Gerresheimer

Gerresheimer offers innovative containment solutions, including drug pumps, syringes, pens, autoinjectors, inhalers, injection vials, ampoules, tablet containers, and infusion, dropper and syrup bottles, and digital solutions for therapy support.

Associated Companies

Sensile Medical

Corporate Headquarters
Gerresheimer AG
Klaus-Bungert-Straße 4
40468, Düsseldorf
Germany

Phone / Contact

T: +49 211 6181 00
F: +49 211 6181 295
E: [email protected]

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Gerresheimer offers a comprehensive portfolio of innovative containment solutions to the pharmaceutical, biotech and cosmetics industries, including for medicines, drug delivery systems and medical devices.

Its range of services and solutions includes digital solutions for therapy support, drug pumps, syringes, pens, autoinjectors and inhalers as well as injection vials, ampoules, tablet containers, infusion, dropper and syrup bottles.

Gerresheimer has 35 production sites in 16 countries in Europe, America and Asia, providing a global presence, and it produces locally for regional markets. With around 12,000 employees, the company generated sales of around €2 billion (£1.7 billion) in 2023.

Gerresheimer AG is listed on the MDAX of the Frankfurt Stock Exchange (ISIN: DE000A0LD6E6).

Articles by Gerresheimer

Dr Farid Seddighi

COMPREHENSIVE TESTING PROVES DESIGN CONCEPT OF NOVEL AUTOINJECTOR PLATFORM

Farid Seddighi, Sigrid Saaler-Reinhardt and Daniel Primavessy discuss the critical importance of testing at an early stage of medical device development, presenting an overview of the results that confirm the technical performance and usability of the novel Gx Inbeneo^® autoinjector.

THE IMPORTANCE OF USER-CENTRIC DESIGN WHEN DEVELOPING DEVICES FOR HOME USE

Simon Bürdel and Reza Abedian, discuss the importance and value of conducting human factors studies and user consultations above and beyond regulatory requirements when designing user-centric devices for subcutaneous self-injection in at-home settings.

INDUSTRIALISATION

Michael Wiglenda

FROM IDEA TO MASS PRODUCTION: RAPIDLY AND SAFELY INDUSTRIALISING INNOVATIONS

Michael Wiglenda describes Gerresheimer’s approach to the industrialisation of drug delivery devices, using the production of the company’s Gx Inbeneo^® cartridge-based autoinjector as an example.

BRINGING DIGITAL HEALTH AND DRUG DELIVERY TOGETHER TO SUPPORT SUBCUTANEOUS INJECTION IN ONCOLOGY

Damien McKeon and Sueyoung Yoon discuss the trends driving interest in subcutaneous administration, the barriers to overcome and the characteristics of a patient-centric solution.

Dr Daniel Primavessy

A NOVEL INSTRUMENT TO STREAMLINE COMBINATION PRODUCT DEVELOPMENT

Daniel Primavessy, Sigrid Saaler-Reinhardt, Katarzyna Maksymowicz and Marie Stockton introduce the Gx Inbeneo^® platform simulator. This tool supports pharmaceutical companies in bridging formulation and medical device development processes, reducing time to market for patient-centric combination products.

Dr Daniel Primavessy

GX INBENEO^® – DEVELOPING AN AUTOINJECTOR THAT RESPONDS TO THE CHALLENGES OF BIOLOGICS

Daniel Primavessy, Sigrid Saaler-Reinhardt, Katarzyna Maksymowicz and Marie Stockton, Marketing Manager discuss how the Gx Inbeneo^® autoinjector from Gerresheimer was purpose designed to provide an effective, easy-to-use solution for the subcutaneous self-administration of sensitive biopharmaceuticals.

SUSTAINABLE DESIGN OF A DRUG DELIVERY DEVICE FOR BIOPHARMACEUTICALS

Maike Wolf and Marie Stockton discuss how sustainability is a fundamental strategic priority for Gerresheimer. They also highlight how eco-design principles have been applied to the development of an on-body injector for subcutaneous delivery of biopharmaceuticals.

DIGITAL TWIN IN THE PHARMACEUTICAL SUPPLY CHAIN

Gerresheimer’s Ali Badiei explains the role of digital twin technology and its integration into the pharmaceutical supply chain, highlighting an innovative approach to ensuring drug identity and quality.

PREFILLED SYRINGES

SILICONE-OIL-FREE PREFILLED SYRINGE SYSTEMS – GUIDANCE FOR SELECTING THE APPROPRIATE PACKAGING MATERIALS AND FOR SILICONISATION

Bernd Zeiss addresses the influence of silicone oil on syringe systems and highlights the advantages and possibilities of novel silicone-oil-free prefillable syringes, both for glass and for plastic syringes.

PREFILLED SYRINGES

SILICONE-OIL-FREE, COATING-FREE, TUNGSTEN-FREE PREFILLABLE SYRINGES

Taras Bredel and Bernd Zeiss present the studies, development, performance and benefits of the Injecto lubrigone plunger stopper combined with the Gerresheimer RTF^® glass syringe – a silicone-oil-free, coating-free, tungsten-free, low-particle prefilled syringe solution for sensitive drug products.

INDUSTRIALISATION

INDUSTRIALISATION OF PHARMACEUTICAL AND MEDICAL DEVICES IN THE SCIENTIFIC MOULDING APPROACH

Thomas Rudolph, Markus Reil, Stefan Schumann and Tobias Weigert discuss Gerresheimer’s strategy for managing potential risks across the entire product lifecycle.

PREFILLED SYRINGES

Dr Wenzel Novak

GX INNOSAFE – GREATER PROTECTION AGAINST NEEDLESTICK INJURIES

Wenzel Novak and Stefan Verheyden introduce Gx InnoSafe, a novel integrated passive needle safety system for preventing needlestick injuries and accidental reuse of syringes that minimises additional burden on healthcare workers during injection and can be integrated into existing pharmaceutical filling operations without the need for adaptation or conversion of processing lines.

DEVELOPMENT & PRODUCTION OF RESPIMAT^® REUSABLE INHALER HOUSING MODULE

Josef Schmid, Markus Müller and Nina Zielonka discuss Gerresheimer’s recent work on developing the housing module for Boehringer Ingelheim’s new version of the Respimat inhaler.

PREFILLED SYRINGES

Mr Maximilian Vogl

GERRESHEIMER INCLUDES STEVANATO GROUP INTEGRATED TWIST-OFF CLOSURE SYSTEM FOR GX^® RTF SYRINGES

Maximilian Vogl reveals the latest user-friendly addition to its Gx RTF Luer lock syringes using Stevanto Group’s integrated twist-off closure technology.

Gerresheimer part of critical infrastructure, products include vital drug delivery devices

In its COVID-19 announcement, Gerresheimer has stated that it is part of the critical infrastructure of the countries in which it operates, producing vital packaging for medicines, drug delivery devices and packaging for food, beverages and hygiene and personal care products.

PREFILLED SYRINGES

Mr Maximilian Vogl

Gerresheimer Expands Gx RTF^® ClearJect^® Product Line

Maximilian Vogl describes how Gerresheimer is expanding its range of prefillable polymer syringes to include a new product: the Gx RTF^® ClearJect^® polymer syringe, 2.25 mL.

INDUSTRIALISATION

Michael Wiglenda

A FIVE-STEP APPROACH TO INNOVATION IN DRUG DELIVERY SYSTEMS

Michael Wiglenda explains Gerresheimer’s industrialisation offering and the five-step Gate-Model that guides its innovation process.

INDUSTRIALISATION

Michael Wiglenda

A COMPREHENSIVE APPROACH TO PHARMA INDUSTRIALISATION PARTNERING

As a company offering contract services at every stage of drug delivery system development, Gerresheimer has a wealth of expertise and history in industrial-scale production. Michael Wiglenda explains Gerresheimer’s industrialisation offering in detail.

PREFILLED SYRINGES

Claudia Petersen

PREFILLABLE SYRINGE DEVELOPMENTS TO MEET BIOTECH DRUG NEEDS

Claudia Petersen looks at the technological advances being made to ensure prefillable syringes are compatible with protein-based, biotech-derived drugs.

PREFILLED SYRINGES

LUBRICIOUS COATINGS TO REDUCE SILICONE OIL & PARTICLE LEVELS

The market for prefilled syringes continues to grow as does the number of approved biologics delivered in this manner. Bernd Zeiss and Susan Dounce outline the results of a study using the combination of a Gx Baked-on RTF® syringe and the OmniflexCP® plunger.

PREFILLED SYRINGES

Dr Andrea Behrenswerth

CRACK PREVENTION & PROCESS CONTROLS IN PREFILLABLE SYRINGE MANUFACTURING

Andrea Behrenswerth and Marc-Oliver Luther both of Gerresheimer Bünde, and Bernhard Hinsch of Hinsch Consulting (Hamburg, Germany), explain the most frequently encountered types of defects, their causes and specific approaches to process optimisation.

PREFILLED SYRINGES

Dr Felix Weiland

INSPECTION TECHNOLOGIES FOR GLASS SYRINGES

Today, high standards for glass syringes are achieved with a combination of visual and camera-based inspection technologies. Bernhard Hinsch argues that both technologies deliver reliable results, if all relevant input variables are known and a model of their interaction has been created, but camera-based inspections are the preferred solution.

SAFE & RELIABLE PRIMARY DRUG CONTAINER MANUFACTURING

Gerresheimer, leader in the manufacture of parenteral drug delivery systems and primary packaging, including standard and customised glass vials, ampoules and cartridges, provides a brief overview of the manufacturing process.

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