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DELIVERING INTELLIGENT AUTOINJECTOR ASSEMBLY SOLUTIONS FOR COMPLEX CUSTOMER-SPECIFIC REQUIREMENTS

INDUSTRIALISATION

Lars Keinicke Hansen

Stevanato Group

DELIVERING INTELLIGENT AUTOINJECTOR ASSEMBLY SOLUTIONS FOR COMPLEX CUSTOMER-SPECIFIC REQUIREMENTS

Lars Keinicke Hansen discusses the potential of technology to enhance the efficiency and productivity of manufacturing processes for both pharmaceutical companies and contract development and manufacturing organisations, as well as the skills and expertise required to maximise the potential gains technology can offer.

FROM IDEA TO MASS PRODUCTION: RAPIDLY AND SAFELY INDUSTRIALISING INNOVATIONS

INDUSTRIALISATION

Michael Wiglenda

FROM IDEA TO MASS PRODUCTION: RAPIDLY AND SAFELY INDUSTRIALISING INNOVATIONS

Michael Wiglenda describes Gerresheimer’s approach to the industrialisation of drug delivery devices, using the production of the company’s Gx Inbeneo^® cartridge-based autoinjector as an example.

AUTOMATING HIGH-MIX, LOW-TO-MEDIUM-VOLUME AUTOINJECTOR ASSEMBLY

INDUSTRIALISATION

AUTOMATING HIGH-MIX, LOW-TO-MEDIUM-VOLUME AUTOINJECTOR ASSEMBLY

Colby Chen and Ian Chang discuss how the introduction of modularity can close the gap in traditional assembly systems to enable fully automated, high-quality autoinjector assembly in support of low- volume/high-mix manufacturing.

YPSOMED’S PLATFORM PRODUCT TRANSFORMATION AND APPROACH TO STRATEGIC PARTNER NETWORKING FOR SELF-INJECTION DEVICES

INDUSTRIALISATION

YPSOMED’S PLATFORM PRODUCT TRANSFORMATION AND APPROACH TO STRATEGIC PARTNER NETWORKING FOR SELF-INJECTION DEVICES

Ian Thompson describes how Ypsomed has transformed the market for platform-based self-injection devices and extended the concept of platform products beyond the core device by developing working practices with strategic networking partners, helping pharma companies and patients to source safe, reliable and easy-to-use drug-device combination products.

MACHINABILITY OF ETFE-FILM-COATED PREFILLED SYRINGE PLUNGER WITH VENT-TUBE INSERTION

INDUSTRIALISATION

Sebastien Cordier

MACHINABILITY OF ETFE-FILM-COATED PREFILLED SYRINGE PLUNGER WITH VENT-TUBE INSERTION

Sebastien Cordier, Benjamin Brocco, Audrey Chardonnet and Edgar Bauer discuss the results of tests on the performance of PremiumCoat^® syringe plungers on high-speed fill-finish operations with vented insertion.

MATERIAL SELECTION & EFFICIENT DEVELOPMENT PROCESSES FOR WEARABLE INJECTOR DRIVE SYSTEMS

Dave Beckstoffer

MATERIAL SELECTION & EFFICIENT DEVELOPMENT PROCESSES FOR WEARABLE INJECTOR DRIVE SYSTEMS

Dave Beckstoffer explains the importance of material selection in drive system development, the key attributes of materials towards a wearable and auto-delivery device, and discusses the need to achieve industrialisation based on material selection and relevant manufacturing processes.

IMPLEMENTING INDUSTRY 4.0: LESSONS LEARNED OVER TWO DECADES

INDUSTRIALISATION

IMPLEMENTING INDUSTRY 4.0: LESSONS LEARNED OVER TWO DECADES

Herman Rusch and Rob van den Brand present four lessons for implementing Industry 4.0 technology and practices in the drug delivery industry, which IGS GeboJagema has learned during its own journey to Industry 4.0 over the past 20 years.

USING EFFICIENT PROOF-OF-CONCEPT TESTS AND PILOT MOULDS FOR DEVICE DEVELOPMENT SUCCESS

USING EFFICIENT PROOF-OF-CONCEPT TESTS AND PILOT MOULDS FOR DEVICE DEVELOPMENT SUCCESS

Andreas Wild and Andreas Montag discuss the value of early proof-of-concept testing and sample production for drug delivery device development projects, with an emphasis on how partnership and consultation can smooth and enhance this process, including for design for automation and design for manufacturing considerations.

DIGITAL TWINS – A RAPIDLY GROWING TREND IN HEALTHCARE

NXP Semiconductors

DIGITAL TWINS – A RAPIDLY GROWING TREND IN HEALTHCARE

Sylvia Kaiser-Kershaw, Susanne Hazrati and Sebastian Muenscher examine how digital twinning, based on smart and secure wirelessly connected tags and labels, can transform healthcare processes.

SMART MEMS CAP FOR SHARPS WASTE: A SIMPLE AND ELEGANT SOLUTION TO CLINICAL TRIAL ADHERENCE MONITORING

SMART MEMS CAP FOR SHARPS WASTE: A SIMPLE AND ELEGANT SOLUTION TO CLINICAL TRIAL ADHERENCE MONITORING

Frank Leipold and Bernard Vrijens discuss Haselmeier & AARDEX’ s collaboration to develop the MEMS Smart Cap – a smart solution for data collection during clinical trials to enable an accurate assessment of participant nonadherence.

DIGITAL SELF-CARE – SOLVING PATIENT CHALLENGES WHILE DELIVERING BUSINESS INSIGHTS TO PHARMA

Dr Stefanie Seiler

DIGITAL SELF-CARE – SOLVING PATIENT CHALLENGES WHILE DELIVERING BUSINESS INSIGHTS TO PHARMA

Stefanie Seiler and Ventsislav Dobrev discuss self-care challenges for patients and highlight how Ypsomed Digital Health’s solutions can solve them while also delivering meaningful business insights for pharmaceutical companies.

OPTIMISING INHALATION ADHERENCE AND TECHNIQUE: THE POWER OF DIGITAL TECHNOLOGY

Dr Carola Fuchs

OPTIMISING INHALATION ADHERENCE AND TECHNIQUE: THE POWER OF DIGITAL TECHNOLOGY

Carola Fuchs and Rupa Ram discuss the development of PARI’s new eFlow Integrated Nebuliser and the PARI Breath Guide app, and how integrating these into the PARI Connect Platform will stimulate increased adherence to inhaled therapy and, therefore, improved therapeutic outcomes.

Interview with DEAN MINNOCK

Dr Dean Minnock

Interview with DEAN MINNOCK

Guy Furness and Dean Minnock discuss Innovation Zed’s unique origin story and digital connectivity add-on for injection pens. They dive into the value of digital ecosystems in the drug delivery industry and look towards the future as the company prepares to launch its third-generation add-on technology – DOSE.

BRINGING DIGITAL HEALTH AND DRUG DELIVERY TOGETHER TO SUPPORT SUBCUTANEOUS INJECTION IN ONCOLOGY

Aptar Digital Health

BRINGING DIGITAL HEALTH AND DRUG DELIVERY TOGETHER TO SUPPORT SUBCUTANEOUS INJECTION IN ONCOLOGY

Damien McKeon and Sueyoung Yoon discuss the trends driving interest in subcutaneous administration, the barriers to overcome and the characteristics of a patient-centric solution.

CLOSING THE LOOP: THE LATEST ON ARTIFICIAL PANCREAS SYSTEMS

Kamaal de Silva

CLOSING THE LOOP: THE LATEST ON ARTIFICIAL PANCREAS SYSTEMS

Kamaal de Silva looks at the future of closed-loop insulin delivery systems and how the management of Type 1 diabetes is developing in the digital era.

Interview with Eric Leven, Rip Road

Interview with Eric Leven, Rip Road

Guy Furness and Eric Leven discuss Rip Road’s work with SaMD applications, including the company's customisable platform for delivery device companion apps. Leven shares his thoughts on the potential of connectivity to enhance the patient experience of biologic therapies, based on years working in the digital space, as well as how far connected drug delivery has come and how far it has yet to go.

NAVIGATING THE TRANSITION: EXPLORING ALTERNATIVES TO TiO<sub>2</sub> IN PHARMACEUTICAL FORMULATIONS

Lucia Gurruchaga

NAVIGATING THE TRANSITION: EXPLORING ALTERNATIVES TO TiO₂ IN PHARMACEUTICAL FORMULATIONS

Lucía Gurruchaga discusses the push to develop an alternative opacifier and white colourant to titanium dioxide in the wake of the European Commission’s announcement that the additive may be banned in medicinal products, presenting data from recent testing on Qualicaps’ own novel alternative.

TACKLING IRON-DEFICIENCY ANAEMIA: A LEAP FORWARD WITH A REVOLUTIONARY BUCCAL PATCH

Dr Buddhadev Chaudhuri

TACKLING IRON-DEFICIENCY ANAEMIA: A LEAP FORWARD WITH A REVOLUTIONARY BUCCAL PATCH

Buddhadev P Chaudhuri and Frederik Ceyssens, discuss the challenges of iron-deficiency anaemia and introduce Keylika’s new buccal patch for iron delivery.

ADAPTING TO AN AGEING WORLD: FORMULATION STRATEGIES TO BOOST PATIENT COMPLIANCE

ADAPTING TO AN AGEING WORLD: FORMULATION STRATEGIES TO BOOST PATIENT COMPLIANCE

Jason Hunt and Yeli Zhang discuss the key factors undermining patient compliance in older adults and explore how the pharmaceutical industry can leverage excipients to enhance drug formulations and improve medication compliance among this critical demographic.

ARE ORAL FORMULATIONS OF OLIGONUCLEOTIDE THERAPEUTICS WITHIN REACH?

ARE ORAL FORMULATIONS OF OLIGONUCLEOTIDE THERAPEUTICS WITHIN REACH?

Nigel Theobald, discusses key issues and strategies for formulation scientists aiming to unlock the potential of oral delivery for small interfering ribonucleic acid drugs targeted against gastrointestinal diseases and cancers.

DIFFERENTIATING ORAL SUSPENSIONS WITH VERSATILE EXCIPIENTS

Mariona Venceslao Molins

DIFFERENTIATING ORAL SUSPENSIONS WITH VERSATILE EXCIPIENTS

Mariona Venceslao Molins and Liliana Miinea discuss how excipient-based approaches can facilitate patient-centric formulations and transform oral suspensions.

STRATEGIES TO MITIGATE GELATIN CROSS-LINKING IN ORAL SOLID DRUG DELIVERY

Dr Jnanadeva Bhat

STRATEGIES TO MITIGATE GELATIN CROSS-LINKING IN ORAL SOLID DRUG DELIVERY

Jnanadeva Bhat and Manali Dalvi discuss the factors contributing to gelatin cross-linking in oral solid dose delivery – and strategies to tackle the resulting challenges.

CANNABIDIOL DELIVERY THAT IS ON THE “TIP OF THE TONGUE”

Dr Zdravka Misic

CANNABIDIOL DELIVERY THAT IS ON THE “TIP OF THE TONGUE”

Zdravka Misic explores how formulation expertise can be applied to overcome the low bioavailability of cannabinoids and how innovation in orally disintegrating tablets is driving progress for cannabidiol-based therapeutics.

CHALLENGES IN TESTING THE ACCURACY OF INFUSION PUMP DOSES

CHALLENGES IN TESTING THE ACCURACY OF INFUSION PUMP DOSES

Lucas Foerster and Dieter Peissig explore the critical factors in choosing the right balance for infusion pump performance validation and discuss potential sources of error.

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