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RESPIRATORY

CONNECTED HEALTH – AN EFFECTIVE SOLUTION TO IMPROVE ADHERENCE
CONNECTIVITY
Sai Shankar
Aptar Pharma
CONNECTED HEALTH – AN EFFECTIVE SOLUTION TO IMPROVE ADHERENCE
Sai Shankar details the problem of non-adherence, in particular in asthma and COPD, and how its solution, along with myriad other benefits, can be found in digital healthcare and connected devices.
THE SCIENCE BEHIND CAPSULE-BASED DRY POWDER INHALATION TECHNOLOGY
PULMONARY
Fernando Díez
ACG
THE SCIENCE BEHIND CAPSULE-BASED DRY POWDER INHALATION TECHNOLOGY
Here, Fernando Díez, Justin Kalafat, and Jnanadeva Bhat explain the mechanics behind cDPIs, from the scientific perspective, before looking to the future of cDPIs in the market.
THE LATEST DIGITAL TOOLS REVEAL ACTUAL PATIENT BEHAVIOUR
EXPERT VIEW
Ryan Noble
THE LATEST DIGITAL TOOLS REVEAL ACTUAL PATIENT BEHAVIOUR
Ryan Noble and Tom Lawrie-Fussey discuss the potential of digital innovations to improve understanding of real patient behaviour and consequently increase adherence.
A SIMPLE AFFORDABLE DPI: MEETING THE NEEDS OF EMERGING MARKETS
PULMONARY
Dr Anselm Ebert
H&T Presspart
A SIMPLE AFFORDABLE DPI: MEETING THE NEEDS OF EMERGING MARKETS
Anselm Ebert, João Ventura Fernandes, Ameet Sule and Sunita Sule discuss the rising need for respiratory medication in the developing world. They go on to highlight the novel challenges presented by these new markets and explain how a new DPI, PowdAir Plus™, meets those challenges, offering a solution to the increase in chronic respiratory conditions across the globe.
ADDRESSING THE CHALLENGES IN NASAL DEVICE TESTING: EVALUATION OF PUMP PERFORMANCE
NASAL
Heli Chauhan
Proveris Scientific
ADDRESSING THE CHALLENGES IN NASAL DEVICE TESTING: EVALUATION OF PUMP PERFORMANCE
Heli Chauhan details the myriad challenges facing the OINDP market, with a particular emphasis on nasal spray devices, when it comes to testing products on a mass-production scale, such as a lack of adequate testing equipment and the need to capture accurate data consistently. She goes on to offer a solution in the form of Indizo®, Proveris’ automated nasal spray testing apparatus.
AN OVERVIEW OF DRY POWDER INHALATION FOR SYSTEMIC DRUG DELIVERY
PULMONARY
Brian E Jones
Qualicaps
AN OVERVIEW OF DRY POWDER INHALATION FOR SYSTEMIC DRUG DELIVERY
Brian Jones and Susana Ecenarro Probst discuss the growing interest in using inhaled APIs to treat systemic conditions. Furthermore, they review some of the methods used to engineer molecules to be suitable for DPI capsules and look to the possibility of administering biomolecules via the pulmonary route.
THE DEVELOPMENT PATH TO BIOEQUIVALENCE FOR A NASAL SPRAY
NASAL
Pascale Farjas
Nemera
THE DEVELOPMENT PATH TO BIOEQUIVALENCE FOR A NASAL SPRAY
Pascale Farjas, Alain Regard, and Céline Petitcolas discuss the steps taken when designing a nasal spray device for the growing bioequivalence market and the key competencies, including experience with regulations and regulatory agencies in numerous geographic regions, that Nemera can offer throughout the process.
DEVELOPING EFFECTIVE TRAINING DEVICES FOR THE PULMONARY HEALTHCARE MARKET
PULMONARY
Joe Reynolds
Noble
DEVELOPING EFFECTIVE TRAINING DEVICES FOR THE PULMONARY HEALTHCARE MARKET
Pulmonary drug delivery is an effective route of pharmaceutical administration but research has shown that a large majority of patients fail to use their devices properly, training devices can help address this problem. Joe Reynolds looks at the design challenges that need to be addressed as well as some of the latest features that can be incorporated to develop optimal training devices for patients.
A NOVEL POWDER FILLING TECHNOLOGY TO REDUCE DEVELOPMENT COSTS & TIMELINES
PULMONARY
Simon Strothers
3P Innovation
A NOVEL POWDER FILLING TECHNOLOGY TO REDUCE DEVELOPMENT COSTS & TIMELINES
Simon Strothers and Dave Seaward discuss the evolution of filling technology in the inhaled world, including a new technology and approach to filling which offers significant advantages over conventional filling systems.
KEY CONSIDERATIONS FOR NON-CLINICAL SAFETY ASSESSMENT OF INHALED BIOPHARMACEUTICALS
EXPERT VIEW
Dr Simon Moore
KEY CONSIDERATIONS FOR NON-CLINICAL SAFETY ASSESSMENT OF INHALED BIOPHARMACEUTICALS
Simon Moore, Kirsty Haprer and Sylwia Marshall highlight some of the key considerations for the development of inhaled biopharmaceuticals, including non-clinical safety assessment.
SMART DRUG DELIVERY: PRAGMATIC APPROACH REDUCES RISK, INCREASES INNOVATION & PATIENT ADHERENCE
CONNECTIVITY
Conor Mulcahy
Jabil Healthcare
SMART DRUG DELIVERY: PRAGMATIC APPROACH REDUCES RISK, INCREASES INNOVATION & PATIENT ADHERENCE
Getting patients to adhere to long-term therapy for asthma and chronic obstructive pulmonary disease remains a difficult issue to tackle. Conor Mulcahy discusses a smart inhaler which could help solve this problem.
EMBEDDED CONNECTED METERED DOSE INHALERS MEETING REQUIREMENTS FOR MASS ADOPTION
CONNECTIVITY
Dr Benjamin Jung
H&T Presspart
EMBEDDED CONNECTED METERED DOSE INHALERS MEETING REQUIREMENTS FOR MASS ADOPTION
Benjamin Jung and Dana Shears describe the role connected devices can play in the treatment of asthma and COPD, discuss the requirements for mass adoption, and introduce H&T Presspart's inhaler, the eMDI, which has connectivity fully embedded.
THE POTENTIAL OF CONNECTED DEVICES FOR TACKLING ASTHMA
EXPERT VIEW
Garth Sutherland
THE POTENTIAL OF CONNECTED DEVICES FOR TACKLING ASTHMA
Garth Sutherland and Jon-Paul Sherlock explain how a strategic partnership between pharmaceutical companies and digital health companies can achieve improved outcomes through joint initiatives.
WHAT IS QUALITY BY DESIGN AND WHY SHOULD YOU CARE?
PULMONARY
Proveris Scientific
WHAT IS QUALITY BY DESIGN AND WHY SHOULD YOU CARE?
Proveris Scientific explains quality by design (QbD), a scientific approach that formalises product design, automates manual testing, and streamlines troubleshooting.
THE IMPORTANCE OF SPRING AND STAMPING QUALITY IN INHALER SAFETY
PULMONARY
Bergdis Vogt
Baumann Medical
THE IMPORTANCE OF SPRING AND STAMPING QUALITY IN INHALER SAFETY
Frank Reiss and Bergdis Sigurdardottir explain how medical competence in spring and stamping manufacturing may prove critical for the developers of inhalers.
INNOVATIVE NASAL APPLICATION REQUIRES INNOVATIVE FILLING TECHNOLOGY
EXPERT VIEW
Dr Karlheinz Seyfang
INNOVATIVE NASAL APPLICATION REQUIRES INNOVATIVE FILLING TECHNOLOGY
Karlheinz Seyfang discusses the development of a system for the nasal delivery of a thixotropic gel formulation, from the design of the system through to the production line.
TRAINING DEVICE OPPORTUNITIES
PULMONARY
Joe Reynolds
Noble
TRAINING DEVICE OPPORTUNITIES
Joe Reynolds outlines the increasing range of options available for helping patients learn how to use their devices correctly and maximise the effectiveness of their treatments.
DIMITRI GRASSWILL, NEMERA
INTERVIEW
Dimitri Grasswill
Nemera
DIMITRI GRASSWILL, NEMERA
Dimitri Grasswill speaks with ONdrugDelivery Magazine, in the context of the changing market and technology around inhalation devices.
PRODUCT SHOWCASE: APTAR PHARMA’S MDI eDOSE COUNTER
PULMONARY
Aptar Pharma
PRODUCT SHOWCASE: APTAR PHARMA’S MDI eDOSE COUNTER
Aptar Pharma, will unveil its latest innovation, the eDose Counter for metered dose inhalers (MDIs), at the RDD Europe scientific conference in Antibes, France, on April 25-28, 2017.
DOSE COUNTERS & INDICATORS – MEETING A REAL PATIENT NEED
PULMONARY
Inga Meyer
H&T Presspart
DOSE COUNTERS & INDICATORS – MEETING A REAL PATIENT NEED
Inga Meyerand Kyle Wilson explain how their dose counter-enabled inhaler development work has led to the production of a system that accurately indicates the end of life of a device.
CONTROLLED-RELEASE SYSTEMS FOR PROTEINS & PEPTIDES
EXPERT VIEW
Dr S Mohan Mohanraj
CONTROLLED-RELEASE SYSTEMS FOR PROTEINS & PEPTIDES
S Mohan Mohanraj and Meier Kende discuss development of a viable intranasal microsphere-based delivery system and how it delivers a recombinant anthrax vaccine via two-dose immunisation.
BILL WELCH, PHILIPS-MEDISIZE
INTERVIEW
Bill Welch
Phillips Medisize
BILL WELCH, PHILIPS-MEDISIZE
Mr Welch gives ONdrugDelivery Magazine an exclusive preview of Phillips-Medisize’s forthcoming workshop, “Realizing the Benefits of Connected Health in Respiratory Drug Delivery”.
INTEGRATED DESIGN SPACE TO DEVELOP BETTER DPI FORMULATIONS
PULMONARY
Dr Filipa Maia
Hovione
INTEGRATED DESIGN SPACE TO DEVELOP BETTER DPI FORMULATIONS
Filipa Maia and Maria Palha report a study whose objective was to establish relationships between blend rheology, product performance and capsule filling process efficiency.
THE 21ST INTERNATIONAL SOCIETY FOR AEROSOLS IN MEDICINE CONGRESS
CONFERENCE SHOWCASE
Dr Philip Kuehl
THE 21ST INTERNATIONAL SOCIETY FOR AEROSOLS IN MEDICINE CONGRESS
The International Society for Aerosols in Medicine (ISAM) is a scientific society focused on all areas of aerosols including health effects of aerosols and pulmonary drug delivery.
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