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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
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OUR AUTHORS
THE MAGAZINE
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RESPIRATORY
EXPERT VIEW
Dr Zaid Aqrawe
Merxin Ltd
SOFT MIST INHALERS VERSUS NEBULISERS: DELIVERY EQUIVALENCE & FUTURE THERAPIES
Zaid Aqrawe, Philippe Rogueda, Darragh Murnane and Bryan Eng, discuss the opportunity presented by soft mist inhalers as an alternative delivery device to nebulisers for inhaled therapies, contrasting the two device categories across multiple factors.
NASAL
Alain Regard
Nemera
ADDRESSING CNS THERAPIES THROUGH NOSE-TO-BRAIN PATHWAYS
Alain Regard, Raphaële Audibert and Audrey Chandra, discuss the advantages of nasal delivery and highlight the challenges of the nose-to-brain pathways.
NASAL
Shai Assia
Clexio Biosciences
HUMAN FACTORS IN THE ABSENCE OF A FAMILIAR MENTAL MODEL: CHALLENGES & OPPORTUNITIES IN DRUG SELF-ADMINISTRATION
Shai Assia explores the intricate challenge of designing drug-device combination products for self-administration by lay users without medical expertise, focusing on targeted nasal drug delivery devices.
INTERVIEW
Dr Julie Suman
Aptar Pharma
Interview: EXPLORING NASAL CASTS IN NASAL DRUG DEVELOPMENT
Julie Suman discusses nasal casts, their development, applications and significance for nasal drug product development.
INDUSTRIALISATION
Marcus Jarman-Smith
Victrex
ADVANCING PHARMACEUTICAL CONTACT APPLICATIONS WITH PEEK: MEETING INCREASING DEMANDS
Marcus Jarman-Smith and Yann Tréguier, discuss the myriad benefits that Victrex’s pharmaceutical-grade PEEK can offer to the drug delivery sector as a material of construction due to its versatile material properties.
PULMONARY
Dr Susana Saldanha
Hovione
HIGH-DOSE DELIVERY PLATFORM FOR CRYSTALLINE DPIs
Susana Saldanha, Lídia Santos and Rui Churro, discuss the benefits of crystalline formulations for inhalation devices.
INDUSTRIALISATION
Dr Alan Watts
Catalent Pharma Solutions
ARCUS
®
: A COMMERCIALISED TECHNOLOGY ENABLING HIGH-DOSE, HIGHLY RESPIRABLE POWDERS
Alan Watts and Michael Tauber, discuss the requirements and benefits of using spray-dried powders for inhalation, and how ARCUS, used for the successfully commercialised Inbrija® dry powder inhaler, is a prime example of this technology in action.
RESPIRATORY
Gemma Budd
Aptar Pharma
ADVANCING OINDP CLINICAL TRIALS WITH SPEED AND EFFICIENCY: STRATEGIES FOR SUCCESS
Gemma Budd and Julie Suman, consider the key issues that preclinical and clinical trials for orally inhaled and nasal drug products must address within the context of the information that regulators are looking for, providing insight, strategies and advice for both novel and generic products in this sector.
PULMONARY
Matthew Fenn
Copley Scientific
BETTER IN VIVO PREDICTION FROM OINDP TESTING: A GOAL WORTH PURSUING?
Matthew Fenn and Clair Brooks, consider the motivation for adopting more clinically representative test set-ups in orally inhaled and nasal drug product development and, more specifically, for the demonstration of bioequivalence, as well as the practicalities of doing so and the tools available to support such efforts.
INTERVIEW
Dr Sandy Munro
Phillips Medisize
Interview with Sandy Munro, Vectura
In this exclusive interview with ONdrugDelivery’s Guy Furness, Sandy Munro, PhD, of Vectura discusses his extensive career, focused on respiratory drug delivery. He shares his insights into current trends within the industry, including the growth of biologics, systemic delivery via inhalation, the potential of mesh nebulisers and connectivity in clinical trials.
PULMONARY
Gesa Braunlich
PARI
DEEP BREATHS, DEEP DIVES: THE NEW eFLOW INTEGRATED NEBULISER
Gesa Bräunlich and Michael Hahn discuss PARI’s new eFlow integrated nebuliser.
RESPIRATORY
Mike Needham
Kindeva
THE EVOLUTION OF PULMONARY & NASAL DRUG DELIVERY
Mike Needham takes a look at the history of, and progress in, inhalation technology and discusses what might lie ahead.
EXPERT VIEW
Dr Ethan Miller
BUBBLE-WRAPPED REMEDIES: HOW LIPID-ENCASED THERAPEUTICS COULD TRANSFORM INHALATION
Ethan Miller and Heather Jameson shed light on some of the intricacies that lipid-encapsulated therapeutics bring to the realm of inhalation therapies, and some considerations on how the type of inhalation device selected may help to mitigate issues around formulation stability and efficient delivery to target cells.
EXPERT VIEW
Dr Nia Stevens
HOW TO CHOOSE THE RIGHT INTRANASAL VACCINE DEVICE
Nia Stevens, discusses the potential benefits of developing vaccines for intranasal administration with a suitable drug delivery device, as well as the challenges associated with this delivery route.
EXPERT VIEW
Eric Kaneps
THE PATH TO NASAL DRUG PRODUCT COMMERCIALISATION
Eric Kaneps discusses the benefits of nasal drug delivery compared with other administration routes – and the challenges in R&D and clinical manufacturing.
EXPERT VIEW
Dr Carolina Dantas
EXPLORING THE POTENTIAL OF NEBULISED BIOLOGICS
Carolina Dantas and Ulf Krueger consider the challenges when it comes to the successful delivery of inhaled biological drugs.
PREFILLED SYRINGES
Alastair Willoughby
Team Consulting
DISCUSSION PRIMER: PHARMAPACK
Pharmapack’s organisers spoke with three industry experts, Alastair Willoughby, Jamie Greenwood and Chris Hurlstone, all from Team Consulting, to get their perspectives on the major trends expected to be top discussion topics at the event, and to play a significant role in the industry throughout 2024 and beyond.
CONNECTIVITY
Edgar Hernan Cuevas Brun
HCmed Innovations
CUSTOMISABLE NEBULISER PLATFORM TO MONITOR ADHERENCE
Edgar Hernan Cuevas Brun and Yuan-Ming Hsu discuss the value that customisable nebuliser platforms bring to patient adherence.
CONNECTIVITY
Joachim Koerner
Aptar Digital Health
IMPROVING MEDICATION ADHERENCE AND CLINICAL OUTCOMES THROUGH CONNECTED DRUG DELIVERY DEVICES
Joachim Koerner and Marcus Bates discuss the challenge that medication non-adherence presents to the healthcare sector, and the potential value of connected digital health solutions as a way of overcoming this challenge.
PULMONARY
Carolyn Berg
Catalent Pharma Solutions
SMART SCALING FOR SUCCESSFUL CAPSULE-BASED DRY POWDER INHALER FILLING USING DRUM TECHNOLOGIES
Carolyn Berg, William Chin and Patrick Goncalves discuss the considerations for filling capsules for dry powder inhalers across the various stages of clinical trials and commercialisation, and how to tackle the challenges of scaling up filling processes.
PULMONARY
Gladys Corrons-Bouis
Eveon
SPRAY DELIVERY: TARGETING PATIENT NEEDS AND EXPECTATIONS WITH PRECISION
Gladys Corrons-Bouis and Cyril Le Loc’h discuss the use of spray delivery for precise targeting of patient medication.
EXPERT VIEW
Ross Errington
FUTURE-PROOFING pMDI DESIGN TO FIT A CHANGING MARKET
Ross Errington explores how pharmaceutical companies can evolve their pMDI drug products to make them fit for the future considering the several recent regulatory changes that are transforming the landscape of inhalation drugs.
NASAL
Dr Marie-Christine Klein
URSATEC
CHALLENGES BESIDES DRUG TARGETING – REGULATORY HURDLES FOR MULTIDOSE NASAL SPRAYS
Marie-Christine Klein, Andreas Bilstein and Rouven Kraus, discuss recent regulatory changes affecting drug-device combination products, using the example of a multidose nasal spray.
EXPERT VIEW
Finn Heraghty
THE END OF THE ROAD FOR pMDIs?
Finn Heraghty and Heather Jameson explore the extent to which the healthcare needs of a population could be covered by the combined use of soft mist inhalers and dry powder inhalers, and discuss the factors that will impact the continued importance of pressurised metered dose inhalers going forward.
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