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PULMONARY

ROUNDTABLE: CAPSULE-BASED DRY POWDER INHALERS
ROUNDTABLE
Frédérique Bordes-Picard
Lonza
ROUNDTABLE: CAPSULE-BASED DRY POWDER INHALERS
Frédérique Bordes-Picard of Lonza, Marco Franza of Berry, Mirjam Kobler of Meggle, and Marco Laackmann of Harro Höfliger, discuss the accelerating development potential of capsule-based dry powder inhalers (DPIs) and the potential of these effective and efficient drug delivery devices in the modern drug delivery market.
TRANSFORMING DRUG DELIVERY WITH SYNERGISTIC WORKING
PULMONARY
Bas van Driel
DFE Pharma
TRANSFORMING DRUG DELIVERY WITH SYNERGISTIC WORKING
Bas van Driel discusses how expert collaborations can help develop a knowledge base to transform drug delivery and manufacturing. He shares how recent collaborative research projects involving lactose-based dry powder inhalation formulations, with and without magnesium stearate and lactose as an excipient in 3D tablet printing, have done just that.
SUCCESSFULLY BALANCING THE NEEDS OF THE PLANET WITH THE NEEDS OF THE PATIENT
SUSTAINABILITY
Julien Storz
Aptar Pharma
SUCCESSFULLY BALANCING THE NEEDS OF THE PLANET WITH THE NEEDS OF THE PATIENT
Christophe Marie, Taylor Price and Julien Storz chart the commitments and progress made to date by Aptar in achieving its sustainability targets. The authors also provide examples of integrated, circular economy initiatives undertaken by Aptar Pharma at a product solution level and comment on concrete commitments that can be made to further progress towards sustainability.
SIX INHALER SUSTAINABILITY MYTHS – AND WHY THEY MUST BE BUSTED
SUSTAINABILITY
Louise Righton
Kindeva
SIX INHALER SUSTAINABILITY MYTHS – AND WHY THEY MUST BE BUSTED
Louise Righton busts six sustainability myths about inhalers.
PLASMA TECHNOLOGY – THE FUTURE OF RESPIRATORY DEVICES
SUSTAINABILITY
Jacqueline Green
H&T Presspart
PLASMA TECHNOLOGY – THE FUTURE OF RESPIRATORY DEVICES
Jacqueline Green discusses how H&T Presspart’s plasma treatment process can provide a future-proof and sustainable solution for some of the issues associated with suspension formulations in the respiratory device industry.
CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS
CONNECTIVITY
Marcus Jarman-Smith
Victrex
CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS
Marcus Jarman-Smith, Adam Salmen, John Devine, Ernst Hupkes and Dennis Freie discuss the value of PEEK, a high-performance polymer, in drug delivery device design, using two concept devices – an on-body patch pump and vaporiser inhaler.
MEANING-CENTRED PRODUCT DEVELOPMENT: THE KEY TO SUCCESSFUL CONNECTED DISEASE MANAGEMENT
CONNECTIVITY
Christina Philpott
MEANING-CENTRED PRODUCT DEVELOPMENT: THE KEY TO SUCCESSFUL CONNECTED DISEASE MANAGEMENT
Christina Philpott, Miles Hawley and Natasha French, discuss the future of connected disease management and the potential benefits for asthma treatment.
PUTTING THEIR HEALTH IN THEIR HANDS: ENHANCING RESPIRATORY PATIENT OUTCOMES THROUGH DIGITAL THERAPEUTICS
CONNECTIVITY
Adam Shain
Aptar Pharma
PUTTING THEIR HEALTH IN THEIR HANDS: ENHANCING RESPIRATORY PATIENT OUTCOMES THROUGH DIGITAL THERAPEUTICS
Adam Shain discusses the role digital therapeutics play in respiratory patient outcomes and looks at the potential for expansion into other therapy areas.
SPECIALTY LCP COMPOUNDS FOR ELECTRONICS INTEGRATION IN CONNECTED MEDICAL DEVICES
CONNECTIVITY
Dr Young Kim
Celanese
SPECIALTY LCP COMPOUNDS FOR ELECTRONICS INTEGRATION IN CONNECTED MEDICAL DEVICES
Young Kim, Don DeMello and Philip Wilson, discuss the benefits of recent advances in liquid crystal polymer for connected medical devices.
PRACTICAL INSIGHTS INTO LACTOSE-BASED DPI FORMULATIONS, WITH & WITHOUT MAGNESIUM STEARATE
RESPIRATORY
Harry Peters
DFE Pharma
PRACTICAL INSIGHTS INTO LACTOSE-BASED DPI FORMULATIONS, WITH & WITHOUT MAGNESIUM STEARATE
Partners DFE Pharma, Hosokawa Micron and Harro Höfliger describe their unique multidisciplinary study into lactose-based DPI formulations including magnesium stearate, whose findings will give generic players a head-start in the development process so that they can tap into this rapidly growing market. The three companies announce that they will be presenting the key insights from their research to interested parties during a joint webinar on the June 30th, 2020.
SPRAY CHARACTERISATION TESTING FOR ORALLY INHALED AND NASAL DRUG PRODUCTS
RESPIRATORY
Francois Billard
Recipharm
SPRAY CHARACTERISATION TESTING FOR ORALLY INHALED AND NASAL DRUG PRODUCTS
Francois Billard and Lei Mao look at measurement systems for spray pattern and plume geometry dispensed by orally inhaled and nasal drug products.
CHARACTERISATION OF LACTOSE POWDERS FOR DPI APPLICATIONS
PULMONARY
Dr Aurelien Neveu
Granutools
CHARACTERISATION OF LACTOSE POWDERS FOR DPI APPLICATIONS
Aurélien Neveu, Michael Crowley and Tony McGorisk discuss the characterisation of lactose powders for use as excipients in DPI formulations. The authors go on to discuss an analysis of six Kerry lactose powders using GranuTools technology.
BIOCOMPATIBILITY OF MEDICINAL PRODUCT MEDICAL DEVICE COMBINATIONS FOR AIRWAY DELIVERY
EXPERT VIEW
Mark Turner
BIOCOMPATIBILITY OF MEDICINAL PRODUCT MEDICAL DEVICE COMBINATIONS FOR AIRWAY DELIVERY
Mark Turner discusses biocompatibility testing for inhaled medical products, with particular reference to ISO 18562, and what Medical Engineering Technologies has learned from three years of breathing component biocompatibility testing.
RS01X – BERRY GLOBAL HEALTHCARE’S SINGLE-DOSE DPI GOES DIGITAL WITH AMIKO’S RESPIRO
CONNECTIVITY
Mauro Citterio
RS01X – BERRY GLOBAL HEALTHCARE’S SINGLE-DOSE DPI GOES DIGITAL WITH AMIKO’S RESPIRO
Mauro Citterio, Director, Marco Franza and Martijn Grinovero discuss Berry and Amiko’s partnership to develop the RS01X connected single-dose dry powder inhaler, based on Berry’s commercialised RS01 inhaler and Amiko’s Respiro digital health platform.
IMPROVING INHALATION THERAPY ADHERENCE WITH CONNECTED DEVICES
CONNECTIVITY
Edgar Hernan Cuevas Brun
HCmed Innovations
IMPROVING INHALATION THERAPY ADHERENCE WITH CONNECTED DEVICES
 Edgar Hernan Cuevas Brun discusses the role of connectivity in improving adherence to medication and introduces the company’s mesh nebuliser smart cap, Pulmogine+.
AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING
PULMONARY
Frédérique Bordes-Picard
Lonza
AN ADVANCED CUSTOMISABLE COMPREHENSIVE DPI CAPSULE PORTFOLIO OFFERING
Frédérique Bordes-Picard and Julien Lamps discuss the factors driving development in the area of capsule-based dry powder inhalers, and how the company’s Capsugel® Zephyr™ portfolio offering is perfectly positioned to meet and exceed industry’s growing and evolving requirements.
DEVELOPMENT & PRODUCTION OF RESPIMAT<sup>®</sup> REUSABLE INHALER HOUSING MODULE
RESPIRATORY
Josef Schmid
Gerresheimer
DEVELOPMENT & PRODUCTION OF RESPIMAT® REUSABLE INHALER HOUSING MODULE
Josef Schmid, Markus Müller and Nina Zielonka discuss Gerresheimer’s recent work on developing the housing module for Boehringer Ingelheim’s new version of the Respimat inhaler.
AN INTRODUCTION TO SMART BREATH-ACTUATED NEBULISERS
PULMONARY
Edgar Hernan Cuevas Brun
HCmed Innovations
AN INTRODUCTION TO SMART BREATH-ACTUATED NEBULISERS
Edgar Hernan Cuevas Brun considers the benefits of smart breath-actuated nebulisers and looks at the latest technology contributing to the evolution of nebulisers.
ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS
INDUSTRIALISATION
Bert Dekens
ONE-STOP SHOP FOR TOTAL MIXING SOLUTIONS FOR PHARMACEUTICAL MANUFACTURERS
Bert Dekens discusses Hosokawa Micron's offering for pharmaceutical powder mixing, including the Cyclomix high-shear mixer and the Nauta low-shear mixer, and how the company’s technology solutions take a broader approach to the full mixing process than simply providing a mixing machine.
SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES
PULMONARY
João Pereira
Hovione
SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES
João Pereira, Raquel Borda D’Água, Mark Copley and Anna Sipitanou, discuss the semi-automation of cascade impactor testing and the benefits it can bring in terms of quality of orally inhaled product test data, and reductions in cost and effort associated with routine, critical measurements.
COLD FILLING VERSUS PRESSURE FILLING: THE CASE FOR VERSATILE, FULLY INTEGRATED CDMOs
RESPIRATORY
Steve Haswell
Kindeva
COLD FILLING VERSUS PRESSURE FILLING: THE CASE FOR VERSATILE, FULLY INTEGRATED CDMOs
Steve Haswell compares the two main processes for manufacturing pressurised metered dose inhalers – and examines the value for pharmaceutical companies of working with contract development and manufacturing organisations that have expertise in both processes.
PULMO<emp>CRAFT</emp>™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY
PULMONARY
Dr Richard Johnson
Upperton Pharma Solutions
PULMOCRAFT™: ENGINEERING SPRAY-DRIED POWDERS FOR PULMONARY DELIVERY
Richard Johnson discusses the techniques of jet milling and spray drying for the production of formulations for dry powder inhalers, and introduces Upperton Pharma’s PulmoCraft™ technology, which combines the advantages of both.
EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES
PULMONARY
Dr Sion Coulman
EVALUATING THE MECHANICAL PROPERTIES OF “EXTRA DRY” HARD-SHELL CAPSULES
Sion Coulman, Siamac Parker, Prof James Birchall, Susana Ecenarro and Mahmoud Farag discuss new developments in low moisture content capsule technology for hygroscopic and very moisture-labile APIs.
HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY
RESPIRATORY
Howard Burnett
Aptar Pharma
HOW EMOTIONAL INTELLIGENCE IS DRIVING IMPROVEMENTS & MEETING CHALLENGES IN PULMONARY DELIVERY
Howard Burnett explores how emotional intelligence can foster partnerships that have the potential to drive advances in understanding and improving patient outcomes, and presents the case for a single-source, turnkey approach to pulmonary solution development.
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