORM
Susana Ecenarro Probst presents evidence, set against the backdrop of environmental concerns over HFC propellants in MDIs, supporting the adoption of dry-powder inhalers as an attractive alternative.
LEARNING TO WALK BEFORE WE RUN
EXPERT VIEW
David Harris
LEARNING TO WALK BEFORE WE RUN
David Harris highlights basic problems with inhalers that persist today, and describes why - as the industry looks increasingly towards developing "smart" and connected inhalers - it is important to remember to solve these basic problems.
SCALING-UP FOR HIGH DOSE DELIVERY TO THE LUNGS
PULMONARY
Dr João Ventura Fernandes
SCALING-UP FOR HIGH DOSE DELIVERY TO THE LUNGS
João Ventura Fernandes, Gonçalo Rebelo de Andrade and Peter Villax describe the scaling up of the currently marketed TwinCaps® inhaler into the new TwinMax™ design for high-dose delivery of challenging drug-alone formulations in single to short-term treatments and emergency situations.
GENERIC NEBULISER BIOEQUIVALENCE: OPTIMISING ANALYTICAL STRATEGIES
PULMONARY
Déborah Le Pennec
Malvern Panalytical
GENERIC NEBULISER BIOEQUIVALENCE: OPTIMISING ANALYTICAL STRATEGIES
Déborah Le Pennec, Laurent Vecellio, Paul Kippax and Stephane Rouquette look at the optimal application of laser diffraction and automated imaging within the context of the US FDA guidance for the in vitro demonstration of bioequivalence in a generic nebuliser.
A TRUE PLATFORM OFFERING EFFICIENT NASAL DOSE DELIVERY
NASAL
Pascale Farjas
Nemera
A TRUE PLATFORM OFFERING EFFICIENT NASAL DOSE DELIVERY
Millions of people suffering from allergic rhinitis use nasal sprays manufactured by Nemera every day. Pascale Farjas, provides an overview of an innovative nasal delivery system, Advancia®, a true platform.
ADDING COLOUR & FUNCTIONALITY TO PLASTICS USED IN MEDICAL DEVICES
EXPERT VIEW
Stephen Duckworth
ADDING COLOUR & FUNCTIONALITY TO PLASTICS USED IN MEDICAL DEVICES
Stephen Duckworth explains how – with an emphasis on the importance of complying with stringent and changing pharmaceutical regulations – advanced additives in plastics used to make drug delivery devices can significantly enhance the product.
CONNECTED INHALERS MAKING A REAL IMPACT ON RESPIRATORY OUTCOMES
CONNECTIVITY
Garth Sutherland
Adherium
CONNECTED INHALERS MAKING A REAL IMPACT ON RESPIRATORY OUTCOMES
Garth Sutherland describes the problem of chronic non-adherence in asthma and COPD, how Adherium’s Smartinhaler™ solutions have proved themselves in the clinic, and why now is the time to move to real-world scale.
CONNECTED COMBINATION PRODUCTS: PAST, PRESENT & FUTURE
EXPERT VIEW
Napoleon Monroe
CONNECTED COMBINATION PRODUCTS: PAST, PRESENT & FUTURE
Napoleon Monroe provides an overview of connected health with a focus on drug delivery systems, beginning by showing that connected health has not suddenly emerged out of nowhere but, rather, it has been developing and evolving over many decades, even centuries.
THE MULTIPLE VALUES OF INTEGRATED SOLUTIONS
CONNECTIVITY
Eric Dessertenne
Biocorp
THE MULTIPLE VALUES OF INTEGRATED SOLUTIONS
Arnaud Guillet and Eric Dessertenne, both of Biocorp outline the potential value of the data that can be collected from integrated devices, not only for pharma companies but also for patients and payers.
ENHANCING THE PERFORMANCE OF DRY POWDER INHALERS: BREATH ACTUATED MECHANISMS
PULMONARY
Alan Tweedie
ENHANCING THE PERFORMANCE OF DRY POWDER INHALERS: BREATH ACTUATED MECHANISMS
David Lewis and Alan Tweedie explain how BAMs work and present experimental data demonstrating their ability to control dose delivery.
PRODUCT SHOWCASE: DF30 WITH COCe: ULTRA-CLEAN, ROBUST & VERSATILE
RESPIRATORY
Aptar Pharma
PRODUCT SHOWCASE: DF30 WITH COCe: ULTRA-CLEAN, ROBUST & VERSATILE
Aptar Pharma’s new DF30 metering valve version incorporates a cyclic-olefincopolymer (COC) neck gasket to enhance its performance further. It is the result of continuous improvement to today’s worldleading DF30 technology platform.
COMPANY SHOWCASE: NOBLE
PULMONARY
Noble
COMPANY SHOWCASE: NOBLE
Noble®, the leader in onboarding and device training, is a full-service, patient-centred product development and manufacturing company.
SYSTEMS ENGINEERING FOR COMPLEX PORTABLE DRUG DELIVERY DEVICE DEVELOPMENT
PULMONARY
Bill Welch
Phillips Medisize
SYSTEMS ENGINEERING FOR COMPLEX PORTABLE DRUG DELIVERY DEVICE DEVELOPMENT
Bill Welch explains how a systems-engineering approach provides an efficient method of developing smaller, smarter and more complex inhaler devices.
COMPANY SHOWCASE: NOVI
PULMONARY
Adam Smith
Copley Scientific
COMPANY SHOWCASE: NOVI
In December 2015 the inhaler automation specialists Novi Systems launched their latest product, a ten-way shake and fire system for pMDIs called DecaVertus. Novi continues to innovate, bringing efficiency, precision and repeatability to inhalation labs around the world.
IT’S JUST AN APP, ISN’T IT?
PULMONARY
Vaishali Kamat
Cambridge Consultants
IT’S JUST AN APP, ISN’T IT?
Vaishali Kamat and Jaquie Finn, outline some key questions that pharma companies should ask before embarking on the development of a connected health solution, and provide insights that could help companies make the most from their investment.
BIOEQUIVALENCE FOR NASAL SPRAYS: IMPORTANCE OF DEVICE PERFORMANCE
NASAL
Pascale Farjas
Nemera
BIOEQUIVALENCE FOR NASAL SPRAYS: IMPORTANCE OF DEVICE PERFORMANCE
Pascale Farjas describes the company’s Device Equivalence Program, which enables Nemera to preselect and propose an appropriate delivery system per identified drug to companies wishing to save time in their nasal spray development pipeline.
OPTIMAL SOLUTION FOR DIFFERENT INSPIRATIONAL RATES
PULMONARY
Dr Gabriela Dujovny
Qualicaps
OPTIMAL SOLUTION FOR DIFFERENT INSPIRATIONAL RATES
There is a wide range of devices available to deliver inhalation therapies, but there is increasing interest in the use of dry powder inhalers due to improved engineering and powder formulations. Gabriela Dujovny looks at the advantages and disadvantages of the DPIs currently available.
ADVANCES IN PULMONARY DELIVERY OF INHALED ANTI-INFECTIVES
PULMONARY
Dr David L Hava
ADVANCES IN PULMONARY DELIVERY OF INHALED ANTI-INFECTIVES
With the growing problems caused by antimicrobial resistance, there is increasing interest in the use of improved strategies for drug delivery. David L. Hava explores the benefits of nebulised inhaled antibiotics delivered via high throughput nebulisers for aqueous formulations or dry powder inhalations for cystic fibrosis patients.
FDA ISSUES FINAL GUIDANCE ON MEDICAL DEVICE HUMAN FACTORS STUDIES
RESPIRATORY
Dr Michael Gross
FDA ISSUES FINAL GUIDANCE ON MEDICAL DEVICE HUMAN FACTORS STUDIES
Michael Gross and Adam Shames discuss US FDA draft recommendations on human factors validation which are part of the design validation requirement of device design controls.
Top