advanced search

RESPIRATORY

BILL WELCH, PHILLIPS-MEDISIZE & JOHN PATTON, DANCE BIOPHARM
INTERVIEW
Dr John Patton
Aerami Therapeutics
BILL WELCH, PHILLIPS-MEDISIZE & JOHN PATTON, DANCE BIOPHARM
In this exclusive interview with ONdrugDelivery Magazine, Bill Welch and John Patton discuss inhaled insulin, connectivity and their two companies’ close partnership
REDUCING VARIABILITY IN TEST RESULTS FOR OINDPS WITH AUTOMATED ACTUATION
RESPIRATORY
Heli Chauhan
Proveris Scientific
REDUCING VARIABILITY IN TEST RESULTS FOR OINDPS WITH AUTOMATED ACTUATION
Heli Chauhan and Linda (Lingzhi) Liao discuss the importance of automated actuation for testing inhalation and spray devices to avoid variability introduced by manual method.
NASAL DRUG DELIVERY VIA THE ORAL ROUTE USING A PMDI
NASAL
Dr Laurent Vecellio
NASAL DRUG DELIVERY VIA THE ORAL ROUTE USING A PMDI
Laurent Vecellio, Déborah Le Pennec and Alain Regard, Technology Product Manage discuss a study Nemera has funded into the retronose concept, using a pMDI to deliver to the nasal cavity via the oral route during exhalation through the nose.
PIPELINE TRENDS AND CHALLENGES IN PULMONARY DELIVERY
EXPERT VIEW
Dr Gunilla Petersson
PIPELINE TRENDS AND CHALLENGES IN PULMONARY DELIVERY
Gunilla Petersson provides an overview of the inhalables sector from a pharma perspective, covering the three major device types – DPIs, pMDIs and nebulisers.
VARIABILITY IN CASCADE IMPACTION: SOURCES, IMPACT AND STRATEGIES FOR REDUCTION
PULMONARY
Mark Copley
Copley Scientific
VARIABILITY IN CASCADE IMPACTION: SOURCES, IMPACT AND STRATEGIES FOR REDUCTION
Mark Copley considers cascade impaction as a method for determining the aerodynamic particle size distribution of orally inhaled drug products, and how techniques to improve air flow control and semi-automation of the process can significantly reduce the variability involved.
MANUFACTURING DPIS: AN ENGINEERING PERSPECTIVE
PULMONARY
Pietro Pirera
IMA Group
MANUFACTURING DPIS: AN ENGINEERING PERSPECTIVE
Pietro Pirera and Stefano Crivellaro discuss the rising prominence of the DPI in inhalable drug delivery, how this has been facilitated by industrial filling technologies and how dosators in particular provide high-precision industrial-scale filling.
INTERTEK’S CENTRE OF EXCELLENCE FOR INHALED AND NASAL BIOLOGICS
RESPIRATORY
Chris Vernall
Intertek Pharmaceutical Services
INTERTEK’S CENTRE OF EXCELLENCE FOR INHALED AND NASAL BIOLOGICS
Chris Vernall discusses the significance and difficulties of biologics in the inhalables sector, and how Intertek’s Centre of Excellence for Inhaled and Nasal Biologics provides valuable services for those developing products in this area.
INTEGRATING CONNECTED HEALTH IN RESPIRATORY: THE MANUFACTURING CHALLENGE
EXPERT VIEW
David Belton
INTEGRATING CONNECTED HEALTH IN RESPIRATORY: THE MANUFACTURING CHALLENGE
David Belton highlights an often undiscussed aspect of the move towards connected drug delivery devices, the impact on manufacturing. Using inhalers as a reference point, he runs through several of the concerns and decisions that will need to be addressed for successful mass production of such devices.
GAS PLASMA PROCESSING: A LONG-TERM SOLUTION FOR RESPIRATORY DEVICES
INDUSTRIALISATION
Ameet Sule
H&T Presspart
GAS PLASMA PROCESSING: A LONG-TERM SOLUTION FOR RESPIRATORY DEVICES
Ameet Sule, Head of H&T Presspart’s Inhalation Product Technology Centre (IPCT), discusses the new challenges arising in metered dose inhaler design since the change from CFC to HFA propellants.
UPGRADING RESPIRATORY CARE WITH AI-POWERED SENSORS AND TRUE ADHERENCE DATA
CONNECTIVITY
Martijn Grinovero
Sanner Group
UPGRADING RESPIRATORY CARE WITH AI-POWERED SENSORS AND TRUE ADHERENCE DATA
Martijn Grinovero and Fabian Schütte describe the potential of artificial intelligence-powered sensors used in combination with standard inhalers to upgrade respiratory therapy.
MONITORING NEBULISER USAGE & LUNG FUNCTION IN CLINICAL TRIALS
CONNECTIVITY
Yvonne Koehler
PARI
MONITORING NEBULISER USAGE & LUNG FUNCTION IN CLINICAL TRIALS
Carola Fuchs and Yvonne Koehler, explain how PARI’s special eTrack® Controller can be used to monitor adherence during inhalation therapy which facilitates objective and remote monitoring.
CONNECTED DRUG DELIVERY SECTOR OVERVIEW
EXPERT VIEW
Tom Oakley
CONNECTED DRUG DELIVERY SECTOR OVERVIEW
Tom Oakley gives an overview of the state of connected devices in the drug delivery world, touching on various approaches, benefits and challenges in the sector today.
EXPANDING CONNECTIVITY: ADD-ONS FOR OPHTHALMIC AND NASAL DELIVERY
CONNECTIVITY
Nemera
EXPANDING CONNECTIVITY: ADD-ONS FOR OPHTHALMIC AND NASAL DELIVERY
Nemera introduces the e-Novelia® and e-Advancia® add-ons for ophthalmic and nasal devices.
LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING
EARLY INSIGHT
Dr Kian Min Lim
PA Consulting
LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING
Kian Min Lim and David Harris discuss how tailored algorithms can accurately detect inhalers’ acoustic signatures, effectively adding connectivity without having to add a chip to the inhaler.
THE FUTURE OF CONNECTED ASTHMA AND COPD CARE: A STEPWISE DEVELOPMENT
CONNECTIVITY
Dr Benjamin Jung
H&T Presspart
THE FUTURE OF CONNECTED ASTHMA AND COPD CARE: A STEPWISE DEVELOPMENT
Benjamin Jung outlines possible scenarios for the likely steps in the development and adoption of connected devices in the field of asthma and COPD care.
A POSITIVE SPIN ON DPI FORMULATION
EXPERT VIEW
Bert Dekens
A POSITIVE SPIN ON DPI FORMULATION
Bert Dekens outlines some of the considerations that go into developing and processing dry powder inhaler formulations, and discusses the merits of conical high-shear mixers.
POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY
EXPERT VIEW
Dr Karlheinz Seyfang
POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY
Karlheinz Seyfang discusses the need for filling verification in pre-metered DPI blister filling lines, going on to detail the role X-ray analysis could play in an automated verification process.
COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING
PULMONARY
Heli Chauhan
Proveris Scientific
COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING
Heli Chauhan outlines the major challenges encountered in testing pressurised metered dose inhalers, and how Proveris’ portfolio of instruments can be an invaluable addition to the testing workflow.
DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM
NASAL
Badre Hammond
Aptar Pharma
DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM
Badre Hammond, Gerallt Williams and Herve Pacaud discuss the growing trend of drug repurposing.
INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION
NASAL
Pascale Farjas
Nemera
INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION
Pascale Farjas, Alain Regard and Guillaume Grevin, discuss what is required of a modern nasal spray pump and how introducing the human factor showed a significant impact on the variability of delivered volume.
REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS
PULMONARY
Craig Baker
Noble
REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS
Craig Baker discusses the prevalence of improper use and how addressing this issue via training devices is of benefit to manufacturers, healthcare providers and patients.
THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES
EXPERT VIEW
Mary Hutchens
THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES
Mary Hutchens gives an overview of some of the changes wrought by last year’s introduction of the new EU Medical Device Regulation, with a specific view to its effect on inhalation devices and inhaled medical products.
CHOOSING THE RIGHT DOSATOR FOR DPI DOSING
EXPERT VIEW
Jamie Clayton
CHOOSING THE RIGHT DOSATOR FOR DPI DOSING
Jamie Clayton, Rajeev Dattani and Dave Seaward discuss the operation of dosators for reliable and accurate filling of DPI capsules and blisters.
MEETING FUTURE NEEDS FOR RESPIRATORY DRUG DELIVERY DEVELOPMENT
EXPERT VIEW
Mark Knowles
MEETING FUTURE NEEDS FOR RESPIRATORY DRUG DELIVERY DEVELOPMENT
Mark Knowles and Collette Johnson explore the different elements that need to be considered when developing a smart inhalation drug delivery device to ensure that maximum benefit is obtained.
Top